MN 553 MAIN EXAMINATION SET QUESTIONS AND
SOLUTIONS RATED A+
✔✔The next step in treatment when a patient has been on proton pump inhibitors twice
daily for 12 weeks and not improving is:
1. Add a prokinetic (metoclopramide)
2. Referral for endoscopy
3. Switch to another proton pump inhibitor
4. Add a cytoprotective drug - ✔✔2. Referral for endoscopy
✔✔Infants with reflux are initially treated with:
1. Histamine2 receptor antagonist (ranitidine)
2. Proton pump inhibitor (omeprazole)
3. Anti-reflux maneuvers (elevate the head of the bed)
4. Prokinetic (metoclopramide) - ✔✔3. Anti-reflux maneuvers (elevate the head of the
bed)
✔✔Long-term use of proton pump inhibitors may lead to:
1. Hip fractures in at-risk persons
2. Vitamin B6 deficiency
3. Liver cancer
4. All of the above - ✔✔1. Hip fractures in at-risk persons
✔✔An acceptable first-line treatment for peptic ulcer disease with positive H. pylori test
is:
1. Histamine2 receptor antagonists for 4 to 8 weeks
2. Proton pump inhibitor bid for 12 weeks until healing is complete
3. Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
4. Proton pump inhibitor bid and levofloxacin for 14 days - ✔✔3. Proton pump inhibitor
bid plus clarithromycin plus amoxicillin for 14 days
✔✔Treatment failure in patients with peptic ulcer disease associated with H. pylori may
be because of:
1. Antimicrobial resistance
2. An ineffective antacid
3. Overuse of proton pump inhibitors
4. All of the above - ✔✔1. Antimicrobial resistance
✔✔If a patient with H. pylori-positive peptic ulcer disease fails first-line therapy, the
second-line treatment is:
, 1. Proton pump inhibitor bid plus metronidazole plus tetracycline plus bismuth
subsalicylate for 14 days
2. Test H. pylori for resistance to common treatment regimens
3. Proton pump inhibitor plus clarithromycin plus amoxicillin for 14 days
4. Proton pump inhibitor and levofloxacin for 14 days - ✔✔1. Proton pump inhibitor bid
plus metronidazole plus tetracycline plus bismuth subsalicylate for 14 days
✔✔After H. pylori treatment is completed, the next step in peptic ulcer disease therapy
is:
1. Testing for H. pylori eradication with a serum ELISA test
2. Endoscopy by a specialist
3. A proton pump inhibitor for 8 to 12 weeks until healing is complete
4. All of the above - ✔✔3. A proton pump inhibitor for 8 to 12 weeks until healing is
complete
✔✔1. Erik presents with one golden-crusted lesion at the site of an insect bite
consistent with impetigo. His parents have limited finances and request the least
expensive-treatment. Which medication would be the best choice for treatment?
1. Mupirocin (Bactroban)
2. Bacitracin and polymixin B (generic double antibiotic ointment)
3. Retapamulin (Altabax)
4. Oral cephalexin (Keflex) - ✔✔2. Bacitracin and polymixin B (generic double antibiotic
ointment)
✔✔Juakeem is a nasal methicillin resistant staphylococcus aureus (MRSA) carrier.
Treatment to eradicate nasal MRSA is mupirocin. Patient education regarding treating
nasal MRSA includes:
1. Take the oral medication exactly as prescribed.
2. Insert one-half of the dose in each nostril twice a day.
3. Alternate treating one nare in the morning and the other in the evening.
4. Nasal MRSA eradication requires at least 4 weeks of therapy, with up to 8 weeks
needed in some patients. - ✔✔2. Insert one-half of the dose in each nostril twice a day.
✔✔Instructions for applying a topical antibiotic or antiviral ointment include:
1- Apply thickly to the infected area, spreading the medication well past the borders of
the infection.
2- If the rash worsens, apply a thicker layer of medication to settle down the infection.
3- Wash hands before and after application of topical antimicrobials.
4- None of the above - ✔✔3- Wash hands before and after application of topical
antimicrobials.
