Immunology Exam 5 WEIGEL
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What different cells can become plasma cells. - Answer✅✅activated B cells ; isotype
switched, somatically hypermutated centrocytes ; memory B cells
What are the components of the B cell co-receptor - Answer✅✅CR2 ; CD19 ; CD81
= TAPA-1
What does CR1 do for the co-receptor?
Helps ________ to cleave __________ ; Binding of _____ (On the B-cell) to ______
(on the pathogen) makes it susceptible to cleavage to ______. _______ (part of the
B-cell co-receptor) can then bind to the ______. The signal is sent through ________.
- Answer✅✅factor I ; C3b>C3d ; CR1 ; C4b ; C4d ; CR2 ; C3d ; CD19
CR1 binds to ________ - Answer✅✅C4B
TI stands for _____________ ; TD stands for _______________ -
Answer✅✅Thymus independent ; Thymus dependent
, Describe B cell activation, CD40 ligand, CD40, NFkB, ICAM-1 and IL-4 secretion by T
cells.
For B cell activation the ______ must meet its appropriate antigen, and the co-
receptor, CD40 must meet _________ on a T cell. The CD40:CD40L interaction
causes the B cell to activate transcription factor _______, NFkB regulates
___________ and once NFkB is activated ________ is up regulated and expressed on
the B cell surface. ICAM-1 on the B cell surface then binds to ________ on the T cell
surface. Once these receptors have been connected the T cell begins to secrete
_______ onto the B cell surface. IL-4 is very important cytokine that drives
__________________. - Answer✅✅BCR ; CD40L ; NFkB ; ICAM-1 ; ICAM-1 ; LFA-1 ;
IL-4 ; B cell proliferation
Define: follicular dendritic cells (dark zone/light zone)
Characteristic ________________ cells of follicles in ________________ lymphoid
tissues. They have _________ branching processes that make intimate contact with
_____________ and have _____ and _____________ receptors that hold
antigen:antibody:complement complexes on their surfaces for long periods. These
cells are crucial in selecting _________________________ during antibody
responses. - Answer✅✅nonlymphoid ; secondary ; long ; B cells ; Fc ; complement ;
antigen-binding B cells
Dark Zone: Area in the _____________________ containing closely packed
____________________ (____%) - Answer✅✅germinal center ; centroblasts ; 80
Light Zone: Area in the _________________ containing _______________________
that will interact - Answer✅✅germinal center ; non-dividing centrocytes
How do antibodies function? Do they destroy the pathogen directly or do they tag
and cover up things?
Antibodies ______ destroy the pathogen directly. They do 3 things: ____________,
____________, and ____________ - Answer✅✅don't ; neutralization ;
opsonization ; complement activation
Neutralization: - Answer✅✅It covers up all the sites that the Ag would use to bind
with cells
Opsonization: - Answer✅✅Tagging pathogens for phagocytosis
Complement activation: - Answer✅✅Complement Activation of the classical
pathway
Antigen binding (does the B cell take up the antigen, what is this called)
Exam| Brand New Exam Questions
with 100% Correct Clear Verified
Answers| All Graded A+|Latest
Premium Update 2026|100%
Guaranteed Success.
What different cells can become plasma cells. - Answer✅✅activated B cells ; isotype
switched, somatically hypermutated centrocytes ; memory B cells
What are the components of the B cell co-receptor - Answer✅✅CR2 ; CD19 ; CD81
= TAPA-1
What does CR1 do for the co-receptor?
Helps ________ to cleave __________ ; Binding of _____ (On the B-cell) to ______
(on the pathogen) makes it susceptible to cleavage to ______. _______ (part of the
B-cell co-receptor) can then bind to the ______. The signal is sent through ________.
- Answer✅✅factor I ; C3b>C3d ; CR1 ; C4b ; C4d ; CR2 ; C3d ; CD19
CR1 binds to ________ - Answer✅✅C4B
TI stands for _____________ ; TD stands for _______________ -
Answer✅✅Thymus independent ; Thymus dependent
, Describe B cell activation, CD40 ligand, CD40, NFkB, ICAM-1 and IL-4 secretion by T
cells.
For B cell activation the ______ must meet its appropriate antigen, and the co-
receptor, CD40 must meet _________ on a T cell. The CD40:CD40L interaction
causes the B cell to activate transcription factor _______, NFkB regulates
___________ and once NFkB is activated ________ is up regulated and expressed on
the B cell surface. ICAM-1 on the B cell surface then binds to ________ on the T cell
surface. Once these receptors have been connected the T cell begins to secrete
_______ onto the B cell surface. IL-4 is very important cytokine that drives
__________________. - Answer✅✅BCR ; CD40L ; NFkB ; ICAM-1 ; ICAM-1 ; LFA-1 ;
IL-4 ; B cell proliferation
Define: follicular dendritic cells (dark zone/light zone)
Characteristic ________________ cells of follicles in ________________ lymphoid
tissues. They have _________ branching processes that make intimate contact with
_____________ and have _____ and _____________ receptors that hold
antigen:antibody:complement complexes on their surfaces for long periods. These
cells are crucial in selecting _________________________ during antibody
responses. - Answer✅✅nonlymphoid ; secondary ; long ; B cells ; Fc ; complement ;
antigen-binding B cells
Dark Zone: Area in the _____________________ containing closely packed
____________________ (____%) - Answer✅✅germinal center ; centroblasts ; 80
Light Zone: Area in the _________________ containing _______________________
that will interact - Answer✅✅germinal center ; non-dividing centrocytes
How do antibodies function? Do they destroy the pathogen directly or do they tag
and cover up things?
Antibodies ______ destroy the pathogen directly. They do 3 things: ____________,
____________, and ____________ - Answer✅✅don't ; neutralization ;
opsonization ; complement activation
Neutralization: - Answer✅✅It covers up all the sites that the Ag would use to bind
with cells
Opsonization: - Answer✅✅Tagging pathogens for phagocytosis
Complement activation: - Answer✅✅Complement Activation of the classical
pathway
Antigen binding (does the B cell take up the antigen, what is this called)
