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Summary NUR 3128 Pharmacology: Antibiotics Fundamentals, Classes, MOA, Side Effects & Nursing Alerts

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2025/2026 Written for academic year
Institution University Of Florida College Of Nursing
Course NUR3128
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The document is a high yield guide that provides a complete summary of essential antibiotic fundamentals for nursing students with major classes, nursing priorities, patient education, NCLEX alerts and quick reference table. It breaks down complex pharmacological concepts into easy to read sections

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PHARMACOLOGY: ANTIBIOTICS — FUNDAMENTALS SUMMARY
Course fit: Pharmacology | Medical-Surgical Nursing | NCLEX-RN
Focus: Classes • MOA • Side Effects • Nursing Alerts • Patient Education

WHAT ARE ANTIBIOTICS?
Drugs that kill bacteria (bactericidal) or inhibit growth of bacteria (bacteriostatic).
❌ Do NOT treat viral infections.

ANTIBIOTIC CLASSES
1.Penicillins
2.Cephalosporins
3.Macrolides
4.Fluoroquionolones
5.Tetracycline
6.Aminoglycosides
7.Sulfonamides

1. Penicillins (-cillin)

Examples: amoxicillin, penicillin G
MOA: Inhibit cell wall synthesis → bacterial death
Side Effects: Allergy, Rash, Anaphylaxis (life-threatening)
Nursing Alerts:
 Check penicillin allergy
 Watch for cross-sensitivity (cephalosporins)
Patient Education:
 Take full course
 Report rash, itching, SOB immediately

2. Cephalosporins (cef- / ceph-)

Examples: ceftriaxone, cefazolin
MOA: Cell wall synthesis inhibition
Side Effects: GI upset, allergy
Nursing Alerts:
 Use caution with PCN allergy (cross-sensitivity)
Patient Education:
 Finish medication
 Report severe diarrhea (Clostridioides difficile risk)

3. Macrolides (-thromycin)

Examples: azithromycin, erythromycin
MOA: Inhibit protein synthesis (50S ribosome)
Side Effects: GI upset, QT prolongation
Nursing Alerts:
 Monitor ECG in cardiac patients
 Drug interactions common
Patient Education:
 Avoid antacids close to dosing


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