Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1.
Which principle best defines the practice of medicine as
described in Harrison’s?
A. Application of standardized protocols
B. Integration of scientific evidence with patient values
C. Reliance on diagnostic technology
D. Population-based risk stratification
Correct Answer: B
Rationale: Harrison’s emphasizes medicine as the integration of
biomedical science, clinical expertise, and individual patient
values rather than rigid protocol adherence.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 1: The Practice of Medicine
2.
A nurse identifies that promoting good health primarily focuses
on which strategy?
A. Early disease detection
B. Reducing symptom severity
C. Enhancing protective behaviors
D. Managing chronic illness
Correct Answer: C
Rationale: Health promotion prioritizes strengthening
protective factors such as lifestyle behaviors and environmental
supports rather than disease treatment.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 2: Promoting Good Health
3.
Which factor is most strongly associated with vaccine
hesitancy?
A. Lack of vaccine availability
B. Distrust in medical institutions
,C. Cost of immunizations
D. Complexity of vaccine schedules
Correct Answer: B
Rationale: Harrison’s identifies mistrust in health systems and
authorities as a central driver of vaccine opposition and
hesitancy.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 3: Vaccine Opposition and Hesitancy
4.
Shared decision-making in clinical medicine requires the
clinician to:
A. Recommend the lowest-cost option
B. Present options aligned with patient goals
C. Defer decisions entirely to the patient
D. Prioritize guideline-directed therapy
Correct Answer: B
Rationale: Effective decision-making integrates evidence with
patient preferences and values through bidirectional
communication.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 4: Decision-Making in Clinical Medicine
, 5.
Precision medicine primarily differs from traditional care by
emphasizing:
A. Population-level screening
B. Symptom-based diagnosis
C. Individual biological variability
D. Cost-effectiveness
Correct Answer: C
Rationale: Precision medicine tailors prevention and treatment
based on genetic, environmental, and lifestyle differences
among individuals.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 5: Precision Medicine and Clinical Care
6.
Which screening principle is essential to prevent patient harm?
A. Screening should detect rare diseases
B. Early detection must improve outcomes
C. Screening should be inexpensive
D. All diseases should be screened
Correct Answer: B
Rationale: Harrison’s stresses that screening is justified only
when early detection improves morbidity or mortality.
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1.
Which principle best defines the practice of medicine as
described in Harrison’s?
A. Application of standardized protocols
B. Integration of scientific evidence with patient values
C. Reliance on diagnostic technology
D. Population-based risk stratification
Correct Answer: B
Rationale: Harrison’s emphasizes medicine as the integration of
biomedical science, clinical expertise, and individual patient
values rather than rigid protocol adherence.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 1: The Practice of Medicine
2.
A nurse identifies that promoting good health primarily focuses
on which strategy?
A. Early disease detection
B. Reducing symptom severity
C. Enhancing protective behaviors
D. Managing chronic illness
Correct Answer: C
Rationale: Health promotion prioritizes strengthening
protective factors such as lifestyle behaviors and environmental
supports rather than disease treatment.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 2: Promoting Good Health
3.
Which factor is most strongly associated with vaccine
hesitancy?
A. Lack of vaccine availability
B. Distrust in medical institutions
,C. Cost of immunizations
D. Complexity of vaccine schedules
Correct Answer: B
Rationale: Harrison’s identifies mistrust in health systems and
authorities as a central driver of vaccine opposition and
hesitancy.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 3: Vaccine Opposition and Hesitancy
4.
Shared decision-making in clinical medicine requires the
clinician to:
A. Recommend the lowest-cost option
B. Present options aligned with patient goals
C. Defer decisions entirely to the patient
D. Prioritize guideline-directed therapy
Correct Answer: B
Rationale: Effective decision-making integrates evidence with
patient preferences and values through bidirectional
communication.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 4: Decision-Making in Clinical Medicine
, 5.
Precision medicine primarily differs from traditional care by
emphasizing:
A. Population-level screening
B. Symptom-based diagnosis
C. Individual biological variability
D. Cost-effectiveness
Correct Answer: C
Rationale: Precision medicine tailors prevention and treatment
based on genetic, environmental, and lifestyle differences
among individuals.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 5: Precision Medicine and Clinical Care
6.
Which screening principle is essential to prevent patient harm?
A. Screening should detect rare diseases
B. Early detection must improve outcomes
C. Screening should be inexpensive
D. All diseases should be screened
Correct Answer: B
Rationale: Harrison’s stresses that screening is justified only
when early detection improves morbidity or mortality.
