Part I: Basic Immunologic Mechanisms
x x x x
1. Highlights of Innate and Adaptive Immune Systems
x x x x x x
2. Soluble Mediators of the Immune System
x x x x x
3. Antigens and Antibodies x x
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
x x x x x x x x x
Part II: The Theory of Immunologic and Serologic Procedures
x x x x x x x x
5. Basic Safety in the Immunology-Serology Laboratory
x x x x x
6. Quality Assurance and Quality Control Practices
x x x x x
7. Basic Serologic Laboratory: Techniques and Clinical Applications
x x x x x x
8. Precipitation and Particle Agglutination Methods x x x x
9. Electrophoresis Techniques x
10. Labeling Techniques in Immunoassay x x x
11. Flow Cytometry x
12. Molecular Laboratory Techniques x x
Part III: Immunologic Manifestations of Infectious Diseases
x x x x x x
13. Infectious Diseases: Overview & TORCH Diseases x x x x x
14. Streptococcal Infections x
15. Syphilis
16. Vector-Borne Diseases x
17. Infectious Mononucleosis x
18. Viral Hepatitis x
Part IV: Immune Disorders
x x x
19. Primary and Acquired (Secondary) Immune Deficiencies
x x x x x
20. Hypersensitivity Reactions x
21. Immunoproliferative Disorders x
22. Tolerance, Autoimmunity and Autoimmune Disorders x x x x
23. Systemic Lupus Erythematosus x x
,24. Rheumatoid Arthritis x
Part V: Transplantation & Tumor Immunology
x x x x x
25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
x x x x x x x
26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
x x x x x x x x
Part VI: Vaccines
x x
27. Primer on Vaccines x x
Chapter 01: Highlights ofthe Innate andAdaptive Immune Systems
x x x x x x x x x
MULTIPLE CHOICE x
1. The―father‖ ofimmunologyisgenerallyconsidered to be
x x x x x x x x
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B x
, Louis Pasteur is generally considered to be the ―father of immunology.‖
x x x x x x x x x x
DIF: Cognitive Level: I x x
2. An early form of immunization was practiced by the
x x x x x x x x
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. x
ANS: C x
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders
x x x x x x x x x x x x x x
derived from the crusts of smallpox lesions.
x x x x x x x
DIF: Cognitive Level: I x x
3. A specific function of the immune system is to
x x x x x x x x
a. recognize self from nonself. x x x
b. defend the body against nonself. x x x x
c. amplify specific functions. x x
d. Both A and B. x x x
ANS: D x
The function ofthe immune system is to recognize self from nonself and defend the body against
x x x x x x x x x x x x x x x x
nonself. Such a system is necessary for survival. The immune system also has nonspecific
x x x x x x x x x x x x x x
effector mechanisms that usually amplify the specific functions. Nonspecific components of the
x x x x x x x x x x x x
immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble
x x x x x x x x x
factors (e.g., complement).
x x x
DIF: Cognitive Level: I x x
4. An undesirable consequence of immunity is
x x x x x
a. natural resistance. x
b. acquired resistance to infectious diseases. x x x x