APHON Principles of Chemo and Biotherapy Exam
UPDATE/PRACTICE QUESTIONS AND CORRECT VERIFIED
ANSWERS(complete solutions)ASSURED SUCCESS/GRADED A+!!!
Define adjuvant chemotherapy- CORRECT ANSWER- The use of chemo after
another type of therapy, such as surgery, to treat residual disease or undetectable
metastasis.
- CORRECT ANSWER-
Define neoadjuvant chemotherapy When chemo is used
preoperatively to decrease tumor burden in order to make it easier to remove the
tumor surgically.
- CORRECT ANSWER-
Define sanctuary sites Sites within the body where tumor
cells sequester and are not easily reached by chemo such as the CNS
- CORRECT
What normal cells are most often effected by chemotherapy
ANSWER-
Hematopoietic, mucosal (mouth & GI), hair follicles
Why use chemotherapy - CORRECT ANSWER- To prevent cancer cells from
dividing, metastasizing, and ultimately causing the death of the patient
, Cure - CORRECT ANSWER-
To permanently eradicate the cancer
Control - CORRECT ANSWER-
To extend the length & QOL when cure is not
feasible or realistic
Biotherapy- CORRECT ANSWER- Targeted anticancer agents also known as
biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what -class
CORRECT ANSWER-
Biotherapy
- CORRECT ANSWER-
Monoclonal antibodies (MoAbs) are what class Biotherapy
- CORRECT ANSWER-
Define pharmacokinetics Study of drug absorption,
metabolism, and excretion
Define pharmacodynamics - CORRECT ANSWER- The concentration of the drug
in the body and how it produces a response
Palliation- CORRECT ANSWER-
Minimize pain and suffering during end of life
- CORRECT ANSWER-
Resting phase of cell cycle Gap 0 - cells not dividing
Postmitotic phase- CORRECT ANSWER- Gap 1 - enzymes needed for DNA
synthesis are produced, protein and RNA synthesis takes place (18 Hours)
UPDATE/PRACTICE QUESTIONS AND CORRECT VERIFIED
ANSWERS(complete solutions)ASSURED SUCCESS/GRADED A+!!!
Define adjuvant chemotherapy- CORRECT ANSWER- The use of chemo after
another type of therapy, such as surgery, to treat residual disease or undetectable
metastasis.
- CORRECT ANSWER-
Define neoadjuvant chemotherapy When chemo is used
preoperatively to decrease tumor burden in order to make it easier to remove the
tumor surgically.
- CORRECT ANSWER-
Define sanctuary sites Sites within the body where tumor
cells sequester and are not easily reached by chemo such as the CNS
- CORRECT
What normal cells are most often effected by chemotherapy
ANSWER-
Hematopoietic, mucosal (mouth & GI), hair follicles
Why use chemotherapy - CORRECT ANSWER- To prevent cancer cells from
dividing, metastasizing, and ultimately causing the death of the patient
, Cure - CORRECT ANSWER-
To permanently eradicate the cancer
Control - CORRECT ANSWER-
To extend the length & QOL when cure is not
feasible or realistic
Biotherapy- CORRECT ANSWER- Targeted anticancer agents also known as
biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what -class
CORRECT ANSWER-
Biotherapy
- CORRECT ANSWER-
Monoclonal antibodies (MoAbs) are what class Biotherapy
- CORRECT ANSWER-
Define pharmacokinetics Study of drug absorption,
metabolism, and excretion
Define pharmacodynamics - CORRECT ANSWER- The concentration of the drug
in the body and how it produces a response
Palliation- CORRECT ANSWER-
Minimize pain and suffering during end of life
- CORRECT ANSWER-
Resting phase of cell cycle Gap 0 - cells not dividing
Postmitotic phase- CORRECT ANSWER- Gap 1 - enzymes needed for DNA
synthesis are produced, protein and RNA synthesis takes place (18 Hours)
