NURS 5357 Neurobiology Exam 1 -
Updated Summer 25 Exam Questions
With Correct Detailed & Analyzed
Answers (VERIFIED Solutions)|updated
Exam 100% Accuracy ||ACTUAL EXAM
2026 TEST!! | 2026|2027
Graded A+
What are the three major hypotheses of psychosis and their
neurotransmitter networks? - ANSWERS-Dopamine theory - hyperactive
dopamine at D2 receptors in the mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative
symptoms of schizophrenia. - ANSWERS-The dopamine hypothesis of
schizophrenia consists of:
There is too much dopamine activity in the mesolimbic dopamine pathway,
which leads to positive symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine
pathway, which leads to negative symptoms (such as blunting of affect,
poverty of speech, anhedonia, and so on).
,What pathway is responsible for regulating dopamine in the hypothalamus
and affects the release of prolactin? - ANSWERS-Tuberoinfundibular
pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what
pathway? - ANSWERS-Nigrostriatal pathway
Brodmann's areas are differentiated by the: - ANSWERS-Cellular
architecture
All of the following are true about the hippocampus except that it: -
ANSWERS-Is disrupted by frontal lobotomy
Which of the following statements is true about the cerebellum: -
ANSWERS-Has been implicated in autism.
Cytokines are involved with all of the following except: - ANSWERS-
identifying T. pallidum
Which of the following is a possible explanation for schizophrenia: -
ANSWERS-Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders
include all of the following except: - ANSWERS-Changes in GR's
All of the following are plausible theories on the etiology of schizophrenia
except? - ANSWERS-Dopamine hypothesis
, Auditory hallucinations have been shown to activate which region on fMRI?
- ANSWERS-Superior temporal lobe
All of the following suggest white matter impairment in schizophrenia
except? - ANSWERS-Significantly reduced white matter volume
Evidence that GABA interneurons are impaired in schizophrenia -
ANSWERS-Reduced GAD67
All of the following support the reduced neuropil hypothesis except? -
ANSWERS-oligodendrocyte dysfunction
Evidence that schizophrenia is a biological disorder includes all of the
following except? - ANSWERS-Gliosis in the prefrontal cortex
Neurodevelopmental causes that could explain schizophrenia include
excessive amounts of all of the following except: - ANSWERS-Myelination
The NP's discuss a patient diagnosed with schizophrenia. The PMHNP
knows that which of the following groups of symptoms is most likely to be
categorized as "negative symptoms" of schizophrenia? - ANSWERS-
Blunted affect, poor rapport, lack of spontaneity
There is a genetic contribution to some, perhaps all, forms of
schizophrenia. In the case of monozygotic twins who have identical genetic
makeup, there is an approximately 50 percent chance for them to develop
schizophrenia. - ANSWERS-True
Princess, a 22-year-old female, presents with schizophrenia characterized
by the presence of positive, negative, cognitive, and affective symptoms.
Updated Summer 25 Exam Questions
With Correct Detailed & Analyzed
Answers (VERIFIED Solutions)|updated
Exam 100% Accuracy ||ACTUAL EXAM
2026 TEST!! | 2026|2027
Graded A+
What are the three major hypotheses of psychosis and their
neurotransmitter networks? - ANSWERS-Dopamine theory - hyperactive
dopamine at D2 receptors in the mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
Briefly explain the dopamine hypothesis of the positive and negative
symptoms of schizophrenia. - ANSWERS-The dopamine hypothesis of
schizophrenia consists of:
There is too much dopamine activity in the mesolimbic dopamine pathway,
which leads to positive symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine
pathway, which leads to negative symptoms (such as blunting of affect,
poverty of speech, anhedonia, and so on).
,What pathway is responsible for regulating dopamine in the hypothalamus
and affects the release of prolactin? - ANSWERS-Tuberoinfundibular
pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what
pathway? - ANSWERS-Nigrostriatal pathway
Brodmann's areas are differentiated by the: - ANSWERS-Cellular
architecture
All of the following are true about the hippocampus except that it: -
ANSWERS-Is disrupted by frontal lobotomy
Which of the following statements is true about the cerebellum: -
ANSWERS-Has been implicated in autism.
Cytokines are involved with all of the following except: - ANSWERS-
identifying T. pallidum
Which of the following is a possible explanation for schizophrenia: -
ANSWERS-Excessive pruning
Possible explanations for the role of thyroid hormone in mood disorders
include all of the following except: - ANSWERS-Changes in GR's
All of the following are plausible theories on the etiology of schizophrenia
except? - ANSWERS-Dopamine hypothesis
, Auditory hallucinations have been shown to activate which region on fMRI?
- ANSWERS-Superior temporal lobe
All of the following suggest white matter impairment in schizophrenia
except? - ANSWERS-Significantly reduced white matter volume
Evidence that GABA interneurons are impaired in schizophrenia -
ANSWERS-Reduced GAD67
All of the following support the reduced neuropil hypothesis except? -
ANSWERS-oligodendrocyte dysfunction
Evidence that schizophrenia is a biological disorder includes all of the
following except? - ANSWERS-Gliosis in the prefrontal cortex
Neurodevelopmental causes that could explain schizophrenia include
excessive amounts of all of the following except: - ANSWERS-Myelination
The NP's discuss a patient diagnosed with schizophrenia. The PMHNP
knows that which of the following groups of symptoms is most likely to be
categorized as "negative symptoms" of schizophrenia? - ANSWERS-
Blunted affect, poor rapport, lack of spontaneity
There is a genetic contribution to some, perhaps all, forms of
schizophrenia. In the case of monozygotic twins who have identical genetic
makeup, there is an approximately 50 percent chance for them to develop
schizophrenia. - ANSWERS-True
Princess, a 22-year-old female, presents with schizophrenia characterized
by the presence of positive, negative, cognitive, and affective symptoms.
