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NR293: Anti-anginal, Heart Failure, and
Antidysrhythmic Drugs (Chapters 23-25)
Questions and Answers Latest Update
What are the functions of nitrates? Ans: Example: Nitroglycerin (large first-
pass effect)
Sublingual for acute
PO/topical for prevention
Dilates arteries and veins; decreases preload.
Dilates coronary arteries; increases O2 supply to heart.
What are the indications for nitrates? Ans: Stable, unstable, or vasospastic
angina.
What are the contraindications of nitrates? Ans: Hypotension
Slosed angle glaucoma
Severe head injury
Concurrent use of ED drugs (ie sildenafil)
What are the adverse effects of nitrates? Ans: Headaches: Improves with
continued use
Cardio: Reflex tachycardia; postural hypotension
© 2025 All rights reserved
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Topical forms: Contact dermatitis
Tolerance in ATC dosing or long-acting forms
Transdermal forms: Remove patch at bedtime for 8 hours, then apply a new
patch in the morning, chest and upper arm.
What is the client teaching for nitrates (sublingual route)? Ans: Never to
chew or swallow
Burning sensation; expected, still potent
Store in container, avoid exposure to light and moisture
Sit or lie down before taking; avoid syncope/dizziness
Take prn first sign of anginal pain
What is the client teaching for nitrates (topical route)? Ans: Rotate site of
application, remove old medicine.
Patch-free overnight to prevent tolerance.
What are the functions of beta 1 adrenergics? Ans: Example: Dobutamine
(only IV)
Increase cardiac output; positive inotrope
What are the indications for beta 1 adrenergics? Ans: Heart failure
Cardiac decompensation
What are the adverse effects of beta 1 adrenergics? Ans: Headache
Nervousness
© 2025 All rights reserved
NR293: Anti-anginal, Heart Failure, and
Antidysrhythmic Drugs (Chapters 23-25)
Questions and Answers Latest Update
What are the functions of nitrates? Ans: Example: Nitroglycerin (large first-
pass effect)
Sublingual for acute
PO/topical for prevention
Dilates arteries and veins; decreases preload.
Dilates coronary arteries; increases O2 supply to heart.
What are the indications for nitrates? Ans: Stable, unstable, or vasospastic
angina.
What are the contraindications of nitrates? Ans: Hypotension
Slosed angle glaucoma
Severe head injury
Concurrent use of ED drugs (ie sildenafil)
What are the adverse effects of nitrates? Ans: Headaches: Improves with
continued use
Cardio: Reflex tachycardia; postural hypotension
© 2025 All rights reserved
, 2 | Page
Topical forms: Contact dermatitis
Tolerance in ATC dosing or long-acting forms
Transdermal forms: Remove patch at bedtime for 8 hours, then apply a new
patch in the morning, chest and upper arm.
What is the client teaching for nitrates (sublingual route)? Ans: Never to
chew or swallow
Burning sensation; expected, still potent
Store in container, avoid exposure to light and moisture
Sit or lie down before taking; avoid syncope/dizziness
Take prn first sign of anginal pain
What is the client teaching for nitrates (topical route)? Ans: Rotate site of
application, remove old medicine.
Patch-free overnight to prevent tolerance.
What are the functions of beta 1 adrenergics? Ans: Example: Dobutamine
(only IV)
Increase cardiac output; positive inotrope
What are the indications for beta 1 adrenergics? Ans: Heart failure
Cardiac decompensation
What are the adverse effects of beta 1 adrenergics? Ans: Headache
Nervousness
© 2025 All rights reserved
