NUR 370 Exam 1
Role of the nurse in clinical pharmacology - 🧠 ANSWER ✔✔Adminstration,
assessment of effects, intervention, client education, prevention of
medication errors
Preclinical trials - 🧠 ANSWER ✔✔No human participants, cells or animals,
to see what the drug will do and adverse effects
Phase 1 Drug Trials - 🧠 ANSWER ✔✔Human participants, sick or not, tests
safety, dosage, and effects
Phase 2 drug trials - 🧠 ANSWER ✔✔Humans with the illness, decide if
effects are worth it
Phase 3 drug trials - 🧠 ANSWER ✔✔Increased sample size to examine
larger scale effects
,Phase 4 drug trials - 🧠 ANSWER ✔✔Continual evaluation as it's on the
market
Trade name - 🧠 ANSWER ✔✔Capitalized, name given by the company
who first markets the drug
Generic name - 🧠 ANSWER ✔✔Lowercase, drug name at the start of the
approval process, may differ in inactive ingredients
Pharmacodynamics - 🧠 ANSWER ✔✔How the drug impacts the body
Drugs work by - 🧠 ANSWER ✔✔1. Replacing/substituting a missing
chemical
2. Increasing/stimulating cellular activity
3. Depressing/slowing cellular activity
Receptor sites drugs - 🧠 ANSWER ✔✔The sensitivity of receptors and
amount/duration of the drug impacts the effect → impacts cell
Pharmacokinetics - 🧠 ANSWER ✔✔How the body impacts the drug
(absorption, distribution, metabolism, excretion)
Onset of drug - 🧠 ANSWER ✔✔How quickly it starts to work
, Peak drug level - 🧠 ANSWER ✔✔When the drug is at it's highest
concentration in the blood
Drug absorption - 🧠 ANSWER ✔✔Can be through gi, skin, mucous
membrane, veins, lungs, muscle, subcutaneous tissue → may be impacted
based on route
Drug distribution - 🧠 ANSWER ✔✔1. Tissue perfusion 2. Protein binding,
loosely or tightly bound 3. Cell membrane permeability
Drug metabolism - 🧠 ANSWER ✔✔Liver processes drugs to be less active
First pass effect - 🧠 ANSWER ✔✔Oral drugs go directly to the liver after
absorption, they may become largely inactivated by liver enzymes before
they can enter the general circulation
Drug excretion - 🧠 ANSWER ✔✔Kidney takes blood and creates urea,
remaining drug is peed out
Pregnancy + drugs - 🧠 ANSWER ✔✔Highly regulated, teratogenic effect
levels
Herbal therapies + supplements - 🧠 ANSWER ✔✔Not FDA regulated and
can cause interactions, not all ingredients are known
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
Role of the nurse in clinical pharmacology - 🧠 ANSWER ✔✔Adminstration,
assessment of effects, intervention, client education, prevention of
medication errors
Preclinical trials - 🧠 ANSWER ✔✔No human participants, cells or animals,
to see what the drug will do and adverse effects
Phase 1 Drug Trials - 🧠 ANSWER ✔✔Human participants, sick or not, tests
safety, dosage, and effects
Phase 2 drug trials - 🧠 ANSWER ✔✔Humans with the illness, decide if
effects are worth it
Phase 3 drug trials - 🧠 ANSWER ✔✔Increased sample size to examine
larger scale effects
,Phase 4 drug trials - 🧠 ANSWER ✔✔Continual evaluation as it's on the
market
Trade name - 🧠 ANSWER ✔✔Capitalized, name given by the company
who first markets the drug
Generic name - 🧠 ANSWER ✔✔Lowercase, drug name at the start of the
approval process, may differ in inactive ingredients
Pharmacodynamics - 🧠 ANSWER ✔✔How the drug impacts the body
Drugs work by - 🧠 ANSWER ✔✔1. Replacing/substituting a missing
chemical
2. Increasing/stimulating cellular activity
3. Depressing/slowing cellular activity
Receptor sites drugs - 🧠 ANSWER ✔✔The sensitivity of receptors and
amount/duration of the drug impacts the effect → impacts cell
Pharmacokinetics - 🧠 ANSWER ✔✔How the body impacts the drug
(absorption, distribution, metabolism, excretion)
Onset of drug - 🧠 ANSWER ✔✔How quickly it starts to work
, Peak drug level - 🧠 ANSWER ✔✔When the drug is at it's highest
concentration in the blood
Drug absorption - 🧠 ANSWER ✔✔Can be through gi, skin, mucous
membrane, veins, lungs, muscle, subcutaneous tissue → may be impacted
based on route
Drug distribution - 🧠 ANSWER ✔✔1. Tissue perfusion 2. Protein binding,
loosely or tightly bound 3. Cell membrane permeability
Drug metabolism - 🧠 ANSWER ✔✔Liver processes drugs to be less active
First pass effect - 🧠 ANSWER ✔✔Oral drugs go directly to the liver after
absorption, they may become largely inactivated by liver enzymes before
they can enter the general circulation
Drug excretion - 🧠 ANSWER ✔✔Kidney takes blood and creates urea,
remaining drug is peed out
Pregnancy + drugs - 🧠 ANSWER ✔✔Highly regulated, teratogenic effect
levels
Herbal therapies + supplements - 🧠 ANSWER ✔✔Not FDA regulated and
can cause interactions, not all ingredients are known
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED
