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NR 546 Psychopharmacology Week 5 Review – COMPLETE EXAM STUDY GUIDE 2026/2027 WITH VERIFIED CORRECT ANSWERS || GUARANTEED PASS | NEWEST VERSION

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NR 546 Psychopharmacology Week 5 Review – COMPLETE EXAM STUDY GUIDE 2026/2027 WITH VERIFIED CORRECT ANSWERS || GUARANTEED PASS | NEWEST VERSION

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NR 546 Week 5- EXAM STUDY GUIDE
2026/2027 COMPLETE QUESTIONS
WITH VERIFIED CORRECT ANSWERS ||
100% GUARANTEED PASS NEWEST
VERSION

Bipolar Diseased is diagnosed when

one or more episodes of mania or hypomania with a history of one or more major depressive
episodes

Use of antidepressants in the treatment of bipolar disease

may precipitate a manic episode or induce rapid-cycling, used cautiously and never as
monotherapy. should be combined with a mood stabilizer to prevent the onset of a hypomanic
or manic episode.

Bipolar I vs Bipolar II vs Cyclothymia

Mood-related symptoms in BP may be characterized as having either too little positive affect
or too much negative affect

MDD can be mapped to specific malfunctioning brain circuits:

Prefrontal Cortex (PFC)

PFC & Amygdala

Striatum

Nucleus Accumbens

Hypothalamus

Prefrontal Cortex (PFC)

Concentration

, Mental fatigue

Mood

PFC & Amygdala

Guilt, suicidality, worthlessness

Striatum

Physical fatigue

Nucleus Accumbens

Pleasure interests

Hypothalamus

Sleep, appetite

MOA: SSRI, SNRI, NDRI

Selective Serotonin Reuptake Inhibitors (SSRIs) inhibit 5-HT reuptake

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

inhibit 5-HT reuptake

inhibit NE reuptake (increase energy, focus)

increase DA in prefrontal cortex (increase cognition)

Norepinephrine Dopamine Reuptake Inhibitors (NDRI)

inhibit DA reuptake (increase alertness, motivation)

inhibit NE reuptake (increase energy)

Adverse Effects: SSRI, SNRI, NDRI

Selective Serotonin Reuptake Inhibitors (SSRIs): diarrhea, headache, weight gain, sexual side
effects

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): elevated blood pressure, anxiety,
insomnia,

constipation

Norepinephrine Dopamine Reuptake Inhibitors (NDRI): agitation headache dry mouth
constipation weight loss

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