NURS 5357 NEUROBIOLOGY COMPREHENSIVE EXAM
QUESTIONS AND SOLUTIONS RATED A+
✔✔ What brain area is associated with working memory in ADHD? - ✔✔Prefrontal
Cortex
✔✔Which brain area is linked to temporal processing in ADHD? - ✔✔Cerebellum
✔✔What is the role of the nucleus accumbens in ADHD? - ✔✔It is associated with delay
of gratification.
✔✔What compensatory change occurs in the parietal cortex of children who outgrew
ADHD? - ✔✔Normalization of gray matter thickness.
✔✔How do ADHD symptoms change from childhood to adulthood? - ✔✔Symptoms
may diminish or change in presentation as individuals mature.
✔✔What impact does trauma have on the prefrontal cortex? - ✔✔It impairs working
memory.
✔✔What is the effect of stimulant medication on dopamine in ADHD? - ✔✔It increases
dopamine release at the nucleus accumbens, improving impulse control.
✔✔What happens to the total brain volume in children with ADHD? - ✔✔It is
approximately 5% smaller across all cerebral lobes.
✔✔What is the primary pathological finding in Alzheimer's dementia? - ✔✔Cortical
atrophy and neuronal loss.
✔✔What are amyloid plaques and their significance in Alzheimer's? - ✔✔They are
extracellular deposits of beta-amyloid protein that contribute to neuronal damage.
✔✔What causes neurofibrillary tangles in Alzheimer's disease? -
✔✔Hyperphosphorylation of tau proteins leads to their detachment from microtubules,
forming tangles.
✔✔What is the hallmark sign of Alzheimer's disease? - ✔✔Shrinkage of cortical tissue
due to neuronal cell death.
✔✔How does drug abuse affect the nucleus accumbens? - ✔✔Chronic cocaine use
downregulates dopamine receptors in the nucleus accumbens.
✔✔What is the role of the anterior cingulate cortex in ADHD? - ✔✔It is involved in
emotional regulation and impulse control.
QUESTIONS AND SOLUTIONS RATED A+
✔✔ What brain area is associated with working memory in ADHD? - ✔✔Prefrontal
Cortex
✔✔Which brain area is linked to temporal processing in ADHD? - ✔✔Cerebellum
✔✔What is the role of the nucleus accumbens in ADHD? - ✔✔It is associated with delay
of gratification.
✔✔What compensatory change occurs in the parietal cortex of children who outgrew
ADHD? - ✔✔Normalization of gray matter thickness.
✔✔How do ADHD symptoms change from childhood to adulthood? - ✔✔Symptoms
may diminish or change in presentation as individuals mature.
✔✔What impact does trauma have on the prefrontal cortex? - ✔✔It impairs working
memory.
✔✔What is the effect of stimulant medication on dopamine in ADHD? - ✔✔It increases
dopamine release at the nucleus accumbens, improving impulse control.
✔✔What happens to the total brain volume in children with ADHD? - ✔✔It is
approximately 5% smaller across all cerebral lobes.
✔✔What is the primary pathological finding in Alzheimer's dementia? - ✔✔Cortical
atrophy and neuronal loss.
✔✔What are amyloid plaques and their significance in Alzheimer's? - ✔✔They are
extracellular deposits of beta-amyloid protein that contribute to neuronal damage.
✔✔What causes neurofibrillary tangles in Alzheimer's disease? -
✔✔Hyperphosphorylation of tau proteins leads to their detachment from microtubules,
forming tangles.
✔✔What is the hallmark sign of Alzheimer's disease? - ✔✔Shrinkage of cortical tissue
due to neuronal cell death.
✔✔How does drug abuse affect the nucleus accumbens? - ✔✔Chronic cocaine use
downregulates dopamine receptors in the nucleus accumbens.
✔✔What is the role of the anterior cingulate cortex in ADHD? - ✔✔It is involved in
emotional regulation and impulse control.
