2026 COMPREHENSIVE ATI
PHARMACOLOGY NURSING
PROTECTED EXAM QUESTIONS WITH
ANSWERS ALREADY GRADED
1. A nurse is providing teaching to a group of new parents about medications. The nurse
should include that aspirin is contraindicated for children who have a viral infection due
to the risk of developing which of the following adverse effects?
a. Reye's syndrome
b. Visual disturbances
c. Diabetes mellitus
d. Wilm's tumor
ANS: A
2. A nurse is providing teaching to a client who has chronic kidney failure with an AV
fistula for hemodialysis and new prescription for epoetin alfa. Which of the following
therapeutic effects of epoetin alfa should the nurse include in the teaching?
a. Reduces blood pressure
b. Inhibits clotting of fistula
c. Promotes RBC production
d. Stimulates growth of neutrophils
ANS: C
3. A nurse is caring for a client who has peptic ulcer disease and reports a headache. Which
of the following medications should the nurse plan to administer?
a. Ibuprofen (NSAIDS)
b. Naproxen (NSAIDS)
c. Aspirin (NSAIDS)
d. Acetaminophen (anlagesics)
ANS: D
4. A nurse is caring for a client who has prescription for clopidogrel. The nurse should
monitor the client for which of the following adverse effects?
a. Insomnia
b. Hypotension
c. Bleeding
d. Constipation
ANS: C
5. A nurse is teaching a newly licensed nurse about contraindications to ceftriaxone. The
nurse should include a severe allergy to which of the following medications as
1
,contraindication to ceftriaxone?
a. Gentamicin
b. Clindamycin
c. Piperacillin
d. Sulfamethoxazole-trimethroprim
ANS: C
2
, ANS: D
6. A nurse is reviewing laboratory values for a client who reports fatigue and cold
intolerance. The client has an increased thyroid stimulating hormone (TSH) level and a
decreased total T3 and T4 level. The nurse should anticipate a prescription for which of
the following medications?
a. Methimazole
b. Somatropin
c. Levothyroxine
d. Propylthiouracil
ANS: C
7. A nurse is providing teaching to a client who has a new prescription for
hydrochlorothiazide 50mg po daily to treat hypertension. Which of the following
instructions should the nurse include in the teaching?
a. Take the hydrochlorothiazide as needed for edema
b. Check your weight once each week
c. Take the hydrochlorothiazide on an empty stomach
d. Take the hydrochlorothiazide in the morning.
ANS: D
8. A nurse is caring for a client who is at 28 weeks of gestation and is experiencing preterm
labor. Which of the following medications should the nurse plan to administer?
a. Oxytocin
b. Nifedipine
c. Dinoprostone
d. Misoprostol
ANS: B
9. A nurse is providing teaching to a client who has cirrhosis and new prescription for
lactulose. The nurse should instruct the client that lactulose has which of the following
therapeutic effects?
a. Increases blood pressure
b. Prevents esophageal bleeding
c. Decreases heart rate
d. Reduce ammonia levels
ANS: D
10. A nurse is caring for an older adult client who has a new prescription for amitriptyline to
treat depression. Which of the following diagnostic tests should the nurse plan to perform
prior to starting the client on this medication?
a. Hearing examination
3
, b. Glucose tolerance test
4
PHARMACOLOGY NURSING
PROTECTED EXAM QUESTIONS WITH
ANSWERS ALREADY GRADED
1. A nurse is providing teaching to a group of new parents about medications. The nurse
should include that aspirin is contraindicated for children who have a viral infection due
to the risk of developing which of the following adverse effects?
a. Reye's syndrome
b. Visual disturbances
c. Diabetes mellitus
d. Wilm's tumor
ANS: A
2. A nurse is providing teaching to a client who has chronic kidney failure with an AV
fistula for hemodialysis and new prescription for epoetin alfa. Which of the following
therapeutic effects of epoetin alfa should the nurse include in the teaching?
a. Reduces blood pressure
b. Inhibits clotting of fistula
c. Promotes RBC production
d. Stimulates growth of neutrophils
ANS: C
3. A nurse is caring for a client who has peptic ulcer disease and reports a headache. Which
of the following medications should the nurse plan to administer?
a. Ibuprofen (NSAIDS)
b. Naproxen (NSAIDS)
c. Aspirin (NSAIDS)
d. Acetaminophen (anlagesics)
ANS: D
4. A nurse is caring for a client who has prescription for clopidogrel. The nurse should
monitor the client for which of the following adverse effects?
a. Insomnia
b. Hypotension
c. Bleeding
d. Constipation
ANS: C
5. A nurse is teaching a newly licensed nurse about contraindications to ceftriaxone. The
nurse should include a severe allergy to which of the following medications as
1
,contraindication to ceftriaxone?
a. Gentamicin
b. Clindamycin
c. Piperacillin
d. Sulfamethoxazole-trimethroprim
ANS: C
2
, ANS: D
6. A nurse is reviewing laboratory values for a client who reports fatigue and cold
intolerance. The client has an increased thyroid stimulating hormone (TSH) level and a
decreased total T3 and T4 level. The nurse should anticipate a prescription for which of
the following medications?
a. Methimazole
b. Somatropin
c. Levothyroxine
d. Propylthiouracil
ANS: C
7. A nurse is providing teaching to a client who has a new prescription for
hydrochlorothiazide 50mg po daily to treat hypertension. Which of the following
instructions should the nurse include in the teaching?
a. Take the hydrochlorothiazide as needed for edema
b. Check your weight once each week
c. Take the hydrochlorothiazide on an empty stomach
d. Take the hydrochlorothiazide in the morning.
ANS: D
8. A nurse is caring for a client who is at 28 weeks of gestation and is experiencing preterm
labor. Which of the following medications should the nurse plan to administer?
a. Oxytocin
b. Nifedipine
c. Dinoprostone
d. Misoprostol
ANS: B
9. A nurse is providing teaching to a client who has cirrhosis and new prescription for
lactulose. The nurse should instruct the client that lactulose has which of the following
therapeutic effects?
a. Increases blood pressure
b. Prevents esophageal bleeding
c. Decreases heart rate
d. Reduce ammonia levels
ANS: D
10. A nurse is caring for an older adult client who has a new prescription for amitriptyline to
treat depression. Which of the following diagnostic tests should the nurse plan to perform
prior to starting the client on this medication?
a. Hearing examination
3
, b. Glucose tolerance test
4