SOLUTIONS RATED A+
✔✔The next step in treatment when a patient has been on proton pump inhibitors twice
daily for 12 weeks and not improving is:
1. Add a prokinetic (metoclopramide)
2. Referral for endoscopy
3. Switch to another proton pump inhibitor
4. Add a cytoprotective drug - ✔✔2. Referral for endoscopy
✔✔Infants with reflux are initially treated with:
1. Histamine2 receptor antagonist (ranitidine)
2. Proton pump inhibitor (omeprazole)
3. Anti-reflux maneuvers (elevate the head of the bed)
4. Prokinetic (metoclopramide) - ✔✔3. Anti-reflux maneuvers (elevate the head of the
bed)
✔✔Long-term use of proton pump inhibitors may lead to:
1. Hip fractures in at-risk persons
2. Vitamin B6 deficiency
3. Liver cancer
4. All of the above - ✔✔1. Hip fractures in at-risk persons
✔✔An acceptable first-line treatment for peptic ulcer disease with positive H. pylori test
is:
1. Histamine2 receptor antagonists for 4 to 8 weeks
2. Proton pump inhibitor bid for 12 weeks until healing is complete
3. Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
4. Proton pump inhibitor bid and levofloxacin for 14 days - ✔✔3. Proton pump inhibitor
bid plus clarithromycin plus amoxicillin for 14 days
✔✔Treatment failure in patients with peptic ulcer disease associated with H. pylori may
be because of:
1. Antimicrobial resistance
2. An ineffective antacid
3. Overuse of proton pump inhibitors
4. All of the above - ✔✔1. Antimicrobial resistance
✔✔If a patient with H. pylori-positive peptic ulcer disease fails first-line therapy, the
second-line treatment is:
, 1. Proton pump inhibitor bid plus metronidazole plus tetracycline plus bismuth
subsalicylate for 14 days
2. Test H. pylori for resistance to common treatment regimens
3. Proton pump inhibitor plus clarithromycin plus amoxicillin for 14 days
4. Proton pump inhibitor and levofloxacin for 14 days - ✔✔1. Proton pump inhibitor bid
plus metronidazole plus tetracycline plus bismuth subsalicylate for 14 days
✔✔After H. pylori treatment is completed, the next step in peptic ulcer disease therapy
is:
1. Testing for H. pylori eradication with a serum ELISA test
2. Endoscopy by a specialist
3. A proton pump inhibitor for 8 to 12 weeks until healing is complete
4. All of the above - ✔✔3. A proton pump inhibitor for 8 to 12 weeks until healing is
complete
✔✔1. Erik presents with one golden-crusted lesion at the site of an insect bite
consistent with impetigo. His parents have limited finances and request the least
expensive-treatment. Which medication would be the best choice for treatment?
1. Mupirocin (Bactroban)
2. Bacitracin and polymixin B (generic double antibiotic ointment)
3. Retapamulin (Altabax)
4. Oral cephalexin (Keflex) - ✔✔2. Bacitracin and polymixin B (generic double antibiotic
ointment)
✔✔Juakeem is a nasal methicillin resistant staphylococcus aureus (MRSA) carrier.
Treatment to eradicate nasal MRSA is mupirocin. Patient education regarding treating
nasal MRSA includes:
1. Take the oral medication exactly as prescribed.
2. Insert one-half of the dose in each nostril twice a day.
3. Alternate treating one nare in the morning and the other in the evening.
4. Nasal MRSA eradication requires at least 4 weeks of therapy, with up to 8 weeks
needed in some patients. - ✔✔2. Insert one-half of the dose in each nostril twice a day.
✔✔Instructions for applying a topical antibiotic or antiviral ointment include:
1- Apply thickly to the infected area, spreading the medication well past the borders of
the infection.
2- If the rash worsens, apply a thicker layer of medication to settle down the infection.
3- Wash hands before and after application of topical antimicrobials.
4- None of the above - ✔✔3- Wash hands before and after application of topical
antimicrobials.