MEDICATION ADMINISTRATION TEST BANK
PREP 2026 ACCURATE QUESTIONS
VERIFIED
◉ Classification of medications. Answer: Based on:
- effects on body system
- symptoms relieved by medication
- medication's desired effect
◉ Pharmacokinetics. Answer: The study of how medications enter
the body, reach their site of action, metabolize, and exit the body.
ADME
◉ Absorption. Answer: Passage of medication molecules into the
blood from the site of administration
Factors that alter absorption:
- route
- ability of medication to dissolve
- blood flow to site of administration
- body surface area (increased surface area = increased absorption)
- lipid solubility of medication (BBB)
, ◉ Distribution. Answer: After absorbed, the medication is distributed
to body tissues/organs (the site of action)
Rate/extent depends on:
- physical/chemical properties of medication
- physiology of client
** circulation (blood flow to liver decreases with age)
** membrane permeability
** protein binding (decreased albumin with age)
◉ Metabolism. Answer: Metabolized into a less potent/inactive form
Biotransformation: enzymes detoxify, break down, & remove active
chemicals
Occurs mostly in the liver, but also in the kidneys, blood, intestines, &
lungs
◉ Excretion. Answer: Medications are excreted by the:
- kidneys
- liver
- bowel
- lungs
,- exocrine glands
Chemical makeup of medication determines organ of excretion
◉ Therapeutic effect. Answer: expected or predicted physiological
response that a medication causes
◉ Side effects. Answer: predictable and often unavoidable secondary
effects produced at a usual therapeutic dose
◉ Adverse effects. Answer: unintended, undesirable, and often
unpredictable severe responses to medication
◉ Toxic effects. Answer: develop after prolonged intake of a
medication or when a medication accumulates in the blood because of
impaired metabolism or excretion
◉ Idiosyncratic reaction. Answer: unpredictable effects
a patient overreacts or underreacts to a medication or has a reaction
different from normal
◉ Synergistic effect. Answer: combined effect of two medications is
greater than the effect of medications given separately
, ◉ Mild allergic reaction symptoms. Answer: Urticaria
Rash
Pruritus
Rhinitis
◉ Peak. Answer: time it takes for a medication to reach its highest
effective concentration
◉ Trough. Answer: minimum blood serum concentration of
medication reached just before the next scheduled dose
◉ Onset. Answer: time it takes after a medication is administered for
it to produce a response
◉ Duration. Answer: time during which the medication is present in
concentration great enough to produce a response
◉ Plateau. Answer: blood serum concentration of a medication
reached and maintained after repeated fixed doses
◉ Administration of otic medications. Answer: Children: upward &
backward pulling of pinna
Adults: downward & backward pulling of pinna
PREP 2026 ACCURATE QUESTIONS
VERIFIED
◉ Classification of medications. Answer: Based on:
- effects on body system
- symptoms relieved by medication
- medication's desired effect
◉ Pharmacokinetics. Answer: The study of how medications enter
the body, reach their site of action, metabolize, and exit the body.
ADME
◉ Absorption. Answer: Passage of medication molecules into the
blood from the site of administration
Factors that alter absorption:
- route
- ability of medication to dissolve
- blood flow to site of administration
- body surface area (increased surface area = increased absorption)
- lipid solubility of medication (BBB)
, ◉ Distribution. Answer: After absorbed, the medication is distributed
to body tissues/organs (the site of action)
Rate/extent depends on:
- physical/chemical properties of medication
- physiology of client
** circulation (blood flow to liver decreases with age)
** membrane permeability
** protein binding (decreased albumin with age)
◉ Metabolism. Answer: Metabolized into a less potent/inactive form
Biotransformation: enzymes detoxify, break down, & remove active
chemicals
Occurs mostly in the liver, but also in the kidneys, blood, intestines, &
lungs
◉ Excretion. Answer: Medications are excreted by the:
- kidneys
- liver
- bowel
- lungs
,- exocrine glands
Chemical makeup of medication determines organ of excretion
◉ Therapeutic effect. Answer: expected or predicted physiological
response that a medication causes
◉ Side effects. Answer: predictable and often unavoidable secondary
effects produced at a usual therapeutic dose
◉ Adverse effects. Answer: unintended, undesirable, and often
unpredictable severe responses to medication
◉ Toxic effects. Answer: develop after prolonged intake of a
medication or when a medication accumulates in the blood because of
impaired metabolism or excretion
◉ Idiosyncratic reaction. Answer: unpredictable effects
a patient overreacts or underreacts to a medication or has a reaction
different from normal
◉ Synergistic effect. Answer: combined effect of two medications is
greater than the effect of medications given separately
, ◉ Mild allergic reaction symptoms. Answer: Urticaria
Rash
Pruritus
Rhinitis
◉ Peak. Answer: time it takes for a medication to reach its highest
effective concentration
◉ Trough. Answer: minimum blood serum concentration of
medication reached just before the next scheduled dose
◉ Onset. Answer: time it takes after a medication is administered for
it to produce a response
◉ Duration. Answer: time during which the medication is present in
concentration great enough to produce a response
◉ Plateau. Answer: blood serum concentration of a medication
reached and maintained after repeated fixed doses
◉ Administration of otic medications. Answer: Children: upward &
backward pulling of pinna
Adults: downward & backward pulling of pinna
