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USMLE Step 1 Pharm – Complete Exam Study Guide 2026/2027 with Verified Answers | Newest Version. A+

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USMLE Step 1 Pharm – Complete Exam Study Guide 2026/2027 with Verified Answers | Newest Version. A+

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USMLE Step 1 Pharm-Complete Exam Study
Guide 2026/2027 with Verified Answers |
Newest Version. A+

-dronate ------- ✔ CORRECT ANSWER ✓✓Bisphosphonate drug. Bone resorption inhibitor.
Osteoporosis, Paget's, Hypercalcemia



Acarbose ------- ✔ CORRECT ANSWER ✓✓Alpha-glucosidase inhibitor. Blocks saccharide
degradation and thus glucose absorption by gut. Causes bloating.



Miglitol ------- ✔ CORRECT ANSWER ✓✓Alpha-glucosidase inhibitor. Blocks saccharide
degradation and thus glucose absorption by gut. Causes bloating.



Mifepristone ------- ✔ CORRECT ANSWER ✓✓Progesterone antagonist, Abortion, keep mi vagina
pristine



Danazol ------- ✔ CORRECT ANSWER ✓✓Androgen that blocks FSH, LH. Endometriosis.



Ergocalciferol ------- ✔ CORRECT ANSWER ✓✓Vitamin D



Finasteride ------- ✔ CORRECT ANSWER ✓✓5 alpha reductase inhibitor. Blocks DHT formation,
baldness, BPH.



Fludrocortisone ------- ✔ CORRECT ANSWER ✓✓Mineralocorticoid agonist. Adrenal
insufficiency.

, Glipizide ------- ✔ CORRECT ANSWER ✓✓Sulfonylurea. Block ATP K channels to promote insulin
release. Helps insulin glide out of beta cells



Glimepiride ------- ✔ CORRECT ANSWER ✓✓Sulfonylurea. Block ATP K channels to promote
insulin release. Helps insulin glide out of beta cells



Glyburide ------- ✔ CORRECT ANSWER ✓✓Sulfonylurea. Block ATP K channels to promote insulin
release. Helps insulin glide out of beta cells



Aspart ------- ✔ CORRECT ANSWER ✓✓Short-term insulin



Glulisine ------- ✔ CORRECT ANSWER ✓✓Short-term insulin



Lispro ------- ✔ CORRECT ANSWER ✓✓Short-term insulin



Insulin NPH ------- ✔ CORRECT ANSWER ✓✓Medium length insulin.



Glargine ------- ✔ CORRECT ANSWER ✓✓Long term insulin. Quite glarging around glucose, this
insulin is determined!



Determir ------- ✔ CORRECT ANSWER ✓✓Long term insulin. Quite glarging around glucose, this
insulin is determined!



Metformin ------- ✔ CORRECT ANSWER ✓✓Decrease hepatic glucose output. Prevents
formation of glucose



Methimazole ------- ✔ CORRECT ANSWER ✓✓Thyroid hormone synthesis inhibitor.

,Octreotide ------- ✔ CORRECT ANSWER ✓✓Blocks GH, IGF-1, Serotonin, Gastroactive peptides



Oxytocin ------- ✔ CORRECT ANSWER ✓✓Contracts uterus. Induce labor, stop uterine bleeding.
Promote lactation.



Pegvisomant ------- ✔ CORRECT ANSWER ✓✓GH antagonist. Acromegaly. Peg down your height!



Pioglitazone ------- ✔ CORRECT ANSWER ✓✓Sensitizes muscle and adipose to insulin. Gets
muscle and adipose in the "zone" to accept insulin.



Risoglitazone ------- ✔ CORRECT ANSWER ✓✓Sensitizes muscle and adipose to insulin. Gets
muscle and adipose in the "zone" to accept insulin.



Pramlintide ------- ✔ CORRECT ANSWER ✓✓Amylin analog. Slows gastric emptying and makes
you feel full. Less glycemia after meals. Pram down all the food you want, your body wont
absorb the glucose.



Raloxifene ------- ✔ CORRECT ANSWER ✓✓Bone resorption inhibitor. Estrogen agonist selective
for bone. Relax bone, you don't need to degrade, raloxifene is here.



Repaglinide ------- ✔ CORRECT ANSWER ✓✓Stimulates insulin release. Also has the glide like
sulfonylurea. Helps insulin glide out of beta cells.



Nateglinide ------- ✔ CORRECT ANSWER ✓✓Stimulates insulin release. Also has the glide like
sulfonylurea. Helps insulin glide out of beta cells.

, Sitagliptin ------- ✔ CORRECT ANSWER ✓✓DPP4 inhibitor, enhances incretin (GLP-1) action,
which enhances insulin secretion, muscle/fat uptake, decreases glucagon secretion.



Teriparatide ------- ✔ CORRECT ANSWER ✓✓PTH, postmenopausal women. May cause
osteosarcoma



-thromycin ------- ✔ CORRECT ANSWER ✓✓Macrolide. 50S inhibitor.



Aztreonam ------- ✔ CORRECT ANSWER ✓✓Monobactam. Pseudomonas and enterobacteriae



Caspofungin ------- ✔ CORRECT ANSWER ✓✓Antifungal that inhibits fungal cell wall synthesis



Cephalexin ------- ✔ CORRECT ANSWER ✓✓1st gen cephalosporin



Ceftriaxone ------- ✔ CORRECT ANSWER ✓✓3rd gen cephalosporin: pneumonia, gonorrhea,
otitis media



Cefepime ------- ✔ CORRECT ANSWER ✓✓4th gen cephalosporin. Citrobacter, enterobacter



-floxacin ------- ✔ CORRECT ANSWER ✓✓Fluoroquinolones,topo2 inhibitor,
tendionopathy/arthropathy



Clindamycin ------- ✔ CORRECT ANSWER ✓✓50s inhibitor. Causes enterocolitis



Doxycycline ------- ✔ CORRECT ANSWER ✓✓30S inhibitor. Teeth discoloration, photosensitivity.
Intracellular bugs

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