NU 578 Exam 1 Pharm Questions & Answers
1. When stimulated, the function of the alpha-2 receptor is
E. to increase heart rate and force of contraction
B. to dilate smooth muscle of the airways
D. to cause mydriasis
C. to reduce further release of neurotransmitter*
2. To assess the renal function of 72- year old, the apn knows to check which lab value. D.
Creatinine*
3. Drugs that are subject to extensive first-pass metabolism:
a. May be administered rectally and completely escape first-pass metabolism*
b. Require larger intravenous doses than oral doses
c. Cannot be given orally
d. May be more efficacious given by a parenteral route.
4. A 29 year old with hx of upper abdominal pain and tarry stools to determine to have
peptic ulcer disease. Pharmacologic therapy includes an anticholinergic drug. Upon taking
his medication which of the following assessment findings would be most likely in this
client?
Bradycardia,
, hyperactive bowel sounds,
dilated pupils,
tenesmus,
drooling.*
5. Drug metabolizing enzymes may be found primarily in the? A. brain b. kidney c.
intestinal lining
d. liver
6. With respect to drug metabolizing enzymes (DME). A. activity of drug metabolizing
enzymes in children does not really develop until one year of age b. activity of drug
metabolizing enzymes is the same in men and women for all drugs c P-Glycoprotein is
the main drug metabolizing enzymes in the liver d. these are found primarily in the gut
and kidneys. ?????
7. Termination of acetylcholine at the synaptic junction occur through degradation by.
Acetylcholinesterase
8. A patient is being evaluated in the emergency department with a differential diagnosis
of antimuscarinic poisoning versus psychosis. Which of the following signs and
symptoms will the nurse expect to see if the experiencing poison? A. hypothermia b.
cold, pale skin c. dry mouth d. salivation
1. When stimulated, the function of the alpha-2 receptor is
E. to increase heart rate and force of contraction
B. to dilate smooth muscle of the airways
D. to cause mydriasis
C. to reduce further release of neurotransmitter*
2. To assess the renal function of 72- year old, the apn knows to check which lab value. D.
Creatinine*
3. Drugs that are subject to extensive first-pass metabolism:
a. May be administered rectally and completely escape first-pass metabolism*
b. Require larger intravenous doses than oral doses
c. Cannot be given orally
d. May be more efficacious given by a parenteral route.
4. A 29 year old with hx of upper abdominal pain and tarry stools to determine to have
peptic ulcer disease. Pharmacologic therapy includes an anticholinergic drug. Upon taking
his medication which of the following assessment findings would be most likely in this
client?
Bradycardia,
, hyperactive bowel sounds,
dilated pupils,
tenesmus,
drooling.*
5. Drug metabolizing enzymes may be found primarily in the? A. brain b. kidney c.
intestinal lining
d. liver
6. With respect to drug metabolizing enzymes (DME). A. activity of drug metabolizing
enzymes in children does not really develop until one year of age b. activity of drug
metabolizing enzymes is the same in men and women for all drugs c P-Glycoprotein is
the main drug metabolizing enzymes in the liver d. these are found primarily in the gut
and kidneys. ?????
7. Termination of acetylcholine at the synaptic junction occur through degradation by.
Acetylcholinesterase
8. A patient is being evaluated in the emergency department with a differential diagnosis
of antimuscarinic poisoning versus psychosis. Which of the following signs and
symptoms will the nurse expect to see if the experiencing poison? A. hypothermia b.
cold, pale skin c. dry mouth d. salivation
