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ATI Pharmacology Review – Practice Questions with Accurate Answers & Explanations

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The ATI Pharmacology Review is a comprehensive study resource designed to help nursing students prepare for ATI pharmacology assessments. This guide includes clearly written, ATI-aligned practice questions with accurate answers and clear explanations based on current pharmacology standards. Topics covered include pharmacokinetics and pharmacodynamics, medication administration and safety, dosage calculations, high-alert medications, major drug classes, adverse effects, contraindications, drug interactions, and patient education. The review emphasizes clinical judgment and safe medication practices essential for exam success.

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Pharmacology ATI Review With
Correct Questions And Verified
Answers

Nursing Implications by Oral Route of Administration - correct answer.💖💖💖💖✔<<<<<-avoid
grapefruit juice

-in general, administer on an empty stomach (1 hr before meals, 2 hr after meals)

-use liquid form to facilitate swallowing whenever possible



Nursing Implications by Drop Instillation Route of Administration - correct
answer.💖💖💖💖✔<<<<<-side-lying

-place client supine with head positioned to allow medication to enter appropriate nasal passage

-instruct client to breathe through mouth, stay in supine position, and blowing nose for 5 min after drop
insertion

-dropped into center of conjunctival sac

-close eye to improve distribution of medication



needle sizes: subcutaneous - correct answer.💖💖💖💖✔<<<<<3/8 to 5/8, 25 to 27 gauge

(abdomen, upper hips/love handles, lateral upper arms)



needle sizes: Intramuscular - correct answer.💖💖💖💖✔<<<<<22 to 25 gauge, 1 to 1.5 inches

((ventrogluteal, deltoid, vastus lateralis (pediatrics))



needle sizes: Intravenous - correct answer.💖💖💖💖✔<<<<<surgical: 18 gauge

trauma: 16 gauge



actions to verify trough level - correct answer.💖💖💖💖✔<<<<<blod specimen obtained
immediately prior to the next dose of medication

,6 patient rights - correct answer.💖💖💖💖✔<<<<<patient, medication, dose, time, route,
documentation

(product, price, time, place for right person)



preventing med errors: assessment - correct answer.💖💖💖💖✔<<<<<ensure knowledge of
medication. use appropriate resources: drug handbooks, physicians desk reference, professional
journals



preventing med erros: implementation - correct answer.💖💖💖💖✔<<<<<avoid distractions during
medication preparation (poor lighting, noise, interruptions)



Safe IV Administration - correct answer.💖💖💖💖✔<<<<<-potassium chloride can cause serious
adverse reactions; should be delivered with an electronic infusion pump for dose control

-scissors or electric shaver for hair removal



maintaining patency of IV access - correct answer.💖💖💖💖✔<<<<<- do not stop continuous
infusion or or allow blood to back up into the catheter, clots can form

-flush intermittent IV catheters with appropriate solution after every med admin or every 8 to 12 hours



infiltration - correct answer.💖💖💖💖✔<<<<<stop infusion and remove catheter



extravasation (infiltration of vesicant/tissue-damaging medication) - correct
answer.💖💖💖💖✔<<<<<stop infusion and notify provider



hematoma - correct answer.💖💖💖💖✔<<<<<ecchymosis at site

-apply pressure after IV catheter removal



phebitis/thrombophebitis - correct answer.💖💖💖💖✔<<<<<edema, throbbing, burning, pain at
the site

- assess for palpable, hard mass above insertion site is a clinical manifestation of thrombophlebitis

, FDA risk to fetus medication categories:

(A is best, X is worst) - correct answer.💖💖💖💖✔<<<<<Category A: There is no evidence of risk to
fetus during pregnancy based on adequate and well-controlled studies.

Category B: There is no evidence of risk to animal fetuses based on studies, but there are no adequate
and well-controlled studies in pregnant women.

Category C: Adverse effects have been demonstrated on animal fetuses. There are no adequate and
well-controlled studies in pregnant women, but use of the medication during pregnancy may be
warranted based on the potential benefits.

D: adverse effects demonstrated on data from investigational or marketing experience

X: adverse effects demonstrated on animal and human fetuses



Glucocorticoids - correct answer.💖💖💖💖✔<<<<<background

- produced in adrenal cortex

-cortisol produce to regulate glucose in responce to stress

Exemplar

Prednisone

AE: increase dose causes Cushing's syndrome

Cushing's syndrome: fluid retention, HTN, weight gain, fat redistribution and truncal obesity, moon face,
buffalo hump, susceptibility to infection, hyperglycemia, osteoporosis, menstrual irregularities, thin
fragile skin, hirsutism

-concurrent use of glucocorticoids decrease anticoagulant effects of warfarin (warfarin is preg X med)



Addison's Disease - correct answer.💖💖💖💖✔<<<<<- hyperpigmentation

- hypoglycemia

- low blood pressure



potassium normal range 3.5 to 5.5 mEq/L millimoles

hyperkalemia - correct answer.💖💖💖💖✔<<<<<- can lower blood pressure

- causes:

kidney disease and failure

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