ASCP CG CERTIFICATION EXAM 2026 WITH 200 REAL EXAM QUESTIONS AND CORRECT ANSWERS | ASCP CG CERTIFICATION TEST | ASCP CYTOGENETICS TEST | NEW 2026/2027 UPDATE | GRADED A+.

ASCP CG CERTIFICATION EXAM 2026 WITH 200 REAL EXAM QUESTIONS AND CORRECT ANSWERS | ASCP CG CERTIFICATION TEST | ASCP CYTOGENETICS TEST | NEW 2026/2027 UPDATE | GRADED A+. What is the best agent to use against mycoplasma? - ANSWER-BM cyclin - a combination of two antibiotics (tiamulin and minocycline) that effecticely targets mycoplasma growth When harvesting peripheral blood cultures, asceptic technique no longer matters following incubation with: - ANSWER-Colcemid - mitotic spindle poison that halts cells at metaphase When scoring FISH for DiGeorge syndrome, a tech notices the TUPLE1 signal is present, but one of the control ARSA probe signals is missing in every cell. This result suggests __ ? - ANSWER-The patient has a deletion of the ARSA region CLIA 1988- (Clinical Laboratory Improvement Amendments) stipulates that equipment must be recalibrated __ ? - ANSWEREvery 6 months (Standard 493.1217) What type of stained chromosome would produce a better computer image? - ANSWER-Lightly stained chromosomes (best contrast and can be digitally edited easier) What is the nomenclature on a patient with down syndrome referred for a hematologic disorder where only trisomy 21 was found? - ANSWER-47,XY,+21c[20] For successful harvest, each new batch of hypotonic solution should be evaluated by: - ANSWERcomparing the new lot to a lot already in use Colagenase, pronase, and trypsin are: - ANSWER-Proteolytic enzymes - break down tissues into single-cell suspensions 24 hours after culture initiation, a single dish from an amniotic fluid turns cloudy. Which cultures should be disposed? - ANSWER-The single cloudy dish only What is used to reduce mycoplasma contamination? - ANSWERBM cycline CLIA '88 stipulates that equipment must be recalibrated ____ ? - ANSWER-After a major repair to ensure still operational How should caustic and corrosive chemicals be stored? - ANSWERBoth should be stored in a nonflammable cabinet CBG = c-bands achieved with barium with Giemsa stain CBG negative referrs to not having a centromere, which is crucial to being included in the modal number, so this extra fragment does not have a centromere and is not counted towards the total What is included when recording the modal number? - ANSWERMar - a marker chromosome is included because it has a centromere What is the BEST way to avoid producing ghost-like, pale chromosomes while staining? - ANSWERDecrease trypsin time In order to ensure successful harvest, each new batch of hypotonic solution should be evaluated ____. - ANSWER-By comparing new hypotonic solution to that already in use Which cell type would you want to use for long term serial cytogenetic studies? - ANSWERFibroblast cells What is not a necessary (must be added) ingredient which is added to modified medium? - ANSWER-Antibiotics What chemical is used for cryopreservation? - ANSWER-Dimethyl sulfoxide (DMSO) What factors would contribute to ALL cultures failing in a CO2 incubator? - ANSWER-Temperature CO2 level Humidity level What is the modal number for a diploid karyotype and an additional CBG negative marker chromosome? - ANSWER-46 You are analyzing a clinical case and discover a small extra marker with satellites. What staining technique would be most useful in determining the chromosomal origin of this marker? - ANSWER-NOR When using a fluorescein dye (yellow-green) labeled probe during the FISH procedure, which counterstain should be used? - ANSWER-Propidium iodide (red) A bone marrow sample collected in transport medium is leaking into the sealed plastic bag in which it was transported. The technologist should_______. - ANSWER-Clean up the tube while wearing gloves The morning after being set-up, a single dish of an amniotic fluid culture turns cloudy and appears contaminated. None of the other cultures set-up that day appears contaminated. What should be done first? - ANSWER-Harvest the culture as soon as possible