Exam (elaborations)

PCB 3233 IMMUNOLOGY EXAM 4

Rating

Sold

Pages

Grade

A+

Uploaded on

11-01-2026

Written in

2025/2026

PCB 3233 IMMUNOLOGY EXAM 4

Institution

PCB 3233 Immunology

Course

PCB 3233 Immunology

Whoops! We can’t load your doc right now. Try again or contact support.

Report Copyright Violation

Written for

Institution: PCB 3233 Immunology
Course: PCB 3233 Immunology

Document information

Uploaded on: January 11, 2026
Number of pages: 11
Written in: 2025/2026
Type: Exam (elaborations)
Contains: Questions & answers

Subjects

pcb 3233 immunology exam 4

Content preview

PCB 3233 IMMUNOLOGY EXAM 4

Positive0Selection0-0ans✔makes0sure0that0your0T-Cell0recognizes0one0of0your0MHC.

If0it0does0not,0then0apoptosis

Negative0Selection0-
0ans✔Makes0sure0it0does0not0recognize0your0peptide:MHC0too0strongly

Does0gamma:0delta0T-cells0have0to0go0through0positive0selection?0-0ans✔No

What0does0turning0off0RAG01&20do0to0your0gene0rearrangement?0-
0ans✔Preserve0the0current0rearrangement

Primary0Lymphoid0Tissue0-0ans✔bone0marrow0and0thymus

What0does0TH10cells0do?0-0ans✔Activate0macrophages

Thymal0Stromal0Cells0-0ans✔Keeps0BCR0genes0closed0and0opens0TCR0genes

IgM0activates?0-0ans✔complement

Notch-10-0ans✔The0signal0for0survival.0It0drives0the0cell0on0the0T-cell0path0—
0signals0to0open0up0T-cell0rearrangement.

Signaling0rearrangement0keeps0T-cel0on0T-cell0pathway

Where0does0Maturation0and0Positive0Selection0occur?0-0ans✔Cortex0of0the0thymus

Can0negative0selection0also0take0place0in0the0Cortex?0-
0ans✔Yes,0negative0selection0can0take0place0in0the0cortex0at0the0same0time0as0positiv
e0selection

Where0does0negative0selection0take0place?0-0ans✔medulla0of0thymus

Where0are0mature0thymocytes0located?0-0ans✔Medulla

Where0are0immature0thymocytes0located?0-0ans✔Cortex

, What0special0cells0are0in0the0Medulla0-
0ans✔Dendritic0cells,0macrophages,0and0medullary0epithelial0cells

What0special0cells0are0in0the0cortex?0-0ans✔Cortical0epithelial0cells0and0macrophages

Where0can0you0find0AIRE?0-0ans✔in0the0medullary0epithelial0cells

AIRE0-0ans✔Autoimmune0regulator

made0by0medullary0epithelial0cells

Creates0a0couple0hundred0peripheral0peptides0that0can0be0used0to0test0T-
cells0for0negative0selection

DiGeorge's0syndrome0-
0ans✔deletion0in0chromosome0220in0which0thymus0fails0to0develop0and0T-
cells0are0absent

Hassall's0corpuscles0-
0ans✔macrophages0in0both0cortex0and0medulla0remove0the0many0thymocytes0that0fail
0to0mature0properly

Involution0of0the0Thymus0-
0ans✔Progressively0shrinks,0fat0gradually0claiming0areas0once0packed0with0thymocyte
s

-reduces0production0of0new0T-cells

Double0negative0-0ans✔No0CD40and0CD8

Double0Positive0-0ans✔CD40and0CD80are0present

Single0Positive0-0ans✔has0either0CD40or0CD8

CD20and0CD50-
0ans✔perform0adhesion0and0signaling.0They0are0present0during0double0negative0stage

Thymocytes0rearrange0which030genes0at0the0same0time?0-
0ans✔Beta,0gamma,0and0delta

pTalpha0-
0ans✔surrogate0alpha0chain.0signals0cell0to0halt0gamma,0delta,0Beta0chains,0gene0rear
rangement0and0begin0proliferation.

What0do0macrophages0do0in0the0thymus?0-0ans✔continually0remove0dead0cells

$16.49

Get access to the full document:

100% satisfaction guarantee

Immediately available after payment

Both online and in PDF

No strings attached

Get to know the seller

favouredone

4.4

(340)

Get to know the seller

favouredone Havard university

View profile

Sold

328

Member since

2 year

Number of followers

Documents

9010

Last sold

5 days ago

favoredone

Welcome to favoredone ! The place to find the best study materials for various subjects. You can be assured that you will receive only the best which will help you to ace your exams. All the materials posted are A+ Graded. Please rate and write a review after using my materials. Your reviews will motivate me to add more materials. Thank you very much!

4.4

340 reviews

222

Why students choose Stuvia

Created by fellow students, verified by reviews

Quality you can trust: written by students who passed their tests and reviewed by others who've used these notes.

Didn't get what you expected? Choose another document

No worries! You can instantly pick a different document that better fits what you're looking for.

Pay as you like, start learning right away

No subscription, no commitments. Pay the way you're used to via credit card and download your PDF document instantly.

“Bought, downloaded, and aced it. It really can be that simple.”

Alisha Student

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller favouredone. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $16.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews) 51249 documents were sold in the last 30 days Founded in 2010, the go-to place to buy study notes for 16 years now

PCB 3233 IMMUNOLOGY EXAM 4

Written for

Document information

Subjects

Content preview

Get to know the seller

Recently viewed by you

Why students choose Stuvia

Created by fellow students, verified by reviews

Didn't get what you expected? Choose another document

Pay as you like, start learning right away

Frequently asked questions

What do I get when I buy this document?

Satisfaction guarantee: how does it work?

Who am I buying these notes from?

Will I be stuck with a subscription?

Can Stuvia be trusted?