WGU D027 Practice Exam – Questions &
Review | Latest Update 2026 | Graded A+
What organ does cystic fibrosis affect? - correct answerAffects the pancreas causing
secretions into the lungs
What is Klinefelter syndrome? - correct answerAn extra X chromosome for males so
example XXY causing female-like qualities
What is Turner Syndrome? - correct answerfemales. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection, language and
articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - correct answera condition in which the synthesis of the
beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - correct
answerFerrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia).
Directly toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for
hormone receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and
recurrence risk) - correct answerGlucocorticoids
What is the normal ejection fraction? - correct answer55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - correct answerPreserved
What are symptoms of left sided heart failure? - correct answerThink PULMONARY.
JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - correct answerThink peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - correct answerBNP. Heart failure is
a result greater than 100
What heart disease is worse with exertion? - correct answerIschemic heart disease
because the demand requirements are higher.
What should you assess before giving Digoxin? - correct answerApical pulse
How should Warfarin be started? - correct answerStart initial dose at half to monitor the
effects
,What causes the destruction of alveolar walls? Air goes in but can't get out which leads
to hyperinflation - correct answerEmphysema
What causes excess mucus production and smooth muscle hypertrophy? - correct
answerBronchitis
What is a chronic inflammatory obstruction of bronchi? - correct answerAsthma,
Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump? - correct answerEndocrine disorder called
acromegaly (overproduction of growth hormone)
What causes Addison's disease? - correct answerDecreased glucocorticoid (due to
autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome? - correct answerexcess cortisol
What causes Grave's disease? - correct answeroverproduction of thyroid hormone.
HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? -
correct answerAt night to avoid orthostatic hypotension. Educate slow position changes
and lay down if needed.
What are side effects of ACE inhibitors? - correct answerdry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - correct
answerNonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - correct answerVerapamil
What side effect should you watch for in a patient taking a statin drug? - correct
answerMuscle pain which can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? -
correct answerThiazide diuretics
What type of drug is spironolactone? - correct answerpotassium sparing diuretic
Which type of insulin is the most painful during injection? - correct answerLantus (long-
acting)
, Why test glycosylated hemoglobin (HgbA1c)? - correct answerMost reliable assessment
of blood sugar over the past 3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - correct answerThe normal range of TSH
levels is 0.4 to 4.0 milli-international units per liter. If you're already being treated for a
thyroid disorder, the normal range is 0.5 to 3.0 milli-international units per liter. A value
ABOVE the normal range usually indicates hypothyroidism.
What lab test would we recommend for thyroid? - correct answerThyroid peroxidase
antibodies (TPO)
symptoms of hypothyroidism - correct answerBradycardia; cold intolerance; lethargy;
memory loss; dry skin; brittle dry hair; decreased appetite; weight gain; constipation;
increased serum lipids; decreased libido; erectile dysfunction
What if a newborn has hypothyroidism? - correct answerRequires replacement within a
few days and last for 3 years to prevent mental development changes and dwarfism.
What is Hashimoto's disease? - correct answerAn autoimmune cause of hypothyroid.
Symptoms include weight gain and fatigue.
Symptoms of hyperthyroidism (thyrotoxicosis) - correct answerTachyarrhythmias,
anxiety, insomnia, rapid flow/speech, hot
GRAVES DISEASE
how to treat grave's disease? - correct answerRemove or destroy thyroid tissue or
suppress with drug (methimazole or propylthiouracil)
Treat with Iodine-131
Beta blockers also used to suppress release of thyroid hormones and reduce HR.
What causes vasodilation, bronchoconstriction, and helps with memory and sleep? -
correct answerhistamine- 1
What are side effects of antihistamines? - correct answersedation (only H-1), dry mucus
membranes, urinary hesitancy, and constipation.
Which medication is given after an MI? - correct answerBeta blocker is given for 6
months to prevent another MI
When should medication reconciliation be done? - correct answerWithin 30 days of
discharge
Which drug class is used as the first line of treatment for depression? - correct
answerSSRIs because of the low side effects and effectiveness.
