Lehne's Pharmacology for Nursing Care -
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
UNIT I: INTRODUCTION
Chapter 1 – Orientation to Pharmacology
Lehne’s Pharmacology for Nursing Care, 12th Edition
EXACTLY 20 Fast-Revision NCLEX-Style MCQs
1. Which statement best defines pharmacology?
A. Study of drug costs and distribution
B. Study of drug effects on living systems
,C. Study of herbal therapies only
D. Study of disease pathology
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their
interactions with living systems, including therapeutic and
adverse effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology.
2. Pharmacotherapeutics is primarily concerned with:
A. Drug absorption pathways
B. Clinical use of drugs to prevent and treat disease
C. Drug metabolism in the liver
D. Molecular drug structure
Correct Answer: B
Rationale: Pharmacotherapeutics focuses on using drugs to
diagnose, prevent, and treat disease.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
3. Which branch of pharmacology studies how the body
affects a drug?
A. Pharmacodynamics
B. Pharmacokinetics
,C. Toxicology
D. Pharmacognosy
Correct Answer: B
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion (ADME).
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
4. A nurse explains that drug-receptor interaction produces a
response. This refers to:
A. Pharmacokinetics
B. Drug tolerance
C. Pharmacodynamics
D. Bioavailability
Correct Answer: C
Rationale: Pharmacodynamics examines how drugs produce
effects, including receptor interactions.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
5. A drug that binds to a receptor and activates it is classified
as a:
A. Antagonist
B. Agonist
, C. Partial inhibitor
D. Toxicant
Correct Answer: B
Rationale: An agonist binds to receptors and mimics
endogenous substances to produce a response.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
6. A competitive antagonist works by:
A. Destroying receptors
B. Blocking receptor activation
C. Increasing receptor sensitivity
D. Enhancing endogenous ligand release
Correct Answer: B
Rationale: Competitive antagonists bind to receptors without
activating them, preventing agonist effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
7. The nurse recognizes which term describes the strength of
receptor binding?
A. Efficacy
B. Potency
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
UNIT I: INTRODUCTION
Chapter 1 – Orientation to Pharmacology
Lehne’s Pharmacology for Nursing Care, 12th Edition
EXACTLY 20 Fast-Revision NCLEX-Style MCQs
1. Which statement best defines pharmacology?
A. Study of drug costs and distribution
B. Study of drug effects on living systems
,C. Study of herbal therapies only
D. Study of disease pathology
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their
interactions with living systems, including therapeutic and
adverse effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch. 1
– Orientation to Pharmacology.
2. Pharmacotherapeutics is primarily concerned with:
A. Drug absorption pathways
B. Clinical use of drugs to prevent and treat disease
C. Drug metabolism in the liver
D. Molecular drug structure
Correct Answer: B
Rationale: Pharmacotherapeutics focuses on using drugs to
diagnose, prevent, and treat disease.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
3. Which branch of pharmacology studies how the body
affects a drug?
A. Pharmacodynamics
B. Pharmacokinetics
,C. Toxicology
D. Pharmacognosy
Correct Answer: B
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion (ADME).
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
4. A nurse explains that drug-receptor interaction produces a
response. This refers to:
A. Pharmacokinetics
B. Drug tolerance
C. Pharmacodynamics
D. Bioavailability
Correct Answer: C
Rationale: Pharmacodynamics examines how drugs produce
effects, including receptor interactions.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
5. A drug that binds to a receptor and activates it is classified
as a:
A. Antagonist
B. Agonist
, C. Partial inhibitor
D. Toxicant
Correct Answer: B
Rationale: An agonist binds to receptors and mimics
endogenous substances to produce a response.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
6. A competitive antagonist works by:
A. Destroying receptors
B. Blocking receptor activation
C. Increasing receptor sensitivity
D. Enhancing endogenous ligand release
Correct Answer: B
Rationale: Competitive antagonists bind to receptors without
activating them, preventing agonist effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
7. The nurse recognizes which term describes the strength of
receptor binding?
A. Efficacy
B. Potency
