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CDE Exam Study Guide Questions and Answers Updated 2026

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CDE Exam Study Guide Questions and Answers Updated 2026

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CDE Exam Study Guide Questions
and Answers Updated 2026
PramlintideB-
BAnswer(Symlin)B1)BslowsBtheBrateBofBdigestionBfromBstomachBtoBintestinesB2)BlowersBtheBa
mountBofBglucoseBproducedBbyBtheBliverB3)BtriggersBtheBfeelingBofBfullnessBafterBeating.



PramlintideBDosingB-
BAnswerReduceBmealtimeBinsulinBbyB50%,BthenBinitiateBatB15mcgBimmediatelyBpriorBtoBmeal
s.BThenBincreaseBtoB30,B45,BorB60mcgBwhenBnoBclinicallyBsignificantBnauseaBhasBoccurredBfo
rBatBleastB3Bdays.



PramlintideBContraindications/ConsiderationsB-BAnswerCan'tBbeBmixedBwithBinsulins



MayBdelayBabsorptionBofBco-
administeredBoralBmedsB(takeBthoseB1hrBpriorBorB2hrBafterBSymlin)



NotBusedBforBptsBonBanticholinergicsBorBothersBthatBwillBslowBgastricBemptying



CannotBbeBusedBinBptsBwithBconfirmedBgastroparesis



IncreasedBriskBofBhypoglycemiaBwithBACE-I,BMAOI,BFluoxetine,BandBsulfaBabx.



TargetBCholesterolBLevelsBforBHigh-RiskBpatientsB-BAnswerLDL:B100-129

Total:B200-239

HDL:B>40



WhatBareBHGM-CoABReductaseBInhibitors?B-BAnswerStatins



FuelBHomeostasisBStageB1B-BAnswerFedBstateB-B0-3.8hr



InsulinBinhibitsBbreakdownBofBglycogenBandBTGBreservoirs



FuelBHomeostasisBStageB2B-BAnswerPost-AbsorptiveBStateB-B4-15.9hr

, InsulinBlevelsBdecrease,BglucagonBlevelsBrise



FuelBHomeostasisBStageB3B-BAnswerEarlyBStarvationBStateB-B16-47.9hr



LactateBmakesBupBhalfBofBgluconeogenicBsubstrate.BInsulinBisBsuppressedBandBcounter-
regulatoryBhormonesBareBstimulated.



FuelBHomeostasisBStageB4B-BAnswerPreliminaryBProlongedBStarvationBStateB(48hrB-B23.9Bdays)



BGBcomesBfromBhepaticBandBrenalBgluconeogenesis.BInsulinBisBmarkedlyBsuppressedBbyB60hr,
BandBglucagon,Bcortisol,BgrowthBhormone,BandBepinephrineBareBstimulated.



FuelBHomeostasisBStageB5B-BAnswerSecondaryBProlongedBStarvationBStateB(24-40Bdays)



BGBoriginatesBfromBhepatic/renalBgluconeogenesisBstill,BbutBrateBofBglucoseBuseBbyBbrainBdim
inishesBandBrateBofBhepaticBgluconeogenesisBslows.



CentralBObesityBWaistBSizeB-BAnswerMen:B>40in

Women:B>30in



MetabolicBActivityBofBAbdominalBFatB-
BAnswerMoreBcapillaries,BinfluxBofBFFA.BInBliver,BFFA'sBcauseBinsulinBresistance,BandBFFABcanB
beBusedBasBfuel,BthusBraisingBBG



BMIBRangeBClassificationsB-BAnswerUnder:B<18.5

Normal:B18.5-24.9

Over:B25-29.9

Obese:B>30



GlycemicBControlBTestsB-BAnswerFructosamine:B2-3Bweeks



GlycatedBAlbumin:B2-3Bweeks

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