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Exam (elaborations)

Nur 376: Exam 1 Blueprint Complete Exam Review With Verified Answers | Latest 2025–2026 Edition

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NUR 376: EXAM 1 BLUEPRINT COMPLETE EXAM REVIEW WITH VERIFIED ANSWERS | LATEST 2025–2026 EDITION

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✓ NUR 376: EXAM 1 BLUEPRINT COMPLETE EXAM REVIEW
WITH VERIFIED ANSWERS | LATEST 2025–2026 EDITION
Vascular permeability - correct answer -1st response- inflammation mediators (histamines &
bradykinins) cause vessels to dilate & become more permeable, enabling WBC's & platelets to
site of injury



Cellular Chemotaxis - correct answer -body releases chemical that dispatch WBC's & platelets



Systemic Responses - correct answer -FEVER*, pain, sleepiness, lethargy, anemia, & weight loss



Titer - correct answer -the level of antibody within the bloodstream, usually corresponds with
to the level of exposure to the microbe

TB, rubella, any vaccines...



Positive means you have been exposed through infection or vaccine!



HIV - correct answer -attacks CD4 cells- normal range 800-1200 cells/mm^3



Becomes significant when below 500, below 200= aids



E-coli - correct answer -bacteria are acquired by the fecal-oral route, usually in food or
contaminated

water. The bacteria live in the intestines of healthy cattle.



Immunocompetence - correct answer -an individual's ability to protect oneself from infectious
agents because of a strong immune system

,From a young age builds immune defenses & swiftly eliminates many microorganisms as threats
of infection



immunosuppression - correct answer -indicates that there is a defective immune system that is
placing a person at risk for infections.



opportunistic infection - correct answer -which is an infection caused by a microorganism that
flourishes because of a host's deficient immune system



hospital-acquired infection - correct answer -A patient infection caused by microorganisms that
originated within the clinical environment



Difficult to treat bc often caused by antibiotic-resistant bacteria



Type I immediate hypersensitivity - correct answer -Allergy; person produces many IgE
antibodies against a specific allergen

Occurs minutes after contact with allergen; histamine is released

Symptoms include hives, hay fever, asthma, eczema, gastric disturbances, and anaphylactic
shock (a life-threatening severe form)



Type II cytotoxic hypersensitivity - correct answer -Igs attack antigens on cell surface

Antibody-mediated cell lysis results

Blood transfusion reaction is an example of a Type II hypersensitivity



Type III immune complex disorders - correct answer -occur when antigen combines with Ig
within circulation and these complexes are then deposited in tissues



autoimmine disorders

, Type IV delayed hypersensitivity - correct answer -T cell mediated

Previous exposure to antigen primes the T cells

T cell attack does not occur until days after initial exposure (delayed)

Example: poison ivy, transplant rejection

Mantoux test for tuberculosis demonstrates a Type IV hypersensitivity



SLE (systemic lupis erythemantous)-Etiology - correct answer -Cause unknown, risk factors-
genetic predisposition and environmental, estrogen hormones (commonly occurs in women 14-
45-SN), and immunological elements



SLE (systemic lupis erythemantous)- patho - correct answer -Antibodies form immune
complexes that are deposited in organs & tissues such as the skin, heart, joint synovial
membranes, glomeruli of the kidney & lungs

This deposit of immune complexes triggers an inflammation reaction that damages small blood
vessels and various organ membranes

The kidneys are particularly susceptible to inflammation in SLE, termed as

Lupus nephritis.

The lungs also commonly succumb to inflammatory changes such as pneumonitis, pleuritic, and
pulmonary hypertension.

Cardiac involvement in individuals with SLE can cause pericarditis,

endocarditis, and coronary artery disease.



SLE (systemic lupis erythemantous)- clinical manifestations - correct answer -S/S- butterfly rash
(cheeks & nose), fever (higher than 100F- REPORT), joints- painful & swollen (SN)



Labs- (SN)

Creatinine over 1.3 = bad kidney (kidneys hit the hardest)

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