BCPS Exam || 100% Errorless.
____ is the most appropriate answer because there are no drug-drug interactions or
contraindications / cautions in HIV correct answers Bictegravir
n patients with persistent neutropenic fever despite anti-pseudomonal coverage, what should be
considered? correct answers empiric antifungal therapy should be considered after 4 - 10 days
electrocautery correct answers Which of the following therapies is most likely to result in a
resolution rate which approaches 100% in patients w/ external anogenital warts.?
preferred therapy for CMV retinitis? correct answers Ganciclovir intravitreal injections plus
valganciclovir oral
bacterial vaginosis recommended treatment correct answers clindamycin or metronidazole
(i.e. Clindamycin 300 mg orally twice daily for 7 days)
recommended treatment regimen for pelvic inflammatory disease correct answers Ceftriaxone
250 mg intramuscularly x 1 dose plus doxycycline 100 mg orally twice daily for 14 days
vulvovaginal candidiasis teeatment correct answers Clindamycin cream 2%, 5 g intravaginally at
bedtime for 7 days
MedWatch correct answers preferred route for healthcare professionals and patients to report
suspected adverse events to the FDA
FDA Form 3500A correct answers mechanism for reporting suspected adverse events, but is
reserved for use by user-facilities, importers, distributors, and manufacturers
-reporting errors related to vaccines correct answers ISMP VERP and VAERS
viral rhinosinusitis sx duration correct answers -peak at 3 days and may persist longer than 14
days but usually decreases in severity by 10 days
-watchful waiting is recommended to avoid overuse of antibiotics as episodes are often self-
limited
Malignant external otitis treatment correct answers - predominantly caused by Pseudomonas
aeruginosa
-antipseudomonal antimicrobials are considered the mainstay of therapy.
Fidaxomicin correct answers -associated with decreased recurrence of Clostridioides difficile
likely owing to its narrow spectrum and minimal effect on normal colonic flora
, duration of initial therapy for CDI? correct answers 10 days with oral vancomycin or
fidaxomicin
MRSA PCR correct answers -well-recognized tool for antimicrobial de-escalation as part of
stewardship initiatives given the high negative predictive value
MRSA nasal culture correct answers -used for surveillance and is not employed as a stewardship
tool
Procalcitonin correct answers -useful in differentiating between viral and bacterial etiologies
-chronic kidney disease may cause an artificially high level leading to questionable interpretation
and potential continuation of inappropriate antimicrobials
Asymptomatic candiduria correct answers -common among hospitalized patients with an
indwelling urinary catheter and treatment is nt is not warranted
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (EVG/c/FTC/TAF) correct answers
Elvitegravir is only available in single-tablet regimen form; either as EVG/c/FTC/TAF or
EVG/c/FTC/TDF. Therefore, it is not possible to stock the single agents and "break up" the
patient's regimen
Waterfall plot correct answers -Waterfall plot is ideal to represent secondary objectives.
BRAF Mutation correct answers BRAF mutation confers resistance to EGFR inhibitors; Anti-
EGFR therapies should be avoided in KRAS WT and BRAF mutant mCRC unless given in
combination with BRAF inhibitor
Palbociclib correct answers -FDA approval for male breast cancer in combination with an
aromatase inhibitor or fulvestrant for men with hormone receptor-positive (HR+), human
epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer
Atezolizumab combined with nab-paclitaxel correct answers -in breast CA is based on the PD-
L1 expression on tumor-infiltrating immune cells
Olaparib correct answers -Breast cancer
-metastatic,
-HER2-negative -germline BRCA-mutated (gBRCAm)
Tvec indication correct answers -second-line setting
- patients with skin involvement
-not metastatic
platinum-sensitive disease correct answers =/> 6 months
<6 months correct answers platinum refractory
____ is the most appropriate answer because there are no drug-drug interactions or
contraindications / cautions in HIV correct answers Bictegravir
n patients with persistent neutropenic fever despite anti-pseudomonal coverage, what should be
considered? correct answers empiric antifungal therapy should be considered after 4 - 10 days
electrocautery correct answers Which of the following therapies is most likely to result in a
resolution rate which approaches 100% in patients w/ external anogenital warts.?
preferred therapy for CMV retinitis? correct answers Ganciclovir intravitreal injections plus
valganciclovir oral
bacterial vaginosis recommended treatment correct answers clindamycin or metronidazole
(i.e. Clindamycin 300 mg orally twice daily for 7 days)
recommended treatment regimen for pelvic inflammatory disease correct answers Ceftriaxone
250 mg intramuscularly x 1 dose plus doxycycline 100 mg orally twice daily for 14 days
vulvovaginal candidiasis teeatment correct answers Clindamycin cream 2%, 5 g intravaginally at
bedtime for 7 days
MedWatch correct answers preferred route for healthcare professionals and patients to report
suspected adverse events to the FDA
FDA Form 3500A correct answers mechanism for reporting suspected adverse events, but is
reserved for use by user-facilities, importers, distributors, and manufacturers
-reporting errors related to vaccines correct answers ISMP VERP and VAERS
viral rhinosinusitis sx duration correct answers -peak at 3 days and may persist longer than 14
days but usually decreases in severity by 10 days
-watchful waiting is recommended to avoid overuse of antibiotics as episodes are often self-
limited
Malignant external otitis treatment correct answers - predominantly caused by Pseudomonas
aeruginosa
-antipseudomonal antimicrobials are considered the mainstay of therapy.
Fidaxomicin correct answers -associated with decreased recurrence of Clostridioides difficile
likely owing to its narrow spectrum and minimal effect on normal colonic flora
, duration of initial therapy for CDI? correct answers 10 days with oral vancomycin or
fidaxomicin
MRSA PCR correct answers -well-recognized tool for antimicrobial de-escalation as part of
stewardship initiatives given the high negative predictive value
MRSA nasal culture correct answers -used for surveillance and is not employed as a stewardship
tool
Procalcitonin correct answers -useful in differentiating between viral and bacterial etiologies
-chronic kidney disease may cause an artificially high level leading to questionable interpretation
and potential continuation of inappropriate antimicrobials
Asymptomatic candiduria correct answers -common among hospitalized patients with an
indwelling urinary catheter and treatment is nt is not warranted
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (EVG/c/FTC/TAF) correct answers
Elvitegravir is only available in single-tablet regimen form; either as EVG/c/FTC/TAF or
EVG/c/FTC/TDF. Therefore, it is not possible to stock the single agents and "break up" the
patient's regimen
Waterfall plot correct answers -Waterfall plot is ideal to represent secondary objectives.
BRAF Mutation correct answers BRAF mutation confers resistance to EGFR inhibitors; Anti-
EGFR therapies should be avoided in KRAS WT and BRAF mutant mCRC unless given in
combination with BRAF inhibitor
Palbociclib correct answers -FDA approval for male breast cancer in combination with an
aromatase inhibitor or fulvestrant for men with hormone receptor-positive (HR+), human
epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer
Atezolizumab combined with nab-paclitaxel correct answers -in breast CA is based on the PD-
L1 expression on tumor-infiltrating immune cells
Olaparib correct answers -Breast cancer
-metastatic,
-HER2-negative -germline BRCA-mutated (gBRCAm)
Tvec indication correct answers -second-line setting
- patients with skin involvement
-not metastatic
platinum-sensitive disease correct answers =/> 6 months
<6 months correct answers platinum refractory
