NBME 10 REVIEW ACTUAL EXAM 2026
COMPLETE QUESTIONS AND FULL
SOLUTIONS GRADED A+
⩥ Order of maturation in female. Answer: Thelarche, pubarcge, growth
spurt, menarche
⩥ 27-year-old man presents with thrombocytopenia, eczema and
recurrent infections. Answer: Wiskott-Aldrich, WAS gene,
⩥ Patient comes in with ulcerative colitis Treated with prednisone
mesalamine and much more and the doctor decides to add a regimen,
due to the addition of the regimen what should be tested next. Answer:
Tuberculosis screening, due to initiation of TNF alpha inhibitor
⩥ Patient with sickle cell disease comes in with vaso-occlusive crisis it
is given pain control what else should be given with the pain control?.
Answer: Intravenous fluids
⩥ Patient with a MI 10 years ago Comes to the hospital due to vomiting.
The patient ends up getting a transfusion and 30 minutes later starts
developing shortness of breath, what is the most likely cause?. Answer:
Transfusion associated circulatory overload
,Remember: patience with ABO incompatibility present with flank pain
and hypotension
⩥ Treatment of transfusion associate circulatory overload. Answer:
Oxygen and positive pressure ventilation And possible directions
⩥ Can lead to psychosis, bizarre behavior, agitation, aggression,
nystagmus and ataxia
treatment. Answer: PCP intoxication
Treatment: IM lorazepam or Midazolam
⩥ 38-year-old woman comes in due to seizures, MRI demonstrates
unilateral or bilateral temporal lobe abnormalities, what is the next best
step?. Answer: Lumbar puncture: HSV encephalitis
⩥ If a patient has stroke like symptoms occurring less than 4 1/2 half
hours Without signs of hemorrhage what is administered?. Answer:
Alteplase
⩥ If the patient comes in with a stroke in the amount of time is
unknown, with no evidence of hemorrhage what is administered?.
Answer: Aspirin instead of alteplase
⩥ Bell's palsy Presents with facial nerve palsy causing facial paralysis
that doesn't spread the forehead, what is the next best step?
, Treatment:. Answer: It's diagnose clinically, no further testing indicated
Treatment: glucocorticoids and occasionally antiviral therapy
⩥ Patient after gastric bypass presents with ataxia, altered mental status
and opthalmoplegia including nystagmus, most likely cause?. Answer:
Vit B1 def
⩥ Immunocompetent child with cervical lymphadenitis presents with a
purpleish hue, And presence of multiple granulomas on excisional
biopsy. Answer: Purpleish hue: mycobacterium infection
⩥ Patient presents with a 2 cm ulcer on the foot and new mid back pain,
what is the most likely cause and what is the next best step to confirm
the diagnosis?. Answer: Vertebral osteomyelitis, MRI of the lumbar
spine.
Can occur through hematogenous spread
⩥ Patient with a history of inflammatory joint disease are at increased
risk for. Answer: Septic arthritis
⩥ An x-ray showing periosteal elevation is diagnostics for osteomyelitis,
what is the next best step?. Answer: MRI before bone biopsy
COMPLETE QUESTIONS AND FULL
SOLUTIONS GRADED A+
⩥ Order of maturation in female. Answer: Thelarche, pubarcge, growth
spurt, menarche
⩥ 27-year-old man presents with thrombocytopenia, eczema and
recurrent infections. Answer: Wiskott-Aldrich, WAS gene,
⩥ Patient comes in with ulcerative colitis Treated with prednisone
mesalamine and much more and the doctor decides to add a regimen,
due to the addition of the regimen what should be tested next. Answer:
Tuberculosis screening, due to initiation of TNF alpha inhibitor
⩥ Patient with sickle cell disease comes in with vaso-occlusive crisis it
is given pain control what else should be given with the pain control?.
Answer: Intravenous fluids
⩥ Patient with a MI 10 years ago Comes to the hospital due to vomiting.
The patient ends up getting a transfusion and 30 minutes later starts
developing shortness of breath, what is the most likely cause?. Answer:
Transfusion associated circulatory overload
,Remember: patience with ABO incompatibility present with flank pain
and hypotension
⩥ Treatment of transfusion associate circulatory overload. Answer:
Oxygen and positive pressure ventilation And possible directions
⩥ Can lead to psychosis, bizarre behavior, agitation, aggression,
nystagmus and ataxia
treatment. Answer: PCP intoxication
Treatment: IM lorazepam or Midazolam
⩥ 38-year-old woman comes in due to seizures, MRI demonstrates
unilateral or bilateral temporal lobe abnormalities, what is the next best
step?. Answer: Lumbar puncture: HSV encephalitis
⩥ If a patient has stroke like symptoms occurring less than 4 1/2 half
hours Without signs of hemorrhage what is administered?. Answer:
Alteplase
⩥ If the patient comes in with a stroke in the amount of time is
unknown, with no evidence of hemorrhage what is administered?.
Answer: Aspirin instead of alteplase
⩥ Bell's palsy Presents with facial nerve palsy causing facial paralysis
that doesn't spread the forehead, what is the next best step?
, Treatment:. Answer: It's diagnose clinically, no further testing indicated
Treatment: glucocorticoids and occasionally antiviral therapy
⩥ Patient after gastric bypass presents with ataxia, altered mental status
and opthalmoplegia including nystagmus, most likely cause?. Answer:
Vit B1 def
⩥ Immunocompetent child with cervical lymphadenitis presents with a
purpleish hue, And presence of multiple granulomas on excisional
biopsy. Answer: Purpleish hue: mycobacterium infection
⩥ Patient presents with a 2 cm ulcer on the foot and new mid back pain,
what is the most likely cause and what is the next best step to confirm
the diagnosis?. Answer: Vertebral osteomyelitis, MRI of the lumbar
spine.
Can occur through hematogenous spread
⩥ Patient with a history of inflammatory joint disease are at increased
risk for. Answer: Septic arthritis
⩥ An x-ray showing periosteal elevation is diagnostics for osteomyelitis,
what is the next best step?. Answer: MRI before bone biopsy
