Biochemistry ACS Final Exam Questions
With Correct Answers
What is the Henderson-Hasselbach ? - CORRECT ANSWER✔✔-pH = pka + log
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([A]/[Ha])
High Ka, low pka indicates what? - CORRECT ANSWER✔✔-Strong acid
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What is the relation between pH and [H+]? - CORRECT ANSWER✔✔-pH = -log[H+]
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What is the realtionship between pka and Ka? - CORRECT ANSWER✔✔-pka = -
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logKa
What makes a good buffer? - CORRECT ANSWER✔✔-A weak acid mixed with its
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conjugate base in a 50/50 ratio
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What destroys tryptophan? - CORRECT ANSWER✔✔-Acids and bases
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What is the isoelectric point? - CORRECT ANSWER✔✔-The pH in which a
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particular molecule carries no net charge (pI)
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Side chain pka of aspartic acid? - CORRECT ANSWER✔✔-~ 3.86
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, Side chain pka of arginine? - CORRECT ANSWER✔✔-~ 12.48
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Side chain pka of cysteine? - CORRECT ANSWER✔✔-~8.0
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Side chain pka of glutamic acid? - CORRECT ANSWER✔✔-~4.07
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Side chain pka of histidine? - CORRECT ANSWER✔✔-~6.1
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Side chain pka of lysine? - CORRECT ANSWER✔✔-~10.53
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Side chain pka of tyrosine? - CORRECT ANSWER✔✔-~10.00
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Inductive effect on pka? - CORRECT ANSWER✔✔-Electronegative atoms pull
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electrons away from another group, and makes that particular groups more
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positive. Generally lowers pka
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Electrostatic effect on pka? - CORRECT ANSWER✔✔-Nearby positive charge
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makes a proton want to leave more, generally lowers pka.
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Distance effect on pka? - CORRECT ANSWER✔✔-Generally lowers the influence of
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inductive and electrostatic effects
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How are amino acids read? - CORRECT ANSWER✔✔-N terminus to C terminus
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With Correct Answers
What is the Henderson-Hasselbach ? - CORRECT ANSWER✔✔-pH = pka + log
| | | | | | | | | | | |
([A]/[Ha])
High Ka, low pka indicates what? - CORRECT ANSWER✔✔-Strong acid
| | | | | | | | |
What is the relation between pH and [H+]? - CORRECT ANSWER✔✔-pH = -log[H+]
| | | | | | | | | | | |
What is the realtionship between pka and Ka? - CORRECT ANSWER✔✔-pka = -
| | | | | | | | | | | |
logKa
What makes a good buffer? - CORRECT ANSWER✔✔-A weak acid mixed with its
| | | | | | | | | | | | |
conjugate base in a 50/50 ratio
| | | | |
What destroys tryptophan? - CORRECT ANSWER✔✔-Acids and bases
| | | | | | |
What is the isoelectric point? - CORRECT ANSWER✔✔-The pH in which a
| | | | | | | | | | | |
particular molecule carries no net charge (pI)
| | | | | |
Side chain pka of aspartic acid? - CORRECT ANSWER✔✔-~ 3.86
| | | | | | | | |
, Side chain pka of arginine? - CORRECT ANSWER✔✔-~ 12.48
| | | | | | | |
Side chain pka of cysteine? - CORRECT ANSWER✔✔-~8.0
| | | | | | |
Side chain pka of glutamic acid? - CORRECT ANSWER✔✔-~4.07
| | | | | | | |
Side chain pka of histidine? - CORRECT ANSWER✔✔-~6.1
| | | | | | |
Side chain pka of lysine? - CORRECT ANSWER✔✔-~10.53
| | | | | | |
Side chain pka of tyrosine? - CORRECT ANSWER✔✔-~10.00
| | | | | | |
Inductive effect on pka? - CORRECT ANSWER✔✔-Electronegative atoms pull
| | | | | | | | |
electrons away from another group, and makes that particular groups more
| | | | | | | | | | |
positive. Generally lowers pka
| | |
Electrostatic effect on pka? - CORRECT ANSWER✔✔-Nearby positive charge
| | | | | | | | |
makes a proton want to leave more, generally lowers pka.
| | | | | | | | |
Distance effect on pka? - CORRECT ANSWER✔✔-Generally lowers the influence of
| | | | | | | | | |
inductive and electrostatic effects
| | | |
How are amino acids read? - CORRECT ANSWER✔✔-N terminus to C terminus
| | | | | | | | | | |