Psychopharmacology 2025: Drugs, the Brain, and Behavior — Test Bank & Study Guide

PsychopharmacologykDrugskthekBrainkAndkBehaviork3rdkEditionkmeyerkNursing
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,PsychopharmacologykDrugskthekBrainkAndkBehaviork3rdkEditionkmeyerkNursing
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Psychopharmacology,kThirdkEdition
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Chapterk1:kPrincipleskofkPharmacology

MultiplekChoice

1. k
refer(s)ktokspecifickmolecularkchangeskthatkoccurkwhenkakdrugkbindsktokakparticularkt
argetksitekorkreceptor,kwhile
arekthekresultingkwidespreadkalterationskinkfunction.
a. Drugkaction;ktherapeutickeffects
b. Sidekeffects;kdrugkeffects
c. Therapeutickeffects;ksidekeffects
d. Drugkaction;kdrugkeffects
Answer:kd
TextbookkReference:kPharmacology:kThekSciencekofkDrugkAction

2. Afterkdrugkadministrationkhaskoccurred,kthekamountkofkdrugkinkthekbloodkthatkiskfreek
tokbindkatkspecificktargetksiteskiskreferredktokas
a. thektherapeutickdose.
b. first-passkeffects.
c. bioavailability.
d. ED50.
Answer:kc
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

3. Thekspecifickmolecularkchangeskthatkoccurkwhenkakdrugkbindsktokakparticularktargetksi
tekorkreceptorkarekreferredktokas
a. drugkeffects.
b. drugkaction.
c. sidekeffects.
d. placebokeffects.
Answer:kb
TextbookkReference:kPharmacology:kThekSciencekofkDrugkAction

4. Whichkofkthekfollowingkisknotkakpossiblekexplanationkforkplacebokeffects?
a. Pavloviankconditioning
b. Genetickvariation
c. Drugkcompetition
d. Expectationkofkoutcome
Answer:kc
TextbookkReference:kPharmacology:kThekSciencekofkDrugkAction

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5. The administrationkofkoxytocinkhaskbeenkproposedkaskaktreatmentkforkautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:kc
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

6. Whichkfactorkdoesknotkaffectkthekpharmacokineticskofkakdrug?
a. Routekofkadministration
b. Lipidksolubility
c. Depotkbinding
d. Drugkaction
Answer:kd
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

7. First-passkmetabolismkoccurskwhenkdrugskarektaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:ka
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

8. Thekareakpostremakiskonekareakinkthekbrainkwherekthe isknotkcomplete.
a. cerebrospinalkfluid
b. blood–brainkbarrier
c. choroidkplexus
d. phospholipidkmembrane
Answer:kb
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

9. First-passkmetabolismkoccurskwithkorallykadministeredkdrugskbecause
a. theirkabsorptionkiskslowedkbykfood.
b. drugskabsorbedkintokthekbloodstreamkfromkthekstomachkgoktokthekliverkonkthekwayk
tokgeneralkcirculation.
c. drugskmustkfirstksurvivekthekacidickenvironmentkofkthekstomach.
d. salivarykenzymeskinkthekmouthkbeginkthekprocesskofkmetabolism.
Answer:kb
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

10. Toxicksubstanceskinkthekbloodktriggerkakvomitingkresponsekbykactivatingkthe
a. blood–brainkbarrier.
b. choroidkplexus.
c. areakpostrema.
d. mediankeminence.



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Answer:kc
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

11. Drugskadministeredk_ havekthekmostkrapidkonsetkofkaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:kd
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

12. Ionizationkofkakdrugkdependskonkthe ofktheksolutionkandkthe
ofkthekdrug.
a. pH;kpKa
b. pKa;kpH
c. concentration;klipidksolubility
d. pH;kconcentration
Answer:ka
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

13. Thekabsorptionkofkakdrugkdependskonkallkofkthekfollowingkexcept
a. lipidksolubility.
b. ionization.
c. bodyktemperature.
d. thekconcentrationkofkthekdrug.
Answer:kc
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

14. Drugskthatkare shouldkbekavoidedkbykwomenkofkchildbearingkage.
a. teratogenic
b. ablektokcrosskthekplacentalkbarrier
c. psychoactive
d. highlyklipid-soluble
Answer:ka
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

15. Agentskthatkinducekdevelopmentalkabnormalitieskinkakfetuskarekknownkas
a. psychoactivekdrugs.
b. illicitkdrugs.
c. teratogens.
d. placentalkdrugs.
Answer:kc
TextbookkReference:kPharmacokinetickFactorskDeterminingkDrugkAction

16. Depotkbindingkisksaidktokoccurkwhenkdrugs
a. bindktoktheirktargetksites.



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