USMLE STEP 1 Review &
Memorize
developmental milestones (0-12 mo)
"Parents Start Observing"
motor:
-reflexes gone
-lift head (1m), roll/sit (6m), crawl (8m), stand (10m), walk (12-18m)
-pincer grasp (10m)
social
-social smile (2m)
verbal/cognitive
-object perm (9m)
-mama, dada (10m)
developmental milestones (12-36 mo)
"Child Rearing Working"
motor:
-first steps (12m)
-cubes stacked (age x3)
social:
-parallel play (24-36m)
-rapproachement (24m)
verbal/cog
-200 words (2y)
-2 word sentences
developmental milestones (3-5 yr)
,"Don't Forget, they're still Learning"
motor:
-tricycle (3y)
-stick figure draw (4y)
-hop on one foot (4y)
social
-cooperative play (4y)
verbal/cog:
-1000 words (3y)
-complete sentences (4y)
-story telling (4y)
lymph node drainage, upper
cervical: head & neck
hilar: lungs
mediastinal: trachea & esophagus
axillary: upper limb, breast, skin above umbilicus
lymph node drainage, middle
celiac: liver. stomach, spleen, upper duodenum
superior mesenteric: lower duodenum, jejunum, colon to splenic flexure
inferior mesenteric: colon from splenic flexure to upper rectum
lymph node drainage, lower
internal iliac: lower rectum to anal canal (above pectinate line), bladder, vagina (middle third),
cervix, prostate
para-aortic: testes, ovaries, kidneys, uterus
superficial inguinal: anal canal (below pectinate line), skin below umbilicus (except popliteal
,area), scrotum, vulva
popliteal: dorsolateral foot, posterior calf
lymphatic drainage
right lymphatic duct drains right side of body above diaphragm
thoracic duct drains everything else into jxn of L subclavian vein & internal jugular vein
encapsulated organisms whose infection incidence increases with decreased B cells or
splenectomy
"Please SHINE my SKiS"
Pseudomonas aeruginosa
Strep pneumoniae
Haemophilus Influenzae type b
Neisseria meningitidis
Escherichia coli
Salmonella spp.
Klebsiella pneumoniae
Group B Streptococci
HLA associated diseases, A3
hemochromatosis
HLA associated diseases, B8
Addison disease
myasthenia gravis
HLA associated diseases, B27
"PAIR", seronegative arthropathies
Psoriatic arthritis
Ankylosing spondylitis
IBD-associated arthritis
Reactive arthritis (Reiter syndrome)
HLA associated diseases, DQ2/DQ8
, "I ate (8) too (2) much gluten at Dairy Queen"
celiac disease
HLA associated diseases, DR2
multiple sclerosis
hay fever
SLE
Goodpasture syndrome
HLA associated diseases, DR3
diabetes mellitus type I
SLE
graves disease
Hashimoto thyroiditis
Addison disease
HLA associated diseases, DR4
"there are 4 walls in a rheum (room)"
Rheumatoid arthritis
diabetes mellitus type I
Addison disease
HLA associated diseases, DR5
pernicious anemia --> vit B12 deficiency
Hashimoto thyroiditis
cytokines secreted by MACs
IL-1
IL-6
IL-8
IL-12
TNF-α
cytokines, IL-1
-osteoclast activating factor
-causes fever, acute inflamm
-activates endothelium to express adhesion molec
-induces chemokine secretion to recruit RBCs
Memorize
developmental milestones (0-12 mo)
"Parents Start Observing"
motor:
-reflexes gone
-lift head (1m), roll/sit (6m), crawl (8m), stand (10m), walk (12-18m)
-pincer grasp (10m)
social
-social smile (2m)
verbal/cognitive
-object perm (9m)
-mama, dada (10m)
developmental milestones (12-36 mo)
"Child Rearing Working"
motor:
-first steps (12m)
-cubes stacked (age x3)
social:
-parallel play (24-36m)
-rapproachement (24m)
verbal/cog
-200 words (2y)
-2 word sentences
developmental milestones (3-5 yr)
,"Don't Forget, they're still Learning"
motor:
-tricycle (3y)
-stick figure draw (4y)
-hop on one foot (4y)
social
-cooperative play (4y)
verbal/cog:
-1000 words (3y)
-complete sentences (4y)
-story telling (4y)
lymph node drainage, upper
cervical: head & neck
hilar: lungs
mediastinal: trachea & esophagus
axillary: upper limb, breast, skin above umbilicus
lymph node drainage, middle
celiac: liver. stomach, spleen, upper duodenum
superior mesenteric: lower duodenum, jejunum, colon to splenic flexure
inferior mesenteric: colon from splenic flexure to upper rectum
lymph node drainage, lower
internal iliac: lower rectum to anal canal (above pectinate line), bladder, vagina (middle third),
cervix, prostate
para-aortic: testes, ovaries, kidneys, uterus
superficial inguinal: anal canal (below pectinate line), skin below umbilicus (except popliteal
,area), scrotum, vulva
popliteal: dorsolateral foot, posterior calf
lymphatic drainage
right lymphatic duct drains right side of body above diaphragm
thoracic duct drains everything else into jxn of L subclavian vein & internal jugular vein
encapsulated organisms whose infection incidence increases with decreased B cells or
splenectomy
"Please SHINE my SKiS"
Pseudomonas aeruginosa
Strep pneumoniae
Haemophilus Influenzae type b
Neisseria meningitidis
Escherichia coli
Salmonella spp.
Klebsiella pneumoniae
Group B Streptococci
HLA associated diseases, A3
hemochromatosis
HLA associated diseases, B8
Addison disease
myasthenia gravis
HLA associated diseases, B27
"PAIR", seronegative arthropathies
Psoriatic arthritis
Ankylosing spondylitis
IBD-associated arthritis
Reactive arthritis (Reiter syndrome)
HLA associated diseases, DQ2/DQ8
, "I ate (8) too (2) much gluten at Dairy Queen"
celiac disease
HLA associated diseases, DR2
multiple sclerosis
hay fever
SLE
Goodpasture syndrome
HLA associated diseases, DR3
diabetes mellitus type I
SLE
graves disease
Hashimoto thyroiditis
Addison disease
HLA associated diseases, DR4
"there are 4 walls in a rheum (room)"
Rheumatoid arthritis
diabetes mellitus type I
Addison disease
HLA associated diseases, DR5
pernicious anemia --> vit B12 deficiency
Hashimoto thyroiditis
cytokines secreted by MACs
IL-1
IL-6
IL-8
IL-12
TNF-α
cytokines, IL-1
-osteoclast activating factor
-causes fever, acute inflamm
-activates endothelium to express adhesion molec
-induces chemokine secretion to recruit RBCs