Review | Latest Update 2026 | Graded A+
What organ does cystic fibrosis affect? - correct answerAffects the pancreas causing
secretions into the lungs
What is Klinefelter syndrome? - correct answerAn extra X chromosome for males so
example XXY causing female-like qualities
What is Turner Syndrome? - correct answerfemales. missing or deformed x
chromosome. right hemisphere dysfunction, hearing loss, ear infection, language and
articulation disorders, visual spatial and attentional problems
What is beta thalassemia? - correct answera condition in which the synthesis of the
beta-globin chains is decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - correct
answerFerrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia).
Directly toxic to lymphoid tissues Selective estrogen receptor modulators (SERM) - for
hormone receptor positive and advanced breast cancer. (Tomaxafin - reduces risk and
recurrence risk) - correct answerGlucocorticoids
What is the normal ejection fraction? - correct answer55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - correct answerPreserved
What are symptoms of left sided heart failure? - correct answerThink PULMONARY.
JVD, FVO, rails, S3 murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - correct answerThink peripheral
vascular. Lower extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - correct answerBNP. Heart failure is
a result greater than 100
What heart disease is worse with exertion? - correct answerIschemic heart disease
because the demand requirements are higher.
What should you assess before giving Digoxin? - correct answerApical pulse
How should Warfarin be started? - correct answerStart initial dose at half to monitor the
effects
,What causes the destruction of alveolar walls? Air goes in but can't get out which leads
to hyperinflation - correct answerEmphysema
What causes excess mucus production and smooth muscle hypertrophy? - correct
answerBronchitis
What is a chronic inflammatory obstruction of bronchi? - correct answerAsthma,
Triggers cause mucus to clog bronchial tubes.
What causes an overbite and buffalo hump? - correct answerEndocrine disorder called
acromegaly (overproduction of growth hormone)
What causes Addison's disease? - correct answerDecreased glucocorticoid (due to
autoimmune destruction of adrenal cortex)
What causes Cushing's syndrome? - correct answerexcess cortisol
What causes Grave's disease? - correct answeroverproduction of thyroid hormone.
HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? -
correct answerAt night to avoid orthostatic hypotension. Educate slow position changes
and lay down if needed.
What are side effects of ACE inhibitors? - correct answerdry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - correct
answerNonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - correct answerVerapamil
What side effect should you watch for in a patient taking a statin drug? - correct
answerMuscle pain which can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? -
correct answerThiazide diuretics
What type of drug is spironolactone? - correct answerpotassium sparing diuretic
Which type of insulin is the most painful during injection? - correct answerLantus (long-
acting)
, Why test glycosylated hemoglobin (HgbA1c)? - correct answerMost reliable assessment
of blood sugar over the past 3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - correct answerThe normal range of TSH
levels is 0.4 to 4.0 milli-international units per liter. If you're already being treated for a
thyroid disorder, the normal range is 0.5 to 3.0 milli-international units per liter. A value
ABOVE the normal range usually indicates hypothyroidism.
What lab test would we recommend for thyroid? - correct answerThyroid peroxidase
antibodies (TPO)
symptoms of hypothyroidism - correct answerBradycardia; cold intolerance; lethargy;
memory loss; dry skin; brittle dry hair; decreased appetite; weight gain; constipation;
increased serum lipids; decreased libido; erectile dysfunction
What if a newborn has hypothyroidism? - correct answerRequires replacement within a
few days and last for 3 years to prevent mental development changes and dwarfism.
What is Hashimoto's disease? - correct answerAn autoimmune cause of hypothyroid.
Symptoms include weight gain and fatigue.
Symptoms of hyperthyroidism (thyrotoxicosis) - correct answerTachyarrhythmias,
anxiety, insomnia, rapid flow/speech, hot
GRAVES DISEASE
how to treat grave's disease? - correct answerRemove or destroy thyroid tissue or
suppress with drug (methimazole or propylthiouracil)
Treat with Iodine-131
Beta blockers also used to suppress release of thyroid hormones and reduce HR.
What causes vasodilation, bronchoconstriction, and helps with memory and sleep? -
correct answerhistamine- 1
What are side effects of antihistamines? - correct answersedation (only H-1), dry mucus
membranes, urinary hesitancy, and constipation.
Which medication is given after an MI? - correct answerBeta blocker is given for 6
months to prevent another MI
When should medication reconciliation be done? - correct answerWithin 30 days of
discharge
Which drug class is used as the first line of treatment for depression? - correct
answerSSRIs because of the low side effects and effectiveness.
