Test bank for Tietz Fundamentals of Clinical Chemistry
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation
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Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones
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Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes
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,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
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Bank
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MULTIPLE CHOICE Qg
1. An individual working in a clinical chemistry laboratory is married to a sales
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representative who works for a company that sells chemistry laboratory supplies.
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When the laboratory manager requests a list of needed supplies, cost of supplies,
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and vendors, this individual onlyrecommends the spouse’s company as the vendor.
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This is considered to be a(n):
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a. accounting issue. Qg
b. possible conflict of interest. Qg Qg Qg
c. maintenance of confidentiality issue. Qg Qg Qg
d. problem with resource allocation. Qg Qg Qg
ANS: B Qg
Concern has been raised over the interrelationships between practitioners in the
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medical fieldand commercial suppliers of drugs, devices, equipment, etc., to the
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medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and
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manufacturers and providers of diagnostic equipment and supplies. These concerns
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led the National Institutes of Health (NIH) in 1995 to require official institutional
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review of financial disclosure by researchers and management of situations in which
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disclosure indicates potentialconflicts of interest.
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DIF: 1 REF: Qg Qg Qg Page 4-5 Qg OBJ: 6 | 7 Qg Qg Qg
2. A patient visits her physician stating that her prescribed painkiller is not working to
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reduce the pain following her recent surgery. A friend of the patient claims that
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the same painkiller“worked wonders” to reduce her pain after the same surgery.
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The physician states that the difference in the effect of the drug might be caused
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by
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pharmacogenetics.
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a. epidemiology
b. an inherited disease Qg Qg
c. a conflict of interest
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d. a genetic variation in drug-metabolizing enzymes
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ANS: D Qg
Pharmacogenetics is the study of the genetic variation of drug metabolism Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
betweenindividuals.
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DIF: 1 REF: Qg Qg Qg Page 3 Qg OBJ: 1 Qg
3. John works in a molecular diagnostics laboratory and receives a blood sample that
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has the name of a close friend printed on the bar-coded label. The genetic test
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that is ordered on thefriend’s sample would provide diagnostic information about
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a disorder that has a poor prognosis, and the test is usually performed by John.
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He asks a fellow employee to analyzethe sample for him and not divulge the
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results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. Qg Qg Qg Qg Qg Qg
b. a conflict of interest.
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and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
Qg Qg Qg Qg Qg Qg Qg Qg
Qg
Qg Qg
Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 3. Clinical Evaluation of Methods
Qg Qg Qg Qg Qg
Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
Qg Qg Qg Qg Qg Qg Qg
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 7. Quality Management
Qg Qg Qg
II. Analytical Techniques And Instrumentation
Qg Qg Qg Qg
Chapter 8. Principles of Basic Techniques and Laboratory Safety
Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 9. Optical Techniques
Qg Qg Qg
Chapter 10. Electrochemistry and Chemical Sensors
Qg Qg Qg Qg Qg
Chapter 11. Electrophoresis
Qg Qg
Chapter 12. Chromatography
Qg Qg
Chapter 13. Mass Spectrometry
Qg Qg Qg
Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
Qg Qg Qg
Chapter 16 Automation
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Chapter 17. Point-of-Care Instrumentation
Qg Qg Qg
III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
Qg Qg Qg Qg Qg
Chapter 25. Hormones
Qg Qg
Chapter 26. Catecholamines and Serotonin
Qg Q g Qg Qg
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
Qg Q g Qg Qg Qg Qg
Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
Qg Q g Qg
IV. Pathophysiology
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Chapter 33. Diabetes
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,Chapter 34. Cardiovascular Disease
Qg Q g Qg
Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
Qg Q g Qg Qg Qg Qg Qg Qg Qg Qg
Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
Qg Qg Qg Qg Qg Qg Qg Qg Qg
Bank
gQ
MULTIPLE CHOICE Qg
1. An individual working in a clinical chemistry laboratory is married to a sales
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
representative who works for a company that sells chemistry laboratory supplies.
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
When the laboratory manager requests a list of needed supplies, cost of supplies,
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
and vendors, this individual onlyrecommends the spouse’s company as the vendor.
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This is considered to be a(n):
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a. accounting issue. Qg
b. possible conflict of interest. Qg Qg Qg
c. maintenance of confidentiality issue. Qg Qg Qg
d. problem with resource allocation. Qg Qg Qg
ANS: B Qg
Concern has been raised over the interrelationships between practitioners in the
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
medical fieldand commercial suppliers of drugs, devices, equipment, etc., to the
Qg Qg gQ Qg Qg Qg Qg Qg Qg Qg Qg Qg
medical profession.
Qg Qg
Similarly, relationships have been scrutinized between clinical laboratorians and
Qg Qg Qg Qg Qg Qg Qg Qg
manufacturers and providers of diagnostic equipment and supplies. These concerns
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
led the National Institutes of Health (NIH) in 1995 to require official institutional
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
review of financial disclosure by researchers and management of situations in which
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
disclosure indicates potentialconflicts of interest.
Qg Qg Qg gQ Qg Qg
DIF: 1 REF: Qg Qg Qg Page 4-5 Qg OBJ: 6 | 7 Qg Qg Qg
2. A patient visits her physician stating that her prescribed painkiller is not working to
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
reduce the pain following her recent surgery. A friend of the patient claims that
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
the same painkiller“worked wonders” to reduce her pain after the same surgery.
Qg Qg Qg gQ Qg Qg Qg Qg Qg Qg Qg Qg Qg
The physician states that the difference in the effect of the drug might be caused
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
by
Qg , which is studied in Qg Qg Qg Qg
pharmacogenetics.
Qg
a. epidemiology
b. an inherited disease Qg Qg
c. a conflict of interest
Qg Qg Qg
d. a genetic variation in drug-metabolizing enzymes
Qg Qg Qg Qg Qg
ANS: D Qg
Pharmacogenetics is the study of the genetic variation of drug metabolism Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
betweenindividuals.
Qg gQ
DIF: 1 REF: Qg Qg Qg Page 3 Qg OBJ: 1 Qg
3. John works in a molecular diagnostics laboratory and receives a blood sample that
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
has the name of a close friend printed on the bar-coded label. The genetic test
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
that is ordered on thefriend’s sample would provide diagnostic information about
Qg Qg Qg Qg Qg gQ Qg Qg Qg Qg Qg Qg
a disorder that has a poor prognosis, and the test is usually performed by John.
Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg Qg
He asks a fellow employee to analyzethe sample for him and not divulge the
Qg Qg Qg Qg Qg Qg Qg gQ Qg Qg Qg Qg Qg Qg Qg
results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. Qg Qg Qg Qg Qg Qg
b. a conflict of interest.
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