PHARMACOTHERAPEUTICS FOR
ADVANCED PRACTICE NURSE
PRESCRIBERS QUESTIONS AND
ANSWERS WITH CORRECT
SOLUTIONS UPDATE 2026
When and what do prescriptions needs to be written - CORRECT ANSWES -- Medical
devices, controlled drugs, and legend drugs
Based on the patients below, who is at high risk for experiencing an adverse drug
reaction?
1) 32-year old male
2) 22- year told female
3) 3 month old female
4)48 year old male - CORRECT ANSWES -- 3 month old
Why are infants and babies are a higher risk of adverse drug reactions? - CORRECT
ANSWES -- lack of safety and efficacy studies in pediatric populations
Why are elderly at high risk of adverse drug reactions? - CORRECT ANSWES -- Age-
related decrease in renal function
The type of adverse drug reaction that is idiosyncratic when a drug is given in the usual
therapeutic dose is type - CORRECT ANSWES -- Type B
Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen - CORRECT ANSWES -- Its narrow therapeutic index
What type of reaction occurs after a medication is used? - CORRECT ANSWES -- Type
IV
If neutropenia occurs after the use of a topical medication, what type of reaction is
neutropenia characterized as - CORRECT ANSWES -- Cytotoxic hypersensitivyt
reaction
What type of reaction is anaphylactic shock? - CORRECT ANSWES -- Type 1 Reaction;
Also known as an immediate hypersensitivity reaction
,What time of reaction is someone using a corticosteroid at risk for? - CORRECT
ANSWES -- Type C
Why do immunomodulators such as azathioprine cause a delayed reaction (type D
reaction) - CORRECT ANSWES -- because they are carcinogens
An example of a first-dose reaction that may occur includes:
1. Orthostatic hypotension that does not occur with repeated doses
2. Purple glove syndrome with phenytoin use
3. Hemolytic anemia from ceftriaxone use
4. Contact dermatitis from neomycin use - CORRECT ANSWES -- Orthostatic
hypotension that does not occur with repeated doses
Drugs that are prone to cause adverse drug reactions include - CORRECT ANSWES --
Insulins
US FDA MedWatch system is activated when: - CORRECT ANSWES -- An adverse
even or serious problem occurs with a medication that is not already identified on the
label
The Vaccine Adverse Events Reporting System is - CORRECT ANSWES -- A voluntary
reporting system that healthcare providers or consumers may use to report vaccine
adverse events
What is pharmacoeconomics? - CORRECT ANSWES -- The analysis of the cost and
consequences of any health-care related treatment or services
The direct cost of drug therapy includes - CORRECT ANSWES -- Pain and suffering
due to inadequate drug therapy
Indirect costs associated with drug therapy include? - CORRECT ANSWES -- Loss of
wages while undergoing drug therapy
The intangible cost of drug therapy include? - CORRECT ANSWES -- Inconvenience,
pain, and suffering incurred with therapy
What is it called when a pharmacoeconomic analysis takes place regarding two similar
treatments for a disease? - CORRECT ANSWES -- Cost-minimization analysis
Cost-effectiveness analysis compares two or more treatments or programs that are: -
CORRECT ANSWES -- not necessarily therapeutically equivalent
When the cost of a specific treatment or intervention are calculated and then compared
with the dollar value of the benefit received it is referred to as - CORRECT ANSWES --
Cost-benefit analysis
, What is a two-tiered prescription benefit plan? - CORRECT ANSWES -- Higher co-pay
for brand name drugs than for generic drugs
When a provider proscribes a less expensive drug what does it increase and how? -
CORRECT ANSWES -- Compliance & by decreasing the financial burden set on the
patient
When someone asks to explain what a coverage plan means, such as a Medicare plan,
what should the NP do? - CORRECT ANSWES -- Refer the patient to a Medicare
Specialist at his insurance carrier to explain the benefits of his insurance
Digoxin levels need to be monitored closely when the following medication is started:
1. Loratadine
2. Diphenhydramine
3. Ipratropium
4. Albuterol - CORRECT ANSWES -- Albuterol
Patients with pheochromocytoma should avoid what class of drug and why? -
CORRECT ANSWES -- Beta-2-Agonists as it causes hypertensive crisis
What medications should be use cautiously with African American men with moderate
persistent asthma? - CORRECT ANSWES -- Salmeterol - It is an inhaled long-acting
beta agonist; studies showed increase of respiratory and asthma related deaths in
African Americans
LTBA's received a black box warning due to? - CORRECT ANSWES -- increased risk of
asthma related deaths
What is the bronchodilator of choice for those taking propranolol? - CORRECT
ANSWES -- Ipratropium
Life-style management for those taking theophylline. - CORRECT ANSWES -- self-
monitoring of respiratory status w. peak flowmeter; stop smoking; voice environmental
triggers for asthma
What does Tiotropium bromide treat (Spiriva)? - CORRECT ANSWES -- COPD
the medication is an inhaled anticholinergic
How often should Beclomethasone be used for someone with asthma? - CORRECT
ANSWES -- Daily
What are some side effects if montelukast (singular)? - CORRECT ANSWES --
Aggression, anxiety, depression, and or suicidal thoughts
ADVANCED PRACTICE NURSE
PRESCRIBERS QUESTIONS AND
ANSWERS WITH CORRECT
SOLUTIONS UPDATE 2026
When and what do prescriptions needs to be written - CORRECT ANSWES -- Medical
devices, controlled drugs, and legend drugs
Based on the patients below, who is at high risk for experiencing an adverse drug
reaction?
