Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The primary goal of evidence-based medical practice is to:
A. Replace clinical experience with guidelines
B. Integrate best evidence with clinical expertise and patient
values
C. Standardize care regardless of patient context
D. Minimize costs through protocol adherence
Correct Answer: B
Rationale: Evidence-based practice combines high-quality
evidence, clinician expertise, and patient preferences to
optimize outcomes.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Which intervention has the greatest population-level impact
on health outcomes?
,A. Advanced diagnostic imaging
B. Individual pharmacologic therapy
C. Public health prevention strategies
D. Specialized surgical care
Correct Answer: C
Rationale: Preventive and public health interventions produce
the largest reductions in morbidity and mortality at the
population level.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine hesitancy most commonly arises from:
A. Lack of vaccine availability
B. Religious doctrine alone
C. Mistrust appears driven by safety concerns and
misinformation
D. Proven vaccine ineffectiveness
Correct Answer: C
Rationale: Safety concerns, misinformation, and mistrust are
the dominant drivers of vaccine hesitancy.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Shared decision-making is BEST defined as:
, A. Physician-directed treatment selection
B. Patient choice without clinician input
C. Collaborative decision based on evidence and patient goals
D. Legal consent documentation
Correct Answer: C
Rationale: Shared decision-making aligns clinical evidence with
patient preferences and values.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision medicine primarily aims to:
A. Reduce clinician workload
B. Tailor care based on genetic, environmental, and lifestyle
factors
C. Replace traditional diagnostics
D. Limit care to specialized centers
Correct Answer: B
Rationale: Precision medicine individualizes care using biologic
and contextual patient data.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. A core nursing implication of screening programs is to:
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The primary goal of evidence-based medical practice is to:
A. Replace clinical experience with guidelines
B. Integrate best evidence with clinical expertise and patient
values
C. Standardize care regardless of patient context
D. Minimize costs through protocol adherence
Correct Answer: B
Rationale: Evidence-based practice combines high-quality
evidence, clinician expertise, and patient preferences to
optimize outcomes.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine
2. Which intervention has the greatest population-level impact
on health outcomes?
,A. Advanced diagnostic imaging
B. Individual pharmacologic therapy
C. Public health prevention strategies
D. Specialized surgical care
Correct Answer: C
Rationale: Preventive and public health interventions produce
the largest reductions in morbidity and mortality at the
population level.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health
3. Vaccine hesitancy most commonly arises from:
A. Lack of vaccine availability
B. Religious doctrine alone
C. Mistrust appears driven by safety concerns and
misinformation
D. Proven vaccine ineffectiveness
Correct Answer: C
Rationale: Safety concerns, misinformation, and mistrust are
the dominant drivers of vaccine hesitancy.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy
4. Shared decision-making is BEST defined as:
, A. Physician-directed treatment selection
B. Patient choice without clinician input
C. Collaborative decision based on evidence and patient goals
D. Legal consent documentation
Correct Answer: C
Rationale: Shared decision-making aligns clinical evidence with
patient preferences and values.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine
5. Precision medicine primarily aims to:
A. Reduce clinician workload
B. Tailor care based on genetic, environmental, and lifestyle
factors
C. Replace traditional diagnostics
D. Limit care to specialized centers
Correct Answer: B
Rationale: Precision medicine individualizes care using biologic
and contextual patient data.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care
6. A core nursing implication of screening programs is to:
