NURS 323 Pharm Quiz 1 Questions With
100% Correct Answers
\Q\.Place the following routes of medication administration in order of most bioavailable to
least bioavailable: IM/SQ, PO, IV - ANSWERS✔-Most: IV
IM/SQ
Least: PO
\Q\.Which drug needs special transport across a cell membrane in order to be effective?
a) Lipid soluble meds and ionized
b) Water soluble meds and non-ionized - ANSWERS✔-b) Water soluble meds and non-ionized
\Q\.Mr. Jones is taking drug A which is metabolized by the CYP3A4 enzyme in the liver. He loves
to drink grapefruit juice which is a known inhibitor of that enzyme. If this inhibits the enzyme,
will the patient have higher levels of the drug in the body or lower levels of the drug? -
ANSWERS✔-Higher levels of the drug
\Q\.Mrs. Smith is taking drug C which is metabolized by the CYP3A4 enzyme in the liver. She just
started on drug D which is a known inducer of that enzyme. If this induces the enzyme, will the
patient have higher levels of drug C in the body or lower levels of drug C in the body? -
ANSWERS✔-Lower levels of drug C
\Q\.Drug X has a narrow therapeutic range of 1-3. What does that mean for safety implications?
- ANSWERS✔-Less safe
, \Q\.Drug H has a half life of 2 days. When a patient starts taking this medication it will take
_____ to _____ days to reach plateau. - ANSWERS✔-8 to 10
\Q\.Providers may prescribe loading and maintenance doses of some drugs to achieve plateau
faster. The nurse knows the loading dose will be _____ and the maintenance dose will be _____.
(Lower or higher) - ANSWERS✔-Loading dose will be higher and the maintenance dose will be
lower.
\Q\.Drug Y mimics the action of endogenous hormone T filling the receptors which makes it
a(n):
a) Agonist
b) Antagonist - ANSWERS✔-a) Agonist
\Q\.If an antagonist is constantly blocking a receptor, does that make the receptor more or less
sensitive when it is eventually filled by the agonist? - ANSWERS✔-More sensitive
\Q\.A patient has been taking a brand-name drug, which is now being changed to generic. The
patient asks the nurse if he should pay out of his pocket to continue receiving the brand name
drug. Your response is:
a) Generic drugs have the same active ingredients as their brand name equivalent
b) Trade name drugs contain different active ingredients than generic drugs
c) Generic meds can be absorbed differently
d) Brand name drugs are worth the price difference because they work better - ANSWERS✔-a)
Generic drugs have the same active ingredients as their brand name equivalent
100% Correct Answers
\Q\.Place the following routes of medication administration in order of most bioavailable to
least bioavailable: IM/SQ, PO, IV - ANSWERS✔-Most: IV
IM/SQ
Least: PO
\Q\.Which drug needs special transport across a cell membrane in order to be effective?
a) Lipid soluble meds and ionized
b) Water soluble meds and non-ionized - ANSWERS✔-b) Water soluble meds and non-ionized
\Q\.Mr. Jones is taking drug A which is metabolized by the CYP3A4 enzyme in the liver. He loves
to drink grapefruit juice which is a known inhibitor of that enzyme. If this inhibits the enzyme,
will the patient have higher levels of the drug in the body or lower levels of the drug? -
ANSWERS✔-Higher levels of the drug
\Q\.Mrs. Smith is taking drug C which is metabolized by the CYP3A4 enzyme in the liver. She just
started on drug D which is a known inducer of that enzyme. If this induces the enzyme, will the
patient have higher levels of drug C in the body or lower levels of drug C in the body? -
ANSWERS✔-Lower levels of drug C
\Q\.Drug X has a narrow therapeutic range of 1-3. What does that mean for safety implications?
- ANSWERS✔-Less safe
, \Q\.Drug H has a half life of 2 days. When a patient starts taking this medication it will take
_____ to _____ days to reach plateau. - ANSWERS✔-8 to 10
\Q\.Providers may prescribe loading and maintenance doses of some drugs to achieve plateau
faster. The nurse knows the loading dose will be _____ and the maintenance dose will be _____.
(Lower or higher) - ANSWERS✔-Loading dose will be higher and the maintenance dose will be
lower.
\Q\.Drug Y mimics the action of endogenous hormone T filling the receptors which makes it
a(n):
a) Agonist
b) Antagonist - ANSWERS✔-a) Agonist
\Q\.If an antagonist is constantly blocking a receptor, does that make the receptor more or less
sensitive when it is eventually filled by the agonist? - ANSWERS✔-More sensitive
\Q\.A patient has been taking a brand-name drug, which is now being changed to generic. The
patient asks the nurse if he should pay out of his pocket to continue receiving the brand name
drug. Your response is:
a) Generic drugs have the same active ingredients as their brand name equivalent
b) Trade name drugs contain different active ingredients than generic drugs
c) Generic meds can be absorbed differently
d) Brand name drugs are worth the price difference because they work better - ANSWERS✔-a)
Generic drugs have the same active ingredients as their brand name equivalent
