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Pharmacology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Pharmacology of infectious disease
Question:
nephrotoxicity
Answer:
kidney damage
Question:
ototoxicity
Answer:
ear damage
,Question:
aminoglycosides pregnancy category
Answer:
D- have been shown to cause hearing loss and deafness in the fetus
Question:
drug interaction- aminoglycosides
Answer:
-general anesthesia by producing excessive muscular blockage (risk of leading
to respiratory arrest or paralysis of the diaphragm)
-ototoxic effect can be increase when taken with furosemide
-nephrotoxic effect is increased when taken with cephalosporins
Question:
select aminoglycoside antibiotics
Answer:
amikacon (amikin); gentamicin (Garamycin); tobramycin (Nebcin)
,Question:
amikacin (Amikin) usage
Answer:
reserved for treatment of serious gram-negative infections, especially with
bacteria resistant to tobramycin or gentamicin
Question:
gentamicin (Garamycin) usage
Answer:
reserved for the treatment of serious gram-negative infections; produce a
significant incidence of ototoxicity
Question:
tobramycin (Nebcin) usage
Answer:
reserved for the treatment of serious gram-negative infections, particularly
pseudomonas aeruginosa
, Question:
advantage over other broad spectrum antibiotics is that they have good oral
absorption
Answer:
fluroquinolones
Question:
mechanism of action- fluroquinolones
Answer:
bactericidal; inhibit bacterial enzymes necessary for DNA synthesis and
bacterial replication
Question:
spectrum- fluoroquinolones
Answer:
gram-negative and some gram-positive (not MRSA)
-moxifloxacin has the most gram-positive