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ADVANCED PATHOPHYSIOLOGY MIDTERM QUESTIONS AND CORRECT ANSWERS 2026

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A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance? -correct answers Answer: Anaerobic glycolysis What causes the rapid change in the resting membrane potential that initiates an action potential? -correct answers Answer: Sodium gates open, and sodium rushes into the cell, changing the membrane potential from negative to positive. A 12-year-old male is diagnosed with Klinefelter syndrome. His karyotype would reveal which of the following? -correct answers Answer: XXY A nurse is reviewing the pedigree chart. When checking for a proband, what is the nurse looking for? -correct answers Answer: The person who is first diagnosed with a genetic disease

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Advanced Pathophysiology 6501
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Advanced Pathophysiology 6501

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A runner has depleted all the oxygen available for muscle energy. Which of the following will
facilitate his con nued muscle performance? -correct answers Answer: Anaerobic glycolysis



What causes the rapid change in the res ng membrane poten al that ini ates an ac on
poten al? -correct answers Answer: Sodium gates open, and sodium rushes into the cell,
changing the membrane poten al from nega ve to posi ve.



A 12-year-old male is diagnosed with Klinefelter syndrome. His karyotype would reveal which of
the following? -correct answers Answer: XXY



A nurse is reviewing the pedigree chart. When checking for a proband, what is the nurse looking
for? -correct answers Answer: The person who is first diagnosed with a gene c disease



An aide asks the nurse why people who have neurofibromatosis will show varying degrees of
the disease. Which gene c principle should the nurse explain to the aide? -correct answers
Answer: Expressivity



In teaching a pa ent with cirrhosis, which informa on should the nurse include regarding
cholesterol? -correct answers Answer: Cholesterol decreases the membrane fluidity of the
erythrocyte, which reduces its ability to carry oxygen.



When a pa ent asks what causes cys c fibrosis, how should the nurse respond? Cys c fibrosis is
caused by an _____ gene -correct answers Answer: Autosomal recessive

, How are potassium and sodium transported across plasma membranes? -correct answers
Answer: By adenosine triphosphate enzyme (ATPase)



The nurse would be correct in iden fying the predominant extracellular ca on as: -correct
answers Answer: Sodium



The early dila on (swelling) of the cell's endoplasmic re culum results in: -correct answers
Answer: Reduced protein synthesis



What principle should the nurse remember when trying to dis nguish aging from diseases? -
correct answers Answer: It is difficult to tell the difference because both processes are believed
to result from cell injury.



What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent
homologous X chromosome with only a single X chromosome present? Her features include a
short stature, widely spaced nipples, reduced carrying angle at the elbow, and sparse body hair.
-correct answers Answer: Turner syndrome



A eukaryo c cell is undergoing DNA replica on. In which region of the cell would most of the
gene c informa on be contained? -correct answers Answer: Nucleolus



The nurse is teaching staff about the most common cause of Down syndrome. What is the nurse
describing? -correct answers Answer: Maternal nondisjunc on



A 50-year-old male was recently diagnosed with Hun ngton disease. Transmission of this
disease is associated with: -correct answers Answer: Delayed age of onset



A pa ent wants to know the risk factors for Down syndrome. What is the nurse's best response?
-correct answers Answer: Pregnancy in women over age 35

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Advanced Pathophysiology 6501
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Advanced Pathophysiology 6501

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