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Lecture notes Anatomy and physiology of Gall bladder (ANAT-101) Guyton and Hall Textbook of Medical Physiology

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Master the complex anatomy and physiology of the hepatobiliary system with these structured, exam-focused study notes. Developed by a medical student specializing in Anesthesia, these notes simplify difficult concepts into easy-to-digest sections perfect for USMLE Step 1, NCLEX, and final professional exams. These notes include comprehensive gross anatomy of gall bladder, the billary pathway, high yield mnemonics, microscopic anatomy and clinical correlations.

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Gall bladder + Mnemonics
Full details and well explained

Outline:
●​ What's gall bladder
●​ Anatomy and key parts
●​ Physiology of gall bladder
●​ What is bile
●​ Blood supply
●​ Nerves and hormonal control
●​ Common gall bladder diseases
●​ Clinical signs
●​ Why gall bladder is important
●​ Clinical scenario (with examples)




What is the Gall bladder?

The Gall bladder is a small, pear-shaped, hollow organ. It stores, concentrates, and releases
bile (produced by liver).
Located under the right lobe of the liver.
Does NOT produce bile!
●​ Length: ~7–10 cm
●​ Capacity: 30–50 mL
●​ Color: Greenish due to bile



Anatomy & Key Parts
Location:

, It is located in the Right Upper Quadrant (RUQ) of the abdomen under the right lobe of the
liver.
Parts of the gall bladder:
●​ Fundus (rounded bottom; projects beyond the liver margin)
●​ Body (main middle; lies in contact with the liver)
●​ Neck ( Narrow part; continues as the cystic duct).




Ducts:
A duct is a channel that transports fluids.
Cystic duct: Comes out of the gall bladder
Connects gall bladder to the duct system
Bile enters and leaves the gall bladder through this duct.
Common Bile Duct: sends bile to duodenum
Pancreatic duct: joins near ampulla
Mnemonics:
Ducts: C.C.P. – Cool Common Paths
Cystic, Common, Pancreatic.



Physiology of the Gall bladder

Bile Storage: Liver produces bile continuously; gallbladder stores 30–60 mL.
Bile Concentration: Removes water & electrolytes, making bile 5–10x stronger for fat
digestion.
Bile Release: Fatty food in duodenum triggers CCK release, causing gallbladder
contraction.
Flow of bile:
●​ When gall bladder is filling:
Liver → Common hepatic duct → Cystic duct → Gall bladder
●​ When gall bladder is emptying (after fatty food):
Gall bladder → Cystic duct → Common bile duct → Duodenum

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Uploaded on
February 6, 2026
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