Nuclear Medicine Exam Review
Questions and Answers
How does 201Tl decay? - ANS-by electron capture
What is the role of the stannous ion in the preparation of pharmaceuticals labeled with
99mTc? - ANS-to reduce the valence state of 99mTc
If an assay of a vial containing 131I shows 50 mCi present on May 2, approximately
what will the assay show on May 18? - ANS-12.5 mCi
If a bone scan has been ordered on a 5-year-old girl, and the physician prescribes 62%
of the adult dose to be
given, how many mCi should be administered? - ANS-12.4 mCi
If the biological half-life of an isotope is 6 hours, and the physical half-life is 12 hrs,what
is the effective half-life? - ANS-4 hrs
Which of the following has been used to abbreviate physical half-life?
a.Tp
b. T/2
c. T2
d. P 1/2 - ANS-a. Tp
A MAA kit contains 40 mCi of 99mTc in 5 ml at 8:00 a.m. What would be the best
volume to be withdraw at
10:00 a.m. if a perfusion lung scan is planned? (l = 0.794) - ANS-0.63 ml
What is the most likely size of an MAA particle if correctly prepared? - ANS-10-30 μm
99mTc MAA has a biologic half-life of 2-4 hours; what will the effective half-life be? -
ANS-1.5-2.4 hours
Which radiopharmaceutical is made with 99mTc without a reducing agent? - ANS-sulfur
colloid
Which of the following is an example of radiochemical impurity? - ANS-presence of free
99mTc in a preparation of 99mTc sulfur colloid
Which of the following can be said regarding effective half-life? - ANS-it always shorter
than both the physical and the biologic half-life
, The purpose of adding EDTA to sulfur colloid when labeling with 99mTc is: - ANS-to
bind excess Al3+ and to prevent loss of the radiolabel
A diphosphonate kit should generally be used within how many hours after preparation?
- ANS-4 hours
What is the usual particle size of sulfur colloid? - ANS-0.3-1.0 μm
Which radiopharmaceutical,when correctly prepared, will have the smallest particle
size? - ANS-99mTc human serum albumin
The advantages of albumin colloid over sulfur colloid include: - ANS-does not require
boiling
Following injection of 99mTc MAA for a perfusion lung scan, activity is seen in the
kidneys and brain. This is
indicative of: - ANS-right to left cardiac shunt
At 7:00 a.m., a technologist prepares a dose of 99mTcMDP for injection at 10:00 a.m.
that day. The desired
dose is 22 mCi and no precalibration factors are available. The three hour decay factor
for the isotope is 0.707. What amount of activity should the technologist draw up into the
syringe at 7:00 a.m.? - ANS-31.1 mCi
What can be said regarding precalibration factors? - ANS-it is not necessary for problem
solving if the decay factor is available, and it is always >1.0
What method is used to calculate pediatric dose?
a. according to weight
b. Clark's formula
c. according to body surface area
d. using Talbot's nomogram
e. all of the above - ANS-e. all of the above
If the recommended volume for a MAG3 kit ranges from
4-10 ml, and the 99mTc eluate that will be used contains
820 mCi in 10 ml, and 41 mCi will be used,what is the
minimum amount of diluent that should be added? - ANS-3.5 ml
If a 20 mCi dose of 99mTc HDP are needed at 9:00 a.m.,how much activity should the
syringe contain if the technologist prepares it at 7:00 a.m.? - ANS-25.18 mCi
Determine the decay factor for 99mTc
at 7 hours. - ANS-0.445
Questions and Answers
How does 201Tl decay? - ANS-by electron capture
What is the role of the stannous ion in the preparation of pharmaceuticals labeled with
99mTc? - ANS-to reduce the valence state of 99mTc
If an assay of a vial containing 131I shows 50 mCi present on May 2, approximately
what will the assay show on May 18? - ANS-12.5 mCi
If a bone scan has been ordered on a 5-year-old girl, and the physician prescribes 62%
of the adult dose to be
given, how many mCi should be administered? - ANS-12.4 mCi
If the biological half-life of an isotope is 6 hours, and the physical half-life is 12 hrs,what
is the effective half-life? - ANS-4 hrs
Which of the following has been used to abbreviate physical half-life?
a.Tp
b. T/2
c. T2
d. P 1/2 - ANS-a. Tp
A MAA kit contains 40 mCi of 99mTc in 5 ml at 8:00 a.m. What would be the best
volume to be withdraw at
10:00 a.m. if a perfusion lung scan is planned? (l = 0.794) - ANS-0.63 ml
What is the most likely size of an MAA particle if correctly prepared? - ANS-10-30 μm
99mTc MAA has a biologic half-life of 2-4 hours; what will the effective half-life be? -
ANS-1.5-2.4 hours
Which radiopharmaceutical is made with 99mTc without a reducing agent? - ANS-sulfur
colloid
Which of the following is an example of radiochemical impurity? - ANS-presence of free
99mTc in a preparation of 99mTc sulfur colloid
Which of the following can be said regarding effective half-life? - ANS-it always shorter
than both the physical and the biologic half-life
, The purpose of adding EDTA to sulfur colloid when labeling with 99mTc is: - ANS-to
bind excess Al3+ and to prevent loss of the radiolabel
A diphosphonate kit should generally be used within how many hours after preparation?
- ANS-4 hours
What is the usual particle size of sulfur colloid? - ANS-0.3-1.0 μm
Which radiopharmaceutical,when correctly prepared, will have the smallest particle
size? - ANS-99mTc human serum albumin
The advantages of albumin colloid over sulfur colloid include: - ANS-does not require
boiling
Following injection of 99mTc MAA for a perfusion lung scan, activity is seen in the
kidneys and brain. This is
indicative of: - ANS-right to left cardiac shunt
At 7:00 a.m., a technologist prepares a dose of 99mTcMDP for injection at 10:00 a.m.
that day. The desired
dose is 22 mCi and no precalibration factors are available. The three hour decay factor
for the isotope is 0.707. What amount of activity should the technologist draw up into the
syringe at 7:00 a.m.? - ANS-31.1 mCi
What can be said regarding precalibration factors? - ANS-it is not necessary for problem
solving if the decay factor is available, and it is always >1.0
What method is used to calculate pediatric dose?
a. according to weight
b. Clark's formula
c. according to body surface area
d. using Talbot's nomogram
e. all of the above - ANS-e. all of the above
If the recommended volume for a MAG3 kit ranges from
4-10 ml, and the 99mTc eluate that will be used contains
820 mCi in 10 ml, and 41 mCi will be used,what is the
minimum amount of diluent that should be added? - ANS-3.5 ml
If a 20 mCi dose of 99mTc HDP are needed at 9:00 a.m.,how much activity should the
syringe contain if the technologist prepares it at 7:00 a.m.? - ANS-25.18 mCi
Determine the decay factor for 99mTc
at 7 hours. - ANS-0.445
