Quiz_________________?
__________ increase GABA's inhibitory activity, leading to the decreased output of
excitatory neurotransmitters resulting in the adverse effects related to their use -
Answer✅
Benzodiazepines (BZOs)
Quiz_________________?
________,_________,_________,________ are all key modulators of the hypothetical
fear and worry circuits -
Answer✅
Serotonin, norepinephrine, alpha-2 delta ligands and GABA
Quiz_________________?
__% of the population will develop an anxiety disorder -
Answer✅
30%
Quiz_________________?
1
, 2 dones and a rone -
Answer✅
-more potently to the 5HT 2A receptor than to D2 or bine equally between the 2
receptors.
-less sedating and cause less weight gain, but have a higher risk for hyperprolactinemia and
EPS
Quiz_________________?
2 pips and a rip -
Answer✅
-pips: bind more potently to D2 receptors than to 5HT-2A, have low risk of metabolic side
effects and weight gain, but they have a potential for EPS.
-rips binds equally to both D2 and 5HT-2A receptors, have low risk for metabolic disorders
Quiz_________________?
5HT -
Answer✅
Serotonin
-help regulate mood
-makes relaxed, comfortable, decreases stress, regulate sleep, arousal, libido, aggression,
pain perception
Quiz_________________?
Abnormal Involuntary Movement Scale (AIMS) -
Answer✅
tool used to monitor involuntary movements and tardive dyskinesia in clients who take
antipsychotic medication
2
, -best practice/recommendation to document the AIMS at minimum every 6 months for
patients taking an antipsychotic agent/dopamine blocker
Quiz_________________?
abrupt cessation of benzodiazepines -
Answer✅
can lead to severe withdrawal symptoms
-seizures and death
Quiz_________________?
Ach -
Answer✅
acetylcholine
-in CNS: affects arousal, motivation, attention, learning, REM sleep, impacts sleep, pain
perception, memory
-in PNS: makes you sweat and salivate
-link between brain and muscles
-not enough: Alzheimer's, Parkinson's, Schizophrenia
-too much: Depression
-Role in addiction
-Receptors: nicotinic & muscarinic
Quiz_________________?
adding 5HT2A antagonism: -
Answer✅
improve side effects of D2 blockade and enhance the antipsychotic efficacy of D2 blockade
3
, Quiz_________________?
Additional adverse effects of excessive D2 receptor blockade (D2 antagonist actions)
include: -
Answer✅
-cardiac concerns: QT prolongation, torsades de pointes, and sudden cardiac death
-blood dyscrasias (neutropenia, leukopenia, and agranulocytosis)
-esophageal dysmotility, aspiration
-increased fall risk
Quiz_________________?
Adherence -
Answer✅
Persistence
-taking med over intended time period
Compliance
-taking med as prescribed
Quiz_________________?
Affect of fear -
Answer✅
regulated by reciprocal connections between the amygdala and the anterior cingulate cortex
(ACC) and the amygdala and the orbitofrontal cortex (OFC)
Quiz_________________?
4