Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
Which principle most directly supports patient-centered care
in modern clinical practice?
A. Maximizing diagnostic testing
B. Applying population averages to all patients
C. Integrating patient values with best evidence
D. Prioritizing physician expertise over patient input
Correct Answer: C
Rationale: High-quality care integrates scientific evidence with
patient preferences and values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1
,2. Promoting Good Health
Which nursing intervention best reflects primary prevention?
A. Blood glucose monitoring in diabetes
B. Smoking cessation counseling
C. Rehabilitation after stroke
D. Palliative pain management
Correct Answer: B
Rationale: Primary prevention aims to prevent disease onset by
addressing risk factors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 2
3. Vaccine Opposition and Hesitancy
What is the MOST effective nursing approach to vaccine
hesitancy?
A. Providing extensive technical data
B. Using authoritative directives
C. Listening empathetically and addressing concerns
D. Avoiding the topic unless asked
Correct Answer: C
Rationale: Trust-building and respectful dialogue improve
vaccine acceptance.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 3
,4. Decision-Making in Clinical Medicine
Shared decision-making is MOST appropriate when:
A. Evidence strongly favors one option
B. Multiple reasonable options exist
C. The patient lacks decisional capacity
D. Time-sensitive emergencies occur
Correct Answer: B
Rationale: Shared decision-making applies when benefits and
risks vary by patient values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 4
5. Precision Medicine and Clinical Care
Precision medicine primarily seeks to:
A. Replace clinical judgment
B. Standardize treatment for all patients
C. Tailor care using individual variability
D. Eliminate environmental risk assessment
Correct Answer: C
Rationale: Precision medicine integrates genetic,
environmental, and lifestyle factors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 5
, 6. Screening and Prevention of Disease
Which factor is MOST critical when evaluating a screening
test?
A. Test cost alone
B. Disease prevalence and test accuracy
C. Patient age only
D. Availability of treatment
Correct Answer: B
Rationale: Effective screening depends on disease prevalence
and sensitivity/specificity.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 6
7. The Safety and Quality of Health Care
Which nursing action best reduces medical errors?
A. Working independently
B. Minimizing documentation
C. Using standardized checklists
D. Relying on memory
Correct Answer: C
Rationale: System-based tools like checklists improve safety and
consistency.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 7
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
Which principle most directly supports patient-centered care
in modern clinical practice?
A. Maximizing diagnostic testing
B. Applying population averages to all patients
C. Integrating patient values with best evidence
D. Prioritizing physician expertise over patient input
Correct Answer: C
Rationale: High-quality care integrates scientific evidence with
patient preferences and values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1
,2. Promoting Good Health
Which nursing intervention best reflects primary prevention?
A. Blood glucose monitoring in diabetes
B. Smoking cessation counseling
C. Rehabilitation after stroke
D. Palliative pain management
Correct Answer: B
Rationale: Primary prevention aims to prevent disease onset by
addressing risk factors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 2
3. Vaccine Opposition and Hesitancy
What is the MOST effective nursing approach to vaccine
hesitancy?
A. Providing extensive technical data
B. Using authoritative directives
C. Listening empathetically and addressing concerns
D. Avoiding the topic unless asked
Correct Answer: C
Rationale: Trust-building and respectful dialogue improve
vaccine acceptance.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 3
,4. Decision-Making in Clinical Medicine
Shared decision-making is MOST appropriate when:
A. Evidence strongly favors one option
B. Multiple reasonable options exist
C. The patient lacks decisional capacity
D. Time-sensitive emergencies occur
Correct Answer: B
Rationale: Shared decision-making applies when benefits and
risks vary by patient values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 4
5. Precision Medicine and Clinical Care
Precision medicine primarily seeks to:
A. Replace clinical judgment
B. Standardize treatment for all patients
C. Tailor care using individual variability
D. Eliminate environmental risk assessment
Correct Answer: C
Rationale: Precision medicine integrates genetic,
environmental, and lifestyle factors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 5
, 6. Screening and Prevention of Disease
Which factor is MOST critical when evaluating a screening
test?
A. Test cost alone
B. Disease prevalence and test accuracy
C. Patient age only
D. Availability of treatment
Correct Answer: B
Rationale: Effective screening depends on disease prevalence
and sensitivity/specificity.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 6
7. The Safety and Quality of Health Care
Which nursing action best reduces medical errors?
A. Working independently
B. Minimizing documentation
C. Using standardized checklists
D. Relying on memory
Correct Answer: C
Rationale: System-based tools like checklists improve safety and
consistency.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 7
