Psychopharmacology 2025: Drugs, the Brain, and Behavior – Test Bank & Study Guide

PsychopharmacologyjDrugsjthejBrainjAndjBehaviorj3rdjEditionjmeyerjNursingjTe
stjBank

,PsychopharmacologyjDrugsjthejBrainjAndjBehaviorj3rdjEditionjmeyerjNursingjTe
stjBank




TestjBank
tojaccompany
Psychopharmacology,jThirdjEdition
Meyerj•jQuenzer


Chapterj1:jPrinciplesjofjPharmacology

MultiplejChoice

1. j
refer(s)jtojspecificjmolecularjchangesjthatjoccurjwhenjajdrugjbindsjtojajparticularjtarge
tjsitejorjreceptor,jwhile
arejthejresultingjwidespreadjalterationsjinjfunction.
a. Drugjaction;jtherapeuticjeffects
b. Sidejeffects;jdrugjeffects
c. Therapeuticjeffects;jsidejeffects
d. Drugjaction;jdrugjeffects
Answer:jd
TextbookjReference:jPharmacology:jThejSciencejofjDrugjAction

2. Afterjdrugjadministrationjhasjoccurred,jthejamountjofjdrugjinjthejbloodjthatjisjfreejtojbin
djatjspecificjtargetjsitesjisjreferredjtojas
a. thejtherapeuticjdose.
b. first-passjeffects.
c. bioavailability.
d. ED50.
Answer:jc
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

3. Thejspecificjmolecularjchangesjthatjoccurjwhenjajdrugjbindsjtojajparticularjtargetjsitejorj
receptorjarejreferredjtojas
a. drugjeffects.
b. drugjaction.
c. sidejeffects.
d. placebojeffects.
Answer:jb
TextbookjReference:jPharmacology:jThejSciencejofjDrugjAction

4. Whichjofjthejfollowingjisjnotjajpossiblejexplanationjforjplacebojeffects?
a. Pavlovianjconditioning
b. Geneticjvariation
c. Drugjcompetition
d. Expectationjofjoutcome
Answer:jc
TextbookjReference:jPharmacology:jThejSciencejofjDrugjAction

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5. The administrationjofjoxytocinjhasjbeenjproposedjasjajtreatmentjforjautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:jc
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

6. Whichjfactorjdoesjnotjaffectjthejpharmacokineticsjofjajdrug?
a. Routejofjadministration
b. Lipidjsolubility
c. Depotjbinding
d. Drugjaction
Answer:jd
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

7. First-passjmetabolismjoccursjwhenjdrugsjarejtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:ja
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

8. Thejareajpostremajisjonejareajinjthejbrainjwherejthe isjnotjcomplete.
a. cerebrospinaljfluid
b. blood–brainjbarrier
c. choroidjplexus
d. phospholipidjmembrane
Answer:jb
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

9. First-passjmetabolismjoccursjwithjorallyjadministeredjdrugsjbecause
a. theirjabsorptionjisjslowedjbyjfood.
b. drugsjabsorbedjintojthejbloodstreamjfromjthejstomachjgojtojthejliverjonjthejwayjtojge
neraljcirculation.
c. drugsjmustjfirstjsurvivejthejacidicjenvironmentjofjthejstomach.
d. salivaryjenzymesjinjthejmouthjbeginjthejprocessjofjmetabolism.
Answer:jb
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

10. Toxicjsubstancesjinjthejbloodjtriggerjajvomitingjresponsejbyjactivatingjthe
a. blood–brainjbarrier.
b. choroidjplexus.
c. areajpostrema.
d. medianjeminence.



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, PsychopharmacologyjDrugsjthejBrainjAndjBehaviorj3rdjEditionjmeyerjNursingjTe
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Answer:jc
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

11. Drugsjadministeredj_ havejthejmostjrapidjonsetjofjaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:jd
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

12. Ionizationjofjajdrugjdependsjonjthe ofjthejsolutionjandjthe
ofjthejdrug.
a. pH;jpKa
b. pKa;jpH
c. concentration;jlipidjsolubility
d. pH;jconcentration
Answer:ja
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

13. Thejabsorptionjofjajdrugjdependsjonjalljofjthejfollowingjexcept
a. lipidjsolubility.
b. ionization.
c. bodyjtemperature.
d. thejconcentrationjofjthejdrug.
Answer:jc
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

14. Drugsjthatjare shouldjbejavoidedjbyjwomenjofjchildbearingjage.
a. teratogenic
b. ablejtojcrossjthejplacentaljbarrier
c. psychoactive
d. highlyjlipid-soluble
Answer:ja
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

15. Agentsjthatjinducejdevelopmentaljabnormalitiesjinjajfetusjarejknownjas
a. psychoactivejdrugs.
b. illicitjdrugs.
c. teratogens.
d. placentaljdrugs.
Answer:jc
TextbookjReference:jPharmacokineticjFactorsjDeterminingjDrugjAction

16. Depotjbindingjisjsaidjtojoccurjwhenjdrugs
a. bindjtojtheirjtargetjsites.



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