BIOL351 / BIOL 351 Module 7
(Latest Update )
Pharmacology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Gastroenterology
Question:
What is the mechanism of action for serotonin blockers in nausea treatment?
Answer:
They block serotonin receptors in the GI tract, CTZ, and vomiting center
subtype involved in N/V is the 5-hydroxytryptamine receptor
Question:
adverse events for serotonin blockers
Answer:
heartache, bronchospasm, diarrhea
,Question:
drug interaction for serotonin blockers
Answer:
no major drug interactions
Question:
select serotonin blocker medications
Answer:
ondansetron, granisetron, dolasetron, and palonosetron
Question:
list the 2 most common causes of peptic ulcers
Answer:
H. pylori and long term use of NSAIDs
Question:
describe the pathophysiology of GERD
Answer:
involves the lower esophageal sphincter (LES) loosening so gastric acid is able
to go back up (reflux) into the esophagus
,Question:
what are the components of the quadruple therapy when referring to H. pylori
treatment regimen
Answer:
2 antibiotics, Peptic-Bismol (bismuth salt), and a PPI
Question:
explain the mechanism of acid of the acid controlling drugs H2
Answer:
work by competitively inhibit the interaction of histamine with H2 receptors
within the GI mucosae
this blockade significantly reduces the secretion of acid and pepsin from the
stomach
Question:
explain the mechanism of action of the acid controlling drugs, PPIs
Answer:
the exchange of hydrogen and potassium via the ATPPase exchange is
essential to the production of HCL
PPIs work by inhibiting this exchange therefore preventing the formation of
acid
, Question:
list the various classes of antidiarrheals
Answer:
(1) adsorbents, (2) antimotility (anticholinergic and opiates), and (3)
probiotics.
Question:
Describe the mechanism of action of the two types of anti-motility
antidiarrheals
Answer:
anticholinergic: works by slowing peristalsis by reducing the contractions and
smooth muscle tone in the GI tract. they also work by drying gastric secretion
opiates: works by acting on smooth muscle cells in the GI tract inhibiting
motility and excessive GI propulsion. this results in a decrease in the number
of stool and their water content
Question:
list the medications used to treat constipation
Answer:
laxatives- bulk, emollient, hyperosmotic, saline, stimulant
(Latest Update )
Pharmacology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Gastroenterology
Question:
What is the mechanism of action for serotonin blockers in nausea treatment?
Answer:
They block serotonin receptors in the GI tract, CTZ, and vomiting center
subtype involved in N/V is the 5-hydroxytryptamine receptor
Question:
adverse events for serotonin blockers
Answer:
heartache, bronchospasm, diarrhea
,Question:
drug interaction for serotonin blockers
Answer:
no major drug interactions
Question:
select serotonin blocker medications
Answer:
ondansetron, granisetron, dolasetron, and palonosetron
Question:
list the 2 most common causes of peptic ulcers
Answer:
H. pylori and long term use of NSAIDs
Question:
describe the pathophysiology of GERD
Answer:
involves the lower esophageal sphincter (LES) loosening so gastric acid is able
to go back up (reflux) into the esophagus
,Question:
what are the components of the quadruple therapy when referring to H. pylori
treatment regimen
Answer:
2 antibiotics, Peptic-Bismol (bismuth salt), and a PPI
Question:
explain the mechanism of acid of the acid controlling drugs H2
Answer:
work by competitively inhibit the interaction of histamine with H2 receptors
within the GI mucosae
this blockade significantly reduces the secretion of acid and pepsin from the
stomach
Question:
explain the mechanism of action of the acid controlling drugs, PPIs
Answer:
the exchange of hydrogen and potassium via the ATPPase exchange is
essential to the production of HCL
PPIs work by inhibiting this exchange therefore preventing the formation of
acid
, Question:
list the various classes of antidiarrheals
Answer:
(1) adsorbents, (2) antimotility (anticholinergic and opiates), and (3)
probiotics.
Question:
Describe the mechanism of action of the two types of anti-motility
antidiarrheals
Answer:
anticholinergic: works by slowing peristalsis by reducing the contractions and
smooth muscle tone in the GI tract. they also work by drying gastric secretion
opiates: works by acting on smooth muscle cells in the GI tract inhibiting
motility and excessive GI propulsion. this results in a decrease in the number
of stool and their water content
Question:
list the medications used to treat constipation
Answer:
laxatives- bulk, emollient, hyperosmotic, saline, stimulant
