Usmle Step 1 First Aid
often precedes squamous cell carcinoma ------- ✔ CORRECT ANSWER ✓✓actinic keratosis
primary adrenocortical deficiency ------- ✔ CORRECT ANSWER ✓✓Addison's disease
polyostotic fibrous dysplasia, precocious puberty, cafe-au-lait spots, short stature, young girls -
diagnosis? ------- ✔ CORRECT ANSWER ✓✓Albright's syndrome
hereditary nephritis with nerve deafness ------- ✔ CORRECT ANSWER ✓✓Alport's syndrome
anti-basement membrane antibodies - diagnosis? ------- ✔ CORRECT ANSWER
✓✓Goodpasture's syndrome
anticentromere antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓scleroderma (CREST)
anti-double-stranded DNA antibodies (ANA antibodies) - diagnosis?
- what hypersensitivity type? ------- ✔ CORRECT ANSWER ✓✓SLE - type III hypersensitivity
anti-epithelial cell antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓pemphigus vulgaris
antigliadin antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓celiac disease
antihistone antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓drug-induced SLE
,anti-IgG antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatoid arthritis
antimitochondrial antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓primary biliary
cirrhosis
antineutrophil antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓vasculitis
antiplatelet antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓idiopathic
thrombocytopenic purpura
arachnodactyly - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Marfan's syndrome
Argyll-Robertson pupil - diagnosis? ------- ✔ CORRECT ANSWER ✓✓neurosyphilis
Arnold-Chiari malformation ------- ✔ CORRECT ANSWER ✓✓cerebellar tonsillar herniation
Aschoff bodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatic fever
atrophy of the mammillary bodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Wernicke's
encephalopathy
Auer rods - diagnosis? ------- ✔ CORRECT ANSWER ✓✓acute myelogenous leukemia (especially
promyelocytic type)
autosplenectomy - diagnosis? ------- ✔ CORRECT ANSWER ✓✓sickle cell anemia
,Babinski's sign is associated with what? ------- ✔ CORRECT ANSWER ✓✓UMN lesion
"bamboo spine" on x-ray ------- ✔ CORRECT ANSWER ✓✓ankylosing spondylitis
basophilic stippling of RBCs - diagnosis? ------- ✔ CORRECT ANSWER ✓✓lead poisoning
defective dystrophin, less severe than Duchenne's ------- ✔ CORRECT ANSWER ✓✓Becker's
muscular dystrophy
LMN CN VII palsy ------- ✔ CORRECT ANSWER ✓✓Bell's palsy
Bence Jones proteins - possible diagnoses?
- in each case, what are the proteins? ------- ✔ CORRECT ANSWER ✓✓multiple myeloma - kappa
or lambda light chains
Waldenstrom's macroglobulinemia - IgM
IgA nephropathy - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Berger's disease
Bernard-Soulier disease - what is the defect? ------- ✔ CORRECT ANSWER ✓✓defect in platelet
adhesion
bilateral hilar adenopathy, uveitis - diagnosis? ------- ✔ CORRECT ANSWER ✓✓sarcoidosis
Birbeck granules on EM - diagnosis? ------- ✔ CORRECT ANSWER ✓✓histiocytosis X (eosinophilic
granuloma)
, bloody tap on LP - diagnosis? ------- ✔ CORRECT ANSWER ✓✓subarachnoid hemorrhage
"blue bloater" ------- ✔ CORRECT ANSWER ✓✓chronic bronchitis
blue-domed cysts - diagnosis? ------- ✔ CORRECT ANSWER ✓✓fibrocystic change of the breast
blue sclera - diagnosis? ------- ✔ CORRECT ANSWER ✓✓osteogenesis imperfecta
boot-shaped heart on x-ray - possible diagnoses? ------- ✔ CORRECT ANSWER ✓✓tetralogy of
Fallot or RVH
Bouchard's nodes - diagnosis?
- where are they located?
- why do they occur? ------- ✔ CORRECT ANSWER ✓✓osteoarthritis - on PIP secondary to
osteophytes
boutonniere deformity - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatoid arthritis
branching rods in oral infection - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Actinomyces israelii
"brown tumor" of bone - possible diagnoses?