1) 32-year old male
2) 22- year told female
3) 3 month old female
4)48 year old male - CORRECT ANSWES -- 3 month old
Why are infants and babies are a higher risk of adverse drug reactions? - CORRECT
ANSWES -- lack of safety and efficacy studies in pediatric populations
Why are elderly at high risk of adverse drug reactions? - CORRECT ANSWES -- Age-
related decrease in renal function
The type of adverse drug reaction that is idiosyncratic when a drug is given in the usual
therapeutic dose is type - CORRECT ANSWES -- Type B
Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen - CORRECT ANSWES -- Its narrow therapeutic index
What type of reaction occurs after a medication is used? - CORRECT ANSWES -- Type
IV
If neutropenia occurs after the use of a topical medication, what type of reaction is
neutropenia characterized as - CORRECT ANSWES -- Cytotoxic hypersensitivyt
reaction
What type of reaction is anaphylactic shock? - CORRECT ANSWES -- Type 1 Reaction;
Also known as an immediate hypersensitivity reaction
,What time of reaction is someone using a corticosteroid at risk for? - CORRECT
ANSWES -- Type C
Why do immunomodulators such as azathioprine cause a delayed reaction (type D
reaction) - CORRECT ANSWES -- because they are carcinogens
An example of a first-dose reaction that may occur includes:
1. Orthostatic hypotension that does not occur with repeated doses
2. Purple glove syndrome with phenytoin use
3. Hemolytic anemia from ceftriaxone use
4. Contact dermatitis from neomycin use - CORRECT ANSWES -- Orthostatic
hypotension that does not occur with repeated doses
Drugs that are prone to cause adverse drug reactions include - CORRECT ANSWES --
Insulins
US FDA MedWatch system is activated when: - CORRECT ANSWES -- An adverse
even or serious problem occurs with a medication that is not already identified on the
label
The Vaccine Adverse Events Reporting System is - CORRECT ANSWES -- A voluntary
reporting system that healthcare providers or consumers may use to report vaccine
adverse events
What is pharmacoeconomics? - CORRECT ANSWES -- The analysis of the cost and
consequences of any health-care related treatment or services
The direct cost of drug therapy includes - CORRECT ANSWES -- Pain and suffering
due to inadequate drug therapy
Indirect costs associated with drug therapy include? - CORRECT ANSWES -- Loss of
wages while undergoing drug therapy
The intangible cost of drug therapy include? - CORRECT ANSWES -- Inconvenience,
pain, and suffering incurred with therapy
What is it called when a pharmacoeconomic analysis takes place regarding two similar
treatments for a disease? - CORRECT ANSWES -- Cost-minimization analysis
Cost-effectiveness analysis compares two or more treatments or programs that are: -
CORRECT ANSWES -- not necessarily therapeutically equivalent
When the cost of a specific treatment or intervention are calculated and then compared
with the dollar value of the benefit received it is referred to as - CORRECT ANSWES --
Cost-benefit analysis
, What is a two-tiered prescription benefit plan? - CORRECT ANSWES -- Higher co-pay
for brand name drugs than for generic drugs
When a provider proscribes a less expensive drug what does it increase and how? -
CORRECT ANSWES -- Compliance & by decreasing the financial burden set on the
patient
When someone asks to explain what a coverage plan means, such as a Medicare plan,
what should the NP do? - CORRECT ANSWES -- Refer the patient to a Medicare
Specialist at his insurance carrier to explain the benefits of his insurance
Digoxin levels need to be monitored closely when the following medication is started:
1. Loratadine
2. Diphenhydramine
3. Ipratropium
4. Albuterol - CORRECT ANSWES -- Albuterol
Patients with pheochromocytoma should avoid what class of drug and why? -
CORRECT ANSWES -- Beta-2-Agonists as it causes hypertensive crisis
What medications should be use cautiously with African American men with moderate
persistent asthma? - CORRECT ANSWES -- Salmeterol - It is an inhaled long-acting
beta agonist; studies showed increase of respiratory and asthma related deaths in
African Americans
LTBA's received a black box warning due to? - CORRECT ANSWES -- increased risk of
asthma related deaths
What is the bronchodilator of choice for those taking propranolol? - CORRECT
ANSWES -- Ipratropium
Life-style management for those taking theophylline. - CORRECT ANSWES -- self-
monitoring of respiratory status w. peak flowmeter; stop smoking; voice environmental
triggers for asthma
What does Tiotropium bromide treat (Spiriva)? - CORRECT ANSWES -- COPD
the medication is an inhaled anticholinergic
How often should Beclomethasone be used for someone with asthma? - CORRECT
ANSWES -- Daily
What are some side effects if montelukast (singular)? - CORRECT ANSWES --
Aggression, anxiety, depression, and or suicidal thoughts
