NURS 3365 COMPREHENSIVE 2026 EXAM QUESTIONS
AND ANSWERS RATED A+
✔✔Significant drug interactions (beta 1 blockers, digoxin, and calcium channel
blockers)- - ✔✔They all slow the heart rate.
✔✔Alpha 1 blockers - ✔✔Vasodilate- Prototype phentolamine (Regitine) and tamsulosin
(Flomax)
✔✔What happens to BP in vasodilation. - ✔✔BP decreases
✔✔What happens to heart rate when BP drops? - ✔✔HR increases
✔✔side effects of Alpha 1 blocker - ✔✔Orthostatic hypotension
✔✔Uses of Alpha blockers - ✔✔Used in hypertension ( doxazosin(Cardura)and can be
used in BPH. Used only for benign prostatic hyperplasia (BPH) tamsulosin (Flomax)
✔✔Alpha 2 agonist prototype - ✔✔clonidine
✔✔Where does this drug work? What does it do? - ✔✔Pre-synaptic- blocks release of
norepinephrine - helps reduce circulating norepinephrine - therefore helps lower BP
✔✔What is the relationship of CO to blood pressure? - ✔✔Orthostasis with first few
doses
✔✔Beta blockers non selective - ✔✔proranolol
✔✔beta blockers selective - ✔✔atenalol
✔✔ Parmacogenetics - ✔✔the study of genetic differences in drug responses when
referring to one gene
✔✔Pharmacogenomics - ✔✔the study of variances in drug response when studying all
genes
✔✔Phenotype - ✔✔physical appearance/function from the genotype/environment
✔✔Genetic polymorphism - ✔✔differences in alleles usually a single nucleotide
variation that causes a person to respond differently to a drug.
✔✔drug polymorphism - ✔✔effect of a patient's age, gender, size, body composition
and other characteristics on the pharmacokinetics of specific drugs
, ✔✔What are the difference regarding FDA approval for prescription, OTC, herbal
supplements - ✔✔Prescription and OTC are FDA approved and Herbal supplements
are NOT FDA approve can cause side effects
✔✔Clinical trials 1 - ✔✔pharmacokinetics and metabolism
✔✔clinical trials 2 - ✔✔effectiveness and adverse effect
✔✔clinical trials 3 - ✔✔safety, effectiveness, and dosage range
✔✔clinical trials 4 - ✔✔post marketing
✔✔When can drugs be prescribed to the general public - ✔✔after it pass phase 3
✔✔What do control substance schedule mean? - ✔✔abuse and dependency
✔✔Which pregnancy class is safe to use - ✔✔class A
✔✔which pregnancy class you should never use - ✔✔class X
✔✔How do genetic polymorphism impact drug therapy - ✔✔changes to DNA outside
the nucleus to determine the treatment outcome of a pharmacologic agent
✔✔Generic drug name - ✔✔safest, FDA approve, unique
✔✔trade name - ✔✔can be more than one, pharmaceutical name it
✔✔drug formulation - ✔✔liquid and solids
✔✔4 pharmacokinetic processes - ✔✔Absorption
Distribution
Metabolism
Elimination
✔✔bioavailabilty - ✔✔extent of absorption
✔✔effect of food and absorption - ✔✔slower absorption
✔✔what is the issues with enteric coated tablets and time release medication - ✔✔do
not chew or crush
✔✔suspension vs solution - ✔✔suspension particles settle and you have to shake it and
the solution is homogeneous
AND ANSWERS RATED A+
✔✔Significant drug interactions (beta 1 blockers, digoxin, and calcium channel
blockers)- - ✔✔They all slow the heart rate.
✔✔Alpha 1 blockers - ✔✔Vasodilate- Prototype phentolamine (Regitine) and tamsulosin
(Flomax)
✔✔What happens to BP in vasodilation. - ✔✔BP decreases
✔✔What happens to heart rate when BP drops? - ✔✔HR increases
✔✔side effects of Alpha 1 blocker - ✔✔Orthostatic hypotension
✔✔Uses of Alpha blockers - ✔✔Used in hypertension ( doxazosin(Cardura)and can be
used in BPH. Used only for benign prostatic hyperplasia (BPH) tamsulosin (Flomax)
✔✔Alpha 2 agonist prototype - ✔✔clonidine
✔✔Where does this drug work? What does it do? - ✔✔Pre-synaptic- blocks release of
norepinephrine - helps reduce circulating norepinephrine - therefore helps lower BP
✔✔What is the relationship of CO to blood pressure? - ✔✔Orthostasis with first few
doses
✔✔Beta blockers non selective - ✔✔proranolol
✔✔beta blockers selective - ✔✔atenalol
✔✔ Parmacogenetics - ✔✔the study of genetic differences in drug responses when
referring to one gene
✔✔Pharmacogenomics - ✔✔the study of variances in drug response when studying all
genes
✔✔Phenotype - ✔✔physical appearance/function from the genotype/environment
✔✔Genetic polymorphism - ✔✔differences in alleles usually a single nucleotide
variation that causes a person to respond differently to a drug.
✔✔drug polymorphism - ✔✔effect of a patient's age, gender, size, body composition
and other characteristics on the pharmacokinetics of specific drugs
, ✔✔What are the difference regarding FDA approval for prescription, OTC, herbal
supplements - ✔✔Prescription and OTC are FDA approved and Herbal supplements
are NOT FDA approve can cause side effects
✔✔Clinical trials 1 - ✔✔pharmacokinetics and metabolism
✔✔clinical trials 2 - ✔✔effectiveness and adverse effect
✔✔clinical trials 3 - ✔✔safety, effectiveness, and dosage range
✔✔clinical trials 4 - ✔✔post marketing
✔✔When can drugs be prescribed to the general public - ✔✔after it pass phase 3
✔✔What do control substance schedule mean? - ✔✔abuse and dependency
✔✔Which pregnancy class is safe to use - ✔✔class A
✔✔which pregnancy class you should never use - ✔✔class X
✔✔How do genetic polymorphism impact drug therapy - ✔✔changes to DNA outside
the nucleus to determine the treatment outcome of a pharmacologic agent
✔✔Generic drug name - ✔✔safest, FDA approve, unique
✔✔trade name - ✔✔can be more than one, pharmaceutical name it
✔✔drug formulation - ✔✔liquid and solids
✔✔4 pharmacokinetic processes - ✔✔Absorption
Distribution
Metabolism
Elimination
✔✔bioavailabilty - ✔✔extent of absorption
✔✔effect of food and absorption - ✔✔slower absorption
✔✔what is the issues with enteric coated tablets and time release medication - ✔✔do
not chew or crush
✔✔suspension vs solution - ✔✔suspension particles settle and you have to shake it and
the solution is homogeneous
