NBME CBSE Practice Questions (1–100) Actual
Exam complete questions and answers newest
2026.
A 65-year-old man with a long smoking history presents
with weight loss and hemoptysis. Imaging shows a central
lung mass. Biopsy reveals sheets of small blue cells.
Answer: Small cell lung carcinoma
Rationale: Small cell carcinoma is centrally located,
associated with smoking, and composed of small blue
cells.
A patient with chronic alcoholism develops confusion,
ataxia, and ophthalmoplegia.
Answer: Wernicke encephalopathy
, Rationale: Thiamine deficiency causes the triad of
confusion, ataxia, and ophthalmoplegia.
A child presents with recurrent infections and absence of
a thymic shadow on chest X-ray.
Answer: DiGeorge syndrome
Rationale: Failure of 3rd and 4th pharyngeal pouch
development leads to thymic aplasia and T-cell
deficiency.
A patient develops weakness that improves with
repeated muscle use.
Answer: Lambert-Eaton syndrome
Rationale: Autoantibodies against presynaptic calcium
channels increase acetylcholine release with repeated
use.
A newborn has bilious vomiting and abdominal
distension shortly after birth.
Exam complete questions and answers newest
2026.
A 65-year-old man with a long smoking history presents
with weight loss and hemoptysis. Imaging shows a central
lung mass. Biopsy reveals sheets of small blue cells.
Answer: Small cell lung carcinoma
Rationale: Small cell carcinoma is centrally located,
associated with smoking, and composed of small blue
cells.
A patient with chronic alcoholism develops confusion,
ataxia, and ophthalmoplegia.
Answer: Wernicke encephalopathy
, Rationale: Thiamine deficiency causes the triad of
confusion, ataxia, and ophthalmoplegia.
A child presents with recurrent infections and absence of
a thymic shadow on chest X-ray.
Answer: DiGeorge syndrome
Rationale: Failure of 3rd and 4th pharyngeal pouch
development leads to thymic aplasia and T-cell
deficiency.
A patient develops weakness that improves with
repeated muscle use.
Answer: Lambert-Eaton syndrome
Rationale: Autoantibodies against presynaptic calcium
channels increase acetylcholine release with repeated
use.
A newborn has bilious vomiting and abdominal
distension shortly after birth.
