GMS 6474 MODULE 3- Cardiac Channels EXAM QUESTIONS WITH ANSWERS

GMS 6474 MODULE 3- Cardiac Channels |\ |\ |\ |\ |\ |\




EXAM QUESTIONS WITH ANSWERS |\ |\ |\




Define Equilibrium Potential - CORRECT ANSWERS ✔✔For
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a given ion the membrane electrical potential at which
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inward flow of that ion is equal to its outward flow.
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What is the Nerst equation? - CORRECT ANSWERS ✔✔E
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ion = -61/Z log10 ( [conc] inside/ [conc] out)
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For the electrical activity of the heart, the concentration
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of K is ________ inside the cell than outside.
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The electrical potential does what to K ions
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Reasoning? - CORRECT ANSWERS ✔✔Higher |\ |\ |\ |\




pulls K+ in because the interior of the cell is more
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negative.


For the electrical activity of the heart, the concentration
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of Na is ________ inside the cell than outside.
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The electrical potential does what to K ions
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, Reasoning? - CORRECT ANSWERS ✔✔Lower |\ |\ |\ |\




pushes Na out of the cell because the outside is more
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negative


Membrane potential across heart cell membranes (mV): |\ |\ |\ |\ |\ |\




Na+
K+
Ca2+ - CORRECT ANSWERS ✔✔Na+ = +60mV
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K+ = -90mV
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Ca2+ = +130mV |\ |\




Ion gradients across heart cell membranes
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Na+
K+
Ca2+ - CORRECT ANSWERS ✔✔Na = in 15 mM out
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150mM
K = in 150 mM out 5mM
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Ca = .in 0001 mM out 2mM
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What are the main ion channels involved in membrane
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excitation in the cardiac muscle? - CORRECT ANSWERS |\ |\ |\ |\ |\ |\ |\ |\



✔✔Na, K and Ca ions |\ |\ |\ |\