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PCB 3233 Immunology Exam 4 Questions and Answers 2026/2027 |Already Graded A+| Verified and Updated

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PCB 3233 Immunology Exam 4 Questions and Answers 2026/2027 |Already Graded A+| Verified and Updated

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PCB 3233 Immunology Exam 4
Questions and Answers 2026/2027
|Already Graded A+| Verified and
Updated

If there is no B7 then what occurs? - correct answer -anergy




Adjuvant - correct answer -a substance that enhances the body's
immune response to an antigen


ex. whole bacterium used to induce co-stimulatory activity in P-APC's




True or false? AIRE is used in negative and positive selection? - correct
answer -False, only in negative selection




True or false? Central tolerance is referred to both positive and negative
selection? - correct answer -False, negative selection

,What causes the differentiation into 5 CD4 T-cells? - correct answer -
Cytokine environment causes differentiation. Which means the
cytokines secreted and the transcription factors




TGF-B - correct answer -immunosuppressive cytokine




Polarization - correct answer -Bias of either TH1 or TH2




TH2 - correct answer -Humoral response


Transcription factor: GATA-3


Induced by: IL-4


Secretes: IL-4 & IL-5


Activates B-cells to secrete IgE against parasitic infections

,Lepromatous Leprosy (Most well known)




TH1 - correct answer -Cell Mediated


Induced by: IL-12 & IFN-y


Transcription factor: T-bet


Secretes IL-12, IFN-y, GM-CSF, & TNF-a


Activates Macrophages


Tubercloid Leprosy




Treg - correct answer -Induced by: TGF-B


Transcription Factor: FoxP3

, Secretes: TGF-B & IL-10


Suppresses immune response




TH17 - correct answer -Transcription Factor: RORyT


Secretes: IL-17, IL-6


Recruits Neutrophils




TFH - correct answer --transcription factor: Bcl6


-Function: activates B cells into isotyped switched B cells




Which T-cells are the hardest to activate? - correct answer -CD8

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