- what causes the brown color? ------- ✔ CORRECT ANSWER ✓✓hyperparathyroidism or osteitis
fibrosa cystica (von Recklinghausen's disease)
- color is due to hemorrhage in cysts
X-linked agammaglobulinemia ------- ✔ CORRECT ANSWER ✓✓Bruton's disease
often precedes squamous cell carcinoma ------- ✔ CORRECT ANSWER ✓✓actinic keratosis
primary adrenocortical deficiency ------- ✔ CORRECT ANSWER ✓✓Addison's disease
polyostotic fibrous dysplasia, precocious puberty, cafe-au-lait spots, short stature, young girls -
diagnosis? ------- ✔ CORRECT ANSWER ✓✓Albright's syndrome
hereditary nephritis with nerve deafness ------- ✔ CORRECT ANSWER ✓✓Alport's syndrome
anti-basement membrane antibodies - diagnosis? ------- ✔ CORRECT ANSWER
✓✓Goodpasture's syndrome
anticentromere antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓scleroderma (CREST)
anti-double-stranded DNA antibodies (ANA antibodies) - diagnosis?
- what hypersensitivity type? ------- ✔ CORRECT ANSWER ✓✓SLE - type III hypersensitivity
anti-epithelial cell antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓pemphigus vulgaris
antigliadin antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓celiac disease
antihistone antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓drug-induced SLE
,anti-IgG antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatoid arthritis
antimitochondrial antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓primary biliary
cirrhosis
antineutrophil antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓vasculitis
antiplatelet antibodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓idiopathic
thrombocytopenic purpura
arachnodactyly - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Marfan's syndrome
Argyll-Robertson pupil - diagnosis? ------- ✔ CORRECT ANSWER ✓✓neurosyphilis
Arnold-Chiari malformation ------- ✔ CORRECT ANSWER ✓✓cerebellar tonsillar herniation
Aschoff bodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatic fever
atrophy of the mammillary bodies - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Wernicke's
encephalopathy
Auer rods - diagnosis? ------- ✔ CORRECT ANSWER ✓✓acute myelogenous leukemia (especially
promyelocytic type)
autosplenectomy - diagnosis? ------- ✔ CORRECT ANSWER ✓✓sickle cell anemia
,Babinski's sign is associated with what? ------- ✔ CORRECT ANSWER ✓✓UMN lesion
"bamboo spine" on x-ray ------- ✔ CORRECT ANSWER ✓✓ankylosing spondylitis
basophilic stippling of RBCs - diagnosis? ------- ✔ CORRECT ANSWER ✓✓lead poisoning
defective dystrophin, less severe than Duchenne's ------- ✔ CORRECT ANSWER ✓✓Becker's
muscular dystrophy
LMN CN VII palsy ------- ✔ CORRECT ANSWER ✓✓Bell's palsy
Bence Jones proteins - possible diagnoses?
- in each case, what are the proteins? ------- ✔ CORRECT ANSWER ✓✓multiple myeloma - kappa
or lambda light chains
Waldenstrom's macroglobulinemia - IgM
IgA nephropathy - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Berger's disease
Bernard-Soulier disease - what is the defect? ------- ✔ CORRECT ANSWER ✓✓defect in platelet
adhesion
bilateral hilar adenopathy, uveitis - diagnosis? ------- ✔ CORRECT ANSWER ✓✓sarcoidosis
Birbeck granules on EM - diagnosis? ------- ✔ CORRECT ANSWER ✓✓histiocytosis X (eosinophilic
granuloma)
, bloody tap on LP - diagnosis? ------- ✔ CORRECT ANSWER ✓✓subarachnoid hemorrhage
"blue bloater" ------- ✔ CORRECT ANSWER ✓✓chronic bronchitis
blue-domed cysts - diagnosis? ------- ✔ CORRECT ANSWER ✓✓fibrocystic change of the breast
blue sclera - diagnosis? ------- ✔ CORRECT ANSWER ✓✓osteogenesis imperfecta
boot-shaped heart on x-ray - possible diagnoses? ------- ✔ CORRECT ANSWER ✓✓tetralogy of
Fallot or RVH
Bouchard's nodes - diagnosis?
- where are they located?
- why do they occur? ------- ✔ CORRECT ANSWER ✓✓osteoarthritis - on PIP secondary to
osteophytes
boutonniere deformity - diagnosis? ------- ✔ CORRECT ANSWER ✓✓rheumatoid arthritis
branching rods in oral infection - diagnosis? ------- ✔ CORRECT ANSWER ✓✓Actinomyces israelii
"brown tumor" of bone - possible diagnoses?
- what causes the brown color? ------- ✔ CORRECT ANSWER ✓✓hyperparathyroidism or osteitis
fibrosa cystica (von Recklinghausen's disease)
- color is due to hemorrhage in cysts
X-linked agammaglobulinemia ------- ✔ CORRECT ANSWER ✓✓Bruton's disease
