GEORGETTE ACTUAL UPDATED QUESTIONS AND ANSWERS
GRADED A+
✔✔cyclothymic disorder - ✔✔at least ****2 years
subsyndromal mood elevation and depression ...not full blow manic or MDD
✔✔black box warning carbemazepine tegretol - ✔✔agranulocytosis and aplastic anemia
✔✔Which med can cause hyperammonemia? increased LFTs? - ✔✔valproate
depakote.
blackbox warning hepatotoxicity and pancreatitis
✔✔Wt gain propensity greatest to least for bipolar meds - ✔✔valproate depakote LOTS
OF WT GAIN
lithium
lamictal- least amount
✔✔Meds approved for bipolar depression? - ✔✔olazapine and fluoxetine
quetiapine (by itself)
latuda...used alone OR in combo w/ lithium or valproate (depakote)
lamictal (bipolar I disorder maintanence only)
✔✔Valproic Depakote - ✔✔more effective than lithium for rapid cycling/mixed episodes
✔✔dysthymia - ✔✔present for 2 years chronic depression that doesn't meet full MDD
criteria
✔✔What meds are FDA approved for bipolar mania? - ✔✔lithium
olanzapine
chlorpromazine
Lamotrigine isn't
✔✔BP disorder prevalance - ✔✔Bipolar I equal in men and women
Bipolar II more common in women
men more manic, women more commonly rapid cycling/mixed states, depressive,
comorbid eating disorders
✔✔Lamotrigine - ✔✔Valporate or Depakote is an inhibitor- so lowers lamictal doses, so
need to slow titration of lamictal in half.
, Carbamazepine (tegretol) is an inducer, so are birht control, and rifampin...so lowers the
dose of lamictal
✔✔3rd trimester fetal exposure to SSRIs? - ✔✔seizures
✔✔What is true about lithium and pregnancy? - ✔✔if stopped..should be restarted after
delivery at preconception dose
✔✔Which SSRI increases fetal cardiac abnormalities? - ✔✔paroxetine paxil
✔✔What is true about ECT and pregnancy? - ✔✔propofol and methohexital sodium are
both short acting and not teratogenic
✔✔Which PD is often confused w/ schizophrenia? - ✔✔schizoid PD
✔✔Enuresis is most commonly comorbid with? - ✔✔ADHD
✔✔Autism spectrum percent of population in US? (Prevalence) - ✔✔1%
Incidence 2-5:100,000
Male to female 4:1
Sx onset before age 3
10% have genetics Down syndrome or fragile X
More common if fam hx of pervasive developmental disorders
✔✔Tryptophan - ✔✔Avoid w/ MAOIs and SSRIs risk for serotonin syndrome
✔✔Mood disorder atypical fx - ✔✔Wt gain, excessive sleep, sluggish, or paralyzed,
sensitive to rejection
✔✔Mood w/ melancholic fx - ✔✔Feel worse in morning than afternoon, decreased
appetite, wt loss, agitation, excessive guilt, trouble making decisions
✔✔W/ catatonic features - ✔✔Muscle or motor hyperactivity OR inactivity
✔✔fish oil interacts with - ✔✔NSAIDS, warfarin, ASA, garlic and ginkgo
✔✔Valarian Root - ✔✔Psychoactive herb for insomnia
Not anxiety
GRADED A+
✔✔cyclothymic disorder - ✔✔at least ****2 years
subsyndromal mood elevation and depression ...not full blow manic or MDD
✔✔black box warning carbemazepine tegretol - ✔✔agranulocytosis and aplastic anemia
✔✔Which med can cause hyperammonemia? increased LFTs? - ✔✔valproate
depakote.
blackbox warning hepatotoxicity and pancreatitis
✔✔Wt gain propensity greatest to least for bipolar meds - ✔✔valproate depakote LOTS
OF WT GAIN
lithium
lamictal- least amount
✔✔Meds approved for bipolar depression? - ✔✔olazapine and fluoxetine
quetiapine (by itself)
latuda...used alone OR in combo w/ lithium or valproate (depakote)
lamictal (bipolar I disorder maintanence only)
✔✔Valproic Depakote - ✔✔more effective than lithium for rapid cycling/mixed episodes
✔✔dysthymia - ✔✔present for 2 years chronic depression that doesn't meet full MDD
criteria
✔✔What meds are FDA approved for bipolar mania? - ✔✔lithium
olanzapine
chlorpromazine
Lamotrigine isn't
✔✔BP disorder prevalance - ✔✔Bipolar I equal in men and women
Bipolar II more common in women
men more manic, women more commonly rapid cycling/mixed states, depressive,
comorbid eating disorders
✔✔Lamotrigine - ✔✔Valporate or Depakote is an inhibitor- so lowers lamictal doses, so
need to slow titration of lamictal in half.
, Carbamazepine (tegretol) is an inducer, so are birht control, and rifampin...so lowers the
dose of lamictal
✔✔3rd trimester fetal exposure to SSRIs? - ✔✔seizures
✔✔What is true about lithium and pregnancy? - ✔✔if stopped..should be restarted after
delivery at preconception dose
✔✔Which SSRI increases fetal cardiac abnormalities? - ✔✔paroxetine paxil
✔✔What is true about ECT and pregnancy? - ✔✔propofol and methohexital sodium are
both short acting and not teratogenic
✔✔Which PD is often confused w/ schizophrenia? - ✔✔schizoid PD
✔✔Enuresis is most commonly comorbid with? - ✔✔ADHD
✔✔Autism spectrum percent of population in US? (Prevalence) - ✔✔1%
Incidence 2-5:100,000
Male to female 4:1
Sx onset before age 3
10% have genetics Down syndrome or fragile X
More common if fam hx of pervasive developmental disorders
✔✔Tryptophan - ✔✔Avoid w/ MAOIs and SSRIs risk for serotonin syndrome
✔✔Mood disorder atypical fx - ✔✔Wt gain, excessive sleep, sluggish, or paralyzed,
sensitive to rejection
✔✔Mood w/ melancholic fx - ✔✔Feel worse in morning than afternoon, decreased
appetite, wt loss, agitation, excessive guilt, trouble making decisions
✔✔W/ catatonic features - ✔✔Muscle or motor hyperactivity OR inactivity
✔✔fish oil interacts with - ✔✔NSAIDS, warfarin, ASA, garlic and ginkgo
✔✔Valarian Root - ✔✔Psychoactive herb for insomnia
Not anxiety
