NSG5003 Week 3 Quiz
Study online at https://quizlet.com/_6gijx4
1. Inserting bone marrow cells into an individual who produces abnormal ery-
throcytes is an example of what type of therapy?: Somatic cell
2. DNA replication requires the enzyme DNA polymerase to:: Travel along the single DNA
strand, adding the correct nucleotide to the new strand
3. Transcription is best defined as a process by which:: RNA is synthesized from a DNA
template.
4. The purpose of a staining technique of chromosomes such as Giemsa is
to:: Allow for the numbering of chromosomes and the identification of variations.
5. An amniocentesis indicates a neural tube defect when an increase in which
protein is evident?: Alpha fetoprotein
6. An amniocentesis is recommended for pregnant women who:: Have a family history
of genetic disorders
7. The most clinically useful technique for prenatal diagnosis of chromosomal
abnormalities at 3 months' (12 weeks') gestation is:: Chorionic villus sampling
8. The term for an error in which homologous chromosomes fail to separate
during meiosis or mitosis is:: Nondisjunction
9. Which clinical manifestations would be expected for a child who has complete
trisomy of the twenty-first chromosome?: An IQ of 25 to 70, low nasal bridge, protruding tongue,
and flat, low-set ears
10. What is the most common cause of Down syndrome?: Maternal nondisjunction
11. What syndrome, characterized by an absent homologous X chromosome
with only a single X chromosome, exhibits features that include a short stature,
widely spaced nipples, and webbed neck?: Cri du chat
12. A person with 47, XXY karyotype has the genetic disorder resulting in which
syndrome?: Klinefelter
13. What is the chromosomal variation that causes Klinefelter syndrome?: Nondis-
junction of X chromosome in the mother
14. What is the second most commonly recognized genetic cause of mental
retardation?: Fragile X syndrome
15. What is the blood type of a person who is heterozygous, having A and B
alleles as codominant?: AB
, NSG5003 Week 3 Quiz
Study online at https://quizlet.com/_6gijx4
16. A couple has two children diagnosed with an autosomal dominant genetic
disease. What is the probability that the next child will have the same genetic
disease?: One half
17. When a child inherits a disease that is autosomal recessive, it is inherited
from:: Both parents
18. People diagnosed with neurofibromatosis have varying degrees of the con-
dition because of the genetic principle of:: Expressivity
19. Which genetic disease has been linked to a mutation of the tumor-suppres-
sor gene?: Retinoblastoma
20. Cystic fibrosis is caused by what type of gene?: Autosomal recessive
21. Which is an important criterion for discerning autosomal recessive inheri-
tance?: Consanguinity is sometimes present.
22. Consanguinity refers to the mating of persons:: Having common family relations
23. Males, having only one X chromosome (as is expected), are said to be:: Hem-
izygous
24. Males are more often affected by which type of genetic disease?: Sex-linked
recessive
25. An X-linked recessive disease can skip generations because:: The disease can be
transmitted through female carriers.
26. The presence of a zygote having one chromosome with the normal comple-
ment of genes and one with a missing gene is characteristic of which genetic
disorder?: Cri du chat
27. A child with which genetic disorder has a characteristic cry?: Cri du chat
28. Which statement is true regarding X-linked recessive conditions?: These condi-
tions are passed from affected father to all of his female children.
29. DNA formation occurs in which of the cell's structures?: Nucleus
30. What is the risk for the recurrence of autosomal dominant diseases?: 50%
31. An individual's genetic makeup is referred to as his or her:: Genotype
32. Which disorders have similar modes of inheritance? (Select all that: Duchenne
muscular dystrophy
Down syndrome
Study online at https://quizlet.com/_6gijx4
1. Inserting bone marrow cells into an individual who produces abnormal ery-
throcytes is an example of what type of therapy?: Somatic cell
2. DNA replication requires the enzyme DNA polymerase to:: Travel along the single DNA
strand, adding the correct nucleotide to the new strand
3. Transcription is best defined as a process by which:: RNA is synthesized from a DNA
template.
4. The purpose of a staining technique of chromosomes such as Giemsa is
to:: Allow for the numbering of chromosomes and the identification of variations.
5. An amniocentesis indicates a neural tube defect when an increase in which
protein is evident?: Alpha fetoprotein
6. An amniocentesis is recommended for pregnant women who:: Have a family history
of genetic disorders
7. The most clinically useful technique for prenatal diagnosis of chromosomal
abnormalities at 3 months' (12 weeks') gestation is:: Chorionic villus sampling
8. The term for an error in which homologous chromosomes fail to separate
during meiosis or mitosis is:: Nondisjunction
9. Which clinical manifestations would be expected for a child who has complete
trisomy of the twenty-first chromosome?: An IQ of 25 to 70, low nasal bridge, protruding tongue,
and flat, low-set ears
10. What is the most common cause of Down syndrome?: Maternal nondisjunction
11. What syndrome, characterized by an absent homologous X chromosome
with only a single X chromosome, exhibits features that include a short stature,
widely spaced nipples, and webbed neck?: Cri du chat
12. A person with 47, XXY karyotype has the genetic disorder resulting in which
syndrome?: Klinefelter
13. What is the chromosomal variation that causes Klinefelter syndrome?: Nondis-
junction of X chromosome in the mother
14. What is the second most commonly recognized genetic cause of mental
retardation?: Fragile X syndrome
15. What is the blood type of a person who is heterozygous, having A and B
alleles as codominant?: AB
, NSG5003 Week 3 Quiz
Study online at https://quizlet.com/_6gijx4
16. A couple has two children diagnosed with an autosomal dominant genetic
disease. What is the probability that the next child will have the same genetic
disease?: One half
17. When a child inherits a disease that is autosomal recessive, it is inherited
from:: Both parents
18. People diagnosed with neurofibromatosis have varying degrees of the con-
dition because of the genetic principle of:: Expressivity
19. Which genetic disease has been linked to a mutation of the tumor-suppres-
sor gene?: Retinoblastoma
20. Cystic fibrosis is caused by what type of gene?: Autosomal recessive
21. Which is an important criterion for discerning autosomal recessive inheri-
tance?: Consanguinity is sometimes present.
22. Consanguinity refers to the mating of persons:: Having common family relations
23. Males, having only one X chromosome (as is expected), are said to be:: Hem-
izygous
24. Males are more often affected by which type of genetic disease?: Sex-linked
recessive
25. An X-linked recessive disease can skip generations because:: The disease can be
transmitted through female carriers.
26. The presence of a zygote having one chromosome with the normal comple-
ment of genes and one with a missing gene is characteristic of which genetic
disorder?: Cri du chat
27. A child with which genetic disorder has a characteristic cry?: Cri du chat
28. Which statement is true regarding X-linked recessive conditions?: These condi-
tions are passed from affected father to all of his female children.
29. DNA formation occurs in which of the cell's structures?: Nucleus
30. What is the risk for the recurrence of autosomal dominant diseases?: 50%
31. An individual's genetic makeup is referred to as his or her:: Genotype
32. Which disorders have similar modes of inheritance? (Select all that: Duchenne
muscular dystrophy
Down syndrome
