Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
Which principle best defines evidence-based clinical practice
as described in Harrison’s?
A. Reliance on expert opinion alone
B. Use of randomized trials only
C. Integration of best evidence, clinical expertise, and patient
values
D. Adherence to institutional protocols exclusively
Correct Answer: C
Rationale: Evidence-based medicine integrates scientific
evidence with clinician expertise and patient preferences to
guide care.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 – The Practice of Medicine
2. The Practice of Medicine
Which nursing action most supports patient-centered care?
A. Limiting patient involvement in decisions
B. Applying standardized care without modification
C. Incorporating patient goals into the care plan
D. Prioritizing cost reduction over outcomes
Correct Answer: C
Rationale: Patient-centered care requires aligning treatment
plans with individual patient values and goals.
Citation: Harrison’s, 22nd ed., Ch. 1
3. Promoting Good Health
Which factor is most strongly associated with reduced
morbidity across populations?
A. Advanced diagnostic imaging
B. Lifestyle modification
C. Increased specialty referrals
D. Expanded pharmacotherapy
Correct Answer: B
Rationale: Health promotion emphasizes lifestyle factors (diet,
exercise, smoking cessation) as major determinants of long-
,term outcomes.
Citation: Harrison’s, 22nd ed., Ch. 2 – Promoting Good Health
4. Promoting Good Health
Which nursing intervention best reflects primary prevention?
A. Blood glucose monitoring
B. Smoking cessation counseling
C. Cardiac rehabilitation
D. Pain management
Correct Answer: B
Rationale: Primary prevention aims to prevent disease before it
occurs through risk reduction.
Citation: Harrison’s, 22nd ed., Ch. 2
5. Vaccine Opposition and Hesitancy
Which factor most commonly contributes to vaccine
hesitancy?
A. Lack of vaccine availability
B. Concerns about safety and trust
C. Provider recommendation
D. Genetic variability
Correct Answer: B
Rationale: Harrison’s identifies safety concerns, misinformation,
and distrust as major drivers of hesitancy.
, Citation: Harrison’s, 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
6. Vaccine Opposition and Hesitancy
What is the nurse’s most effective role in addressing vaccine
hesitancy?
A. Avoiding discussion
B. Providing clear, empathetic education
C. Enforcing vaccination
D. Referring all questions to physicians
Correct Answer: B
Rationale: Trust-building and respectful communication are
essential to improving vaccine acceptance.
Citation: Harrison’s, 22nd ed., Ch. 3
7. Decision-Making in Clinical Medicine
Which concept is central to shared decision-making?
A. Clinician authority
B. Patient autonomy with informed consent
C. Algorithm-based care
D. Cost minimization
Correct Answer: B
Rationale: Shared decision-making balances medical evidence
with patient values and informed choice.
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
1. The Practice of Medicine
Which principle best defines evidence-based clinical practice
as described in Harrison’s?
A. Reliance on expert opinion alone
B. Use of randomized trials only
C. Integration of best evidence, clinical expertise, and patient
values
D. Adherence to institutional protocols exclusively
Correct Answer: C
Rationale: Evidence-based medicine integrates scientific
evidence with clinician expertise and patient preferences to
guide care.
,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 – The Practice of Medicine
2. The Practice of Medicine
Which nursing action most supports patient-centered care?
A. Limiting patient involvement in decisions
B. Applying standardized care without modification
C. Incorporating patient goals into the care plan
D. Prioritizing cost reduction over outcomes
Correct Answer: C
Rationale: Patient-centered care requires aligning treatment
plans with individual patient values and goals.
Citation: Harrison’s, 22nd ed., Ch. 1
3. Promoting Good Health
Which factor is most strongly associated with reduced
morbidity across populations?
A. Advanced diagnostic imaging
B. Lifestyle modification
C. Increased specialty referrals
D. Expanded pharmacotherapy
Correct Answer: B
Rationale: Health promotion emphasizes lifestyle factors (diet,
exercise, smoking cessation) as major determinants of long-
,term outcomes.
Citation: Harrison’s, 22nd ed., Ch. 2 – Promoting Good Health
4. Promoting Good Health
Which nursing intervention best reflects primary prevention?
A. Blood glucose monitoring
B. Smoking cessation counseling
C. Cardiac rehabilitation
D. Pain management
Correct Answer: B
Rationale: Primary prevention aims to prevent disease before it
occurs through risk reduction.
Citation: Harrison’s, 22nd ed., Ch. 2
5. Vaccine Opposition and Hesitancy
Which factor most commonly contributes to vaccine
hesitancy?
A. Lack of vaccine availability
B. Concerns about safety and trust
C. Provider recommendation
D. Genetic variability
Correct Answer: B
Rationale: Harrison’s identifies safety concerns, misinformation,
and distrust as major drivers of hesitancy.
, Citation: Harrison’s, 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
6. Vaccine Opposition and Hesitancy
What is the nurse’s most effective role in addressing vaccine
hesitancy?
A. Avoiding discussion
B. Providing clear, empathetic education
C. Enforcing vaccination
D. Referring all questions to physicians
Correct Answer: B
Rationale: Trust-building and respectful communication are
essential to improving vaccine acceptance.
Citation: Harrison’s, 22nd ed., Ch. 3
7. Decision-Making in Clinical Medicine
Which concept is central to shared decision-making?
A. Clinician authority
B. Patient autonomy with informed consent
C. Algorithm-based care
D. Cost minimization
Correct Answer: B
Rationale: Shared decision-making balances medical evidence
with patient values and informed choice.
