The eyes begin to form as a population of cells in the:
A) Mesencephalon
B) Midbrain
C) Rhombencephalon
D) Prosencephalon
E) Floorplate - Answer Answer: D
The Lens Placode is induced by the contact between the neural ectoderm of the ______ and the
________
A) Optic Stalk/Optic Cup
B) Optic Vesicle/Surface Ectoderm
C) Forebrain/Optic Stalk
D) Optic Groove/Surface Ectoderm
E) Optic Stalk/Surface Ectoderm - Answer Answer: B
Corneal development is induced by the ________ acting on the overlying surface ectoderm
A) Lens Vesicle
B) Optic Vesicle
C) Lens Placode
D) Optic Cup
E) Optic Stalk - Answer Answer: A
Cyclopia is the result of which of the following?
A) Absence of Pax6 and underdevelopment of eyes
B) Absence of SHH causing optic fields to converge
C) Downregulation of Pax6 in the ventral midline of the diencephalon
D) Overexpression of SHH in the forebrain causing optic fields to diverge
E) None of the above - Answer Answer: B
SHH is needed to cause the optic fields to separate in two. No SHH = one optic field = cyclopia =
cyclops
Coloboma is due to which of the following?
A) Abnormal development of lens vesicle