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Final Exam Advanced Pathophysiology, Pathophysiology Finals (NEW
UPDATED VERSION) LATEST ACTUAL EXAM QUESTIONS AND CORRECT ANSWERS
(VERIFIED QUESTIONS AND ANSWERS)- GUARANTEED PASS A+ UPDATED
HESI RN Advanced Pathophysiology –
Practice QUESTIONS
1–10: Immunology
1. Which of the following is an example of active immunity?
A. Injection of pooled gamma globulin
B. Breast-feeding
C. Passed from mother to infant via placenta
D. Pneumonia vaccine
Rationale: Active immunity involves stimulating the immune system to produce its own
antibodies, as with vaccines.
2. A patient’s WBC count indicates a shift to the left. What should the nurse assess for?
A. Leukemia
B. Weakness
C. Infection
D. Immunosuppression
Rationale: A left shift indicates increased immature neutrophils (bands), often seen in acute
bacterial infections.
3. Elevated eosinophils in a child with chronic nasal drainage most likely indicate:
A. Bacterial infection
B. Allergies
Rationale: Eosinophils increase in response to allergic reactions.
2026 2027 GRADED A+
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4. Passive immunity occurs when:
A. The body produces antibodies after vaccination
B. Maternal antibodies are transferred to the fetus
C. The body creates memory cells
D. Infection triggers an immune response
5. Anaphylaxis involves which immunoglobulin?
A. IgA
B. IgG
C. IgE
D. IgM
Rationale: IgE binds to allergens and triggers mast cell degranulation.
6. A patient receiving intravenous immunoglobulin (IVIG) is an example of:
A. Active immunity
B. Passive immunity
7. Autoimmune disorders result from:
A. Excess IgA production
B. Immune system attacking self-tissues
C. Bacterial infections only
D. Decreased WBC count
8. Rheumatoid arthritis is primarily a:
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity
D. Type IV hypersensitivity
Rationale: Immune complex deposition in joints leads to inflammation.
9. Lupus (SLE) is characterized by:
A. Autoantibodies causing systemic inflammation
B. T-cell deficiency
2026 2027 GRADED A+
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C. Bacterial overgrowth
D. IgE-mediated reactions
10. Which symptom is common in immunodeficiency?
A. Frequent infections
B. Hypertension
C. Hyperglycemia
D. Constipation
11–20: Hematologic System
11. A patient with iron-deficiency anemia typically presents with:
A. Fatigue
B. Hypertension
C. Hyperactivity
D. Polycythemia
12. Microcytic anemia is often caused by:
A. Vitamin B12 deficiency
B. Iron deficiency
13. Megaloblastic anemia results from:
A. Iron deficiency
B. Vitamin B12 or folate deficiency
14. Sickle cell anemia is characterized by:
A. Abnormal hemoglobin causing vaso-occlusion
B. Platelet deficiency
C. Hypocalcemia
D. Hyperbilirubinemia only
15. Hemophilia A results from deficiency in:
A. Factor VIII
2026 2027 GRADED A+
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B. Factor IX
C. Factor V
D. Fibrinogen
16. Which lab indicates bone marrow response to anemia?
A. Hematocrit
B. Reticulocyte count
17. Polycythemia vera primarily results in:
A. Hypovolemia
B. Increased RBC mass
18. Thrombocytopenia increases risk for:
A. Clots
B. Bleeding
19. A patient with neutropenia is at risk for:
A. Infection
B. Hypertension
C. Hyperglycemia
D. Anemia
20. Vitamin K deficiency primarily affects:
A. RBC production
B. Clotting factor synthesis
21–30: Cardiovascular System
21. Left-sided heart failure commonly presents with:
A. Pulmonary edema
B. Peripheral edema only
C. Jugular vein distention
D. Hepatomegaly only
2026 2027 GRADED A+
Final Exam Advanced Pathophysiology, Pathophysiology Finals (NEW
UPDATED VERSION) LATEST ACTUAL EXAM QUESTIONS AND CORRECT ANSWERS
(VERIFIED QUESTIONS AND ANSWERS)- GUARANTEED PASS A+ UPDATED
HESI RN Advanced Pathophysiology –
Practice QUESTIONS
1–10: Immunology
1. Which of the following is an example of active immunity?
A. Injection of pooled gamma globulin
B. Breast-feeding
C. Passed from mother to infant via placenta
D. Pneumonia vaccine
Rationale: Active immunity involves stimulating the immune system to produce its own
antibodies, as with vaccines.
2. A patient’s WBC count indicates a shift to the left. What should the nurse assess for?
A. Leukemia
B. Weakness
C. Infection
D. Immunosuppression
Rationale: A left shift indicates increased immature neutrophils (bands), often seen in acute
bacterial infections.
3. Elevated eosinophils in a child with chronic nasal drainage most likely indicate:
A. Bacterial infection
B. Allergies
Rationale: Eosinophils increase in response to allergic reactions.
2026 2027 GRADED A+
,2|Page
4. Passive immunity occurs when:
A. The body produces antibodies after vaccination
B. Maternal antibodies are transferred to the fetus
C. The body creates memory cells
D. Infection triggers an immune response
5. Anaphylaxis involves which immunoglobulin?
A. IgA
B. IgG
C. IgE
D. IgM
Rationale: IgE binds to allergens and triggers mast cell degranulation.
6. A patient receiving intravenous immunoglobulin (IVIG) is an example of:
A. Active immunity
B. Passive immunity
7. Autoimmune disorders result from:
A. Excess IgA production
B. Immune system attacking self-tissues
C. Bacterial infections only
D. Decreased WBC count
8. Rheumatoid arthritis is primarily a:
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity
D. Type IV hypersensitivity
Rationale: Immune complex deposition in joints leads to inflammation.
9. Lupus (SLE) is characterized by:
A. Autoantibodies causing systemic inflammation
B. T-cell deficiency
2026 2027 GRADED A+
,3|Page
C. Bacterial overgrowth
D. IgE-mediated reactions
10. Which symptom is common in immunodeficiency?
A. Frequent infections
B. Hypertension
C. Hyperglycemia
D. Constipation
11–20: Hematologic System
11. A patient with iron-deficiency anemia typically presents with:
A. Fatigue
B. Hypertension
C. Hyperactivity
D. Polycythemia
12. Microcytic anemia is often caused by:
A. Vitamin B12 deficiency
B. Iron deficiency
13. Megaloblastic anemia results from:
A. Iron deficiency
B. Vitamin B12 or folate deficiency
14. Sickle cell anemia is characterized by:
A. Abnormal hemoglobin causing vaso-occlusion
B. Platelet deficiency
C. Hypocalcemia
D. Hyperbilirubinemia only
15. Hemophilia A results from deficiency in:
A. Factor VIII
2026 2027 GRADED A+
, 4|Page
B. Factor IX
C. Factor V
D. Fibrinogen
16. Which lab indicates bone marrow response to anemia?
A. Hematocrit
B. Reticulocyte count
17. Polycythemia vera primarily results in:
A. Hypovolemia
B. Increased RBC mass
18. Thrombocytopenia increases risk for:
A. Clots
B. Bleeding
19. A patient with neutropenia is at risk for:
A. Infection
B. Hypertension
C. Hyperglycemia
D. Anemia
20. Vitamin K deficiency primarily affects:
A. RBC production
B. Clotting factor synthesis
21–30: Cardiovascular System
21. Left-sided heart failure commonly presents with:
A. Pulmonary edema
B. Peripheral edema only
C. Jugular vein distention
D. Hepatomegaly only
2026 2027 GRADED A+
