Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Integrated MCQ Set (Chapters 1–13)
1. The Practice of Medicine
Q1. Which principle best defines modern evidence-based
medical practice?
A. Reliance on expert opinion
B. Exclusive use of randomized trials
C. Integration of best evidence with clinical expertise and
patient values
D. Prioritization of cost over outcomes
Answer: C
Rationale: Evidence-based medicine integrates scientific
evidence, clinician judgment, and patient preferences.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Promoting Good Health
Q2. Which nursing intervention most directly supports primary
prevention?
,A. Managing complications of chronic disease
B. Early detection of asymptomatic disease
C. Counseling on smoking cessation
D. Rehabilitation after injury
Answer: C
Rationale: Primary prevention aims to prevent disease before
onset through risk reduction.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine Opposition and Hesitancy
Q3. A key driver of vaccine hesitancy is:
A. Lack of vaccine availability
B. Mistrust in healthcare systems
C. Increased disease severity
D. Mandatory vaccination laws
Answer: B
Rationale: Harrison’s emphasizes mistrust and misinformation
as central contributors to hesitancy.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
Q4. Shared decision-making is most appropriate when:
A. One option clearly dominates
, B. Outcomes are preference-sensitive
C. The patient lacks decisional capacity
D. Emergency intervention is required
Answer: B
Rationale: Preference-sensitive decisions benefit from shared
deliberation.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
Q5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Standardize care across populations
C. Tailor treatment based on individual variability
D. Reduce diagnostic testing
Answer: C
Rationale: Genomic and biologic variability guide individualized
therapy.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
Q6. An effective screening test must demonstrate:
A. High cost-effectiveness only
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Integrated MCQ Set (Chapters 1–13)
1. The Practice of Medicine
Q1. Which principle best defines modern evidence-based
medical practice?
A. Reliance on expert opinion
B. Exclusive use of randomized trials
C. Integration of best evidence with clinical expertise and
patient values
D. Prioritization of cost over outcomes
Answer: C
Rationale: Evidence-based medicine integrates scientific
evidence, clinician judgment, and patient preferences.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Promoting Good Health
Q2. Which nursing intervention most directly supports primary
prevention?
,A. Managing complications of chronic disease
B. Early detection of asymptomatic disease
C. Counseling on smoking cessation
D. Rehabilitation after injury
Answer: C
Rationale: Primary prevention aims to prevent disease before
onset through risk reduction.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine Opposition and Hesitancy
Q3. A key driver of vaccine hesitancy is:
A. Lack of vaccine availability
B. Mistrust in healthcare systems
C. Increased disease severity
D. Mandatory vaccination laws
Answer: B
Rationale: Harrison’s emphasizes mistrust and misinformation
as central contributors to hesitancy.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Decision-Making in Clinical Medicine
Q4. Shared decision-making is most appropriate when:
A. One option clearly dominates
, B. Outcomes are preference-sensitive
C. The patient lacks decisional capacity
D. Emergency intervention is required
Answer: B
Rationale: Preference-sensitive decisions benefit from shared
deliberation.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
Q5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Standardize care across populations
C. Tailor treatment based on individual variability
D. Reduce diagnostic testing
Answer: C
Rationale: Genomic and biologic variability guide individualized
therapy.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. Screening and Prevention of Disease
Q6. An effective screening test must demonstrate:
A. High cost-effectiveness only